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Does anyone have any experience with the Wiley Protocol?

Answered on August 19, 2014
Created November 01, 2012 at 12:46 AM

This is a question for any ladies with experience with bio-identical hormone therapy? Has anyone tried the Wiley Protocol? What was your experience with it? Anything postive or negative to report? How would you compare it to progesterone cream alone?

6747a5447a3440b5c87ebf5f2c1e0ead

(231)

on November 03, 2012
at 03:17 PM

Sorry, that first question mark was totally unnecessary. Oops.

6747a5447a3440b5c87ebf5f2c1e0ead

(231)

on November 03, 2012
at 02:26 PM

Thanks, Dragonfly. I have tried progesterone cream (from a compounding pharmacy) and had mixed results. My endo suggested I read Wiley's book and do some research and make my decision based on that. To clarify, I'm not menopausal. I'm 29 with PCOS/hypothyroid.

37c6c30ba2df3a1cb1b0242625bf68dd

(8)

on November 03, 2012
at 01:38 AM

So, while progesterone may be enough in early perimenopause - typically in your mid-30's - the estrogen and testosterone will soon need to be supplemented if you want to maintain appropriate cycling.

37c6c30ba2df3a1cb1b0242625bf68dd

(8)

on November 03, 2012
at 01:37 AM

Also, to answer your other question, although progesterone is the first hormone level to decrease, estrogen is lower with age as well - another common misunderstanding around the term "estrogen-dominant" is that it means there is too much estrogen, whereas it actually means that the ratio of estrogen to progesterone is off in early perimenopause. The cyclical approach is the only one we know is physiologic - the estrogen and progesterone support and counterbalance other in a cycle that creates optimal cell turnover in tissues all through the body, which is necessary for health.

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5 Answers

1
77877f762c40637911396daa19b53094

(78467)

on November 01, 2012
at 09:38 PM

Only partially relevant but "The Doper Next Door" did the male version of Wiley's protocols. What he described in interview, haven't had the chance to make it through the book yet, was a real roller-coaster that lead to screaming fights and marriage problems, also some serious fun in the sack. My impression was that her theories were just that, wild, speculative theories that weren't really based purely on hard science. Based on this interview I'd be weary of super-physiological doses, if she prescribes those for women as well as men.

1
81321c056fbbb7d29d87c4c3fa8f862d

(70)

on November 01, 2012
at 02:12 AM

This protocol was my worst nightmare. The estrogen phase was okay but the progesterone was super-super high. I gained 25 pounds, and lost a lot of hair from my scalp. Most every doctor who originally prescribed it has dropped it. Getting off the protocol is hell. Do yourself a favor and don't start.

The Wiley people put out the lie that there is only one disgruntled ex-user. But there are hundreds and more Wiley drop-outs show up on the web every day.

1
Ce41c230e8c2a4295db31aec3ef4b2ab

(32556)

on November 01, 2012
at 01:17 AM

I would avoid it, since it recommends non-physiological levels of hormones. Even the doctor who was listed as co-author of her book does not recommend this protocol..

Read this: http://wileywatch.org/

I have used Pro-gest as recommended by Dr. John Lee. His articles & books make a lot of sense to me & I have had good results from the physiological doses he recommends.

6747a5447a3440b5c87ebf5f2c1e0ead

(231)

on November 03, 2012
at 02:26 PM

Thanks, Dragonfly. I have tried progesterone cream (from a compounding pharmacy) and had mixed results. My endo suggested I read Wiley's book and do some research and make my decision based on that. To clarify, I'm not menopausal. I'm 29 with PCOS/hypothyroid.

0
37c6c30ba2df3a1cb1b0242625bf68dd

on November 03, 2012
at 01:35 AM

Works well for many people. The amounts are totally physiologic, it's a common misunderstanding that believes reproductive age levels are wrong for menopausal woman; however, her premise is that those levels signify health and protect against degenerative diseases of aging. The coauthor mentioned who became a naysayer hides behind a group of apparent disgruntled former patients were by many of their own testimonies weren't following the protocol precisely and then complained of symptoms that were indistinguishable from symptoms of menopause. If he truly has a theory that goes against the theory he originally helped to define, he should be doing studies, with controls and biopsies, etc - otherwise it is just more hype floating around in hyperspace. Give it a try, the sooner the better - all studies seem to agree that the benefit of hormone replacement is greatest the earlier you start. Good luck.

37c6c30ba2df3a1cb1b0242625bf68dd

(8)

on November 03, 2012
at 01:38 AM

So, while progesterone may be enough in early perimenopause - typically in your mid-30's - the estrogen and testosterone will soon need to be supplemented if you want to maintain appropriate cycling.

37c6c30ba2df3a1cb1b0242625bf68dd

(8)

on November 03, 2012
at 01:37 AM

Also, to answer your other question, although progesterone is the first hormone level to decrease, estrogen is lower with age as well - another common misunderstanding around the term "estrogen-dominant" is that it means there is too much estrogen, whereas it actually means that the ratio of estrogen to progesterone is off in early perimenopause. The cyclical approach is the only one we know is physiologic - the estrogen and progesterone support and counterbalance other in a cycle that creates optimal cell turnover in tissues all through the body, which is necessary for health.

0
19d1047c5576614eba6cfa442e0a7b32

(0)

on November 01, 2012
at 09:14 PM

Unlike the other two people answering, I have been on the Wiley Protocol for 3 years and like it just fine. I've held the weight I lost on it, I've stopped my bone loss, and I regained my libido. However, just alternating applying it to the underside of your arms does not work very well. You need a bigger area to spread out the Progestrone and I needed to apply the estrogen directly to the genital area to have the cycle work perfectly and not start bleeding early.
V. Anderson

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