Is heme iron a potential risk factor for colon cancer due to endogynous production of N-nitroso compounds (AKA NOCs)? Don Matesz claims so in his just-released Powered by Plants, citing "Haem, not Protein or Inorganic Iron, Is Responsible for Endogenous Intestinal N-Nitrosation Arising from Red Meat" [free text available] in which people are fed varied amounts of red meat and NOC excretion is measured (increased in high meat consumption, but low meat consumption and vegetarian cohorts had no significant difference); moreover, in "Red meat and colon cancer: Should we become vegetarians, or can we make meat safer?" (free pdf easily found), they note that "a diet high in fresh red meat (600g/d compared with 60g/d) induces a 3-fold increase in fecal nitroso-compounds" (citing another article); they note that some N-nitroso compounds are already known carcinogens although our knowledge of them is still incomplete. At least fresh meat wasn't nearly as harmful as nitrite-cured meat.
asked byCalebPetersen (0)
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on February 12, 2014
at 08:14 PM
A year and a half ago, I engaged in a debate with the vegans on Don's blog. After a while it became obvious that they advocate their position for ideological reasons (they think they are going to save the world by making everyone go vegan). But they use false, misleading or questionable health claims to try to convince others to be like them.
! wasted $400 by allowing their arguments some credibility. I am 57 and have been eating paleo for 12 years and have been eating an average of 3000mg cholesterol for about 20 months. They claimed that fasting cholesterol readings are not what counts; it is postprandial cholesterol levels that are harmful. So I had a blood test both fasted, and a few days later after eating 50g saturated fat and 4000mg cholesterol. The measurements were the same - 150mg/dl TC. A few months ago, I went on Don's site and started to seriously consider their arguments again. This time I had a bilateral carotid ultrasound which showed normal Doppler flow parameters and no sign of plaque or narrowing of the arteries. Keep in mind that cholesterol and heart disease is their chief argument and I just proved that it is false for my N=1.
So, I have learned not to give any credibility to their arguments against animal food. If you search the web, you can find plenty of debunking of the meat - colon cancer "link". I've come across that in my travels before, but I'm not going to bother any more because these vegans have thoroughly destroyed their credibility in my eyes. The best cure for the belief that eating "red meat" causes disease? Don't read vegan propaganda!
PS Speaking of heme iron, my blood iron levels were low, so I now eat blood sausage 5 days a week. That's what I think about Don's vegan arguments ;-)
on February 12, 2014
at 01:54 AM
For what it's worth, it appears that carnosine in meat may exert protective effects (eg. for this reason it protects against hydrogen peroxide generated by heme (http://thatpaleoguy.blogspot.com/2011/02/carnosine-colons-and-cancer.html).