Linus Pauling, the only man to win an unshared nobel prize twice seemed to think that heart disease was a case of chronic scurvy that could be corrected with vitamin c and lysine. Do you agree or disagree with this position, why or why not?
asked byStephen_4 (10989)
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on July 13, 2013
at 09:31 PM
In large part? I kinda doubt it. Linus Pauling was an incredible guy and his theory seems interesting, but at this point I think it would be noticeable in some of the vitamin supplementation trials that when people get vitamin C it prevents heart disease events, but as far as I'm aware this hasn't been the case.
The WACS trail for example (link), failed to find a benefits of 500 mg of the vitamin on the rates of heart attack, stroke, coronary revascularization, or cardiovascular disease deaths compared to placebo. Here's a graph of cardiovascular events between groups:
The Physicians' Health Study II trial (link) also noted no effect of 500mg vitamin C on the incidence of major cardiovascular events after 8 years of follow up.
I think it's pretty reasonable to suspect insufficient vitamin C intake (<100 mg/day I'd guess) probably contributes to atherosclerosis and the like, but I think it's merely one factor and I'm doubtful megadosing with C (recommended by Pauling) is entirely safe.