13

votes

Research references for grain unhealthiness

Answered on August 19, 2014
Created June 19, 2010 at 8:53 AM

I've gotten into some discussion about my diet with a doctor, and while he agreed on the no-sugar, no-processed food principles, he was completely taken aback at the idea of avoiding grains and the idea was new to him (he came up with usual reactions of "but grains are what allowed humanity to expand!", "they have been eaten for centuries!" and so on). He did seem to have a great deal of curiosity and open to being convinced otherwise though, and asked me for specific references on the subject.

I am doing my own search for some suitable articles (I know I've read some, but right now can't find them)... In the meantime I could do with some suggestions. Does anyone know of any solid, seminal papers (original research or review articles) that cover the essentials of grain toxicity (lectins, gluten, evolutionary maladaptation, etc.)? Bear in mind this is for a scientifically minded medically trained person, so it needs to be detailed and based on sound research. No blogs or non-peer-reviewed articles (I've got some of those and may also pass them on to him, but as extras).

Cheers!

70d9359a2086e890a4c3bccb2ba8a8cb

(2254)

on June 20, 2010
at 10:13 AM

Thanks, these are some very interesting articles which I'll actually want to have a read through myself as well, and I might pass him the one on antinutritive effects of WGA initially.

70d9359a2086e890a4c3bccb2ba8a8cb

(2254)

on June 20, 2010
at 10:08 AM

I have searched Pubmed, yes, and found some good articles, but annoyingly there are some specific ones I know I've read but can't remember the author and so had some trouble finding them just with keywords. But I think I have enough now for a "first approach". @Patrik, sure I'll report back here to let you all know how it goes!

70d9359a2086e890a4c3bccb2ba8a8cb

(2254)

on June 20, 2010
at 10:05 AM

Many thanks pieter! That's the article I was thinking of, as I remembered having read it last year but I couldn't remember the author (as I didn't really know who Cordain was at the time, so it hadn't registered in my mind). It covers everything in detail with plenty of references. Let's just hope the doc's going to have the patience to read through it (or at least some of it)!

93f44e8673d3ea2294cce085ebc96e13

(10502)

on June 19, 2010
at 08:04 PM

@archaea -- please let us know how successful you were in this endeavor.

667f6c030b0245d71d8ef50c72b097dc

(15976)

on June 19, 2010
at 12:25 PM

that is exactly what i was going to post! While i refrain from using Cordain's website as a go-to reference when first telling people about our way of eating, only because his site has a very commercial "buy this, buy that" kindof feel, it is indeed a wealth of hardcore scientific, peer reviewed stuff.

5de2fffda92c0bf2be7ede10cad55546

(1781)

on June 19, 2010
at 12:05 PM

Have you tried searching Pubmed?

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5 Answers

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10
89e238284ccb95b439edcff9e123671e

(10299)

on June 19, 2010
at 10:25 AM

This paper by Loren Cordain is probably one of the best:

http://www.direct-ms.org/pdf/EvolutionPaleolithic/Cereal%20Sword.pdf

Good luck convincing your doctor!

70d9359a2086e890a4c3bccb2ba8a8cb

(2254)

on June 20, 2010
at 10:05 AM

Many thanks pieter! That's the article I was thinking of, as I remembered having read it last year but I couldn't remember the author (as I didn't really know who Cordain was at the time, so it hadn't registered in my mind). It covers everything in detail with plenty of references. Let's just hope the doc's going to have the patience to read through it (or at least some of it)!

667f6c030b0245d71d8ef50c72b097dc

(15976)

on June 19, 2010
at 12:25 PM

that is exactly what i was going to post! While i refrain from using Cordain's website as a go-to reference when first telling people about our way of eating, only because his site has a very commercial "buy this, buy that" kindof feel, it is indeed a wealth of hardcore scientific, peer reviewed stuff.

5
5de2fffda92c0bf2be7ede10cad55546

(1781)

on June 19, 2010
at 12:43 PM

Try: Antinutritive effects of wheat-germ agglutinin and other N-acetylglucosamine-specific lectins.

http://tiny.cc/71m8z

http://tiny.cc/2vwqc

http://tiny.cc/l1on3

http://tiny.cc/e44m4

http://tiny.cc/eo9ha

http://tiny.cc/efn65

http://tiny.cc/77gqc

They were all huge URL's so I shortened them up for you. Hope this helps, good luck.

70d9359a2086e890a4c3bccb2ba8a8cb

(2254)

on June 20, 2010
at 10:13 AM

Thanks, these are some very interesting articles which I'll actually want to have a read through myself as well, and I might pass him the one on antinutritive effects of WGA initially.

2
F6c1df7d5699661bd1f0d6d0a6c17fc6

on September 09, 2010
at 04:00 PM

Here's epidemiological data and analysis of that data that shows a huge correlation between wheat intake and heart disease. http://rawfoodsos.com/2010/09/02/the-china-study-wheat-and-heart-disease-oh-my/

1
5cc9908801b79ff820bbc1eb7ac01b8f

on September 25, 2010
at 03:46 PM

This is a minor aside, but I noticed there actually isn't a Wikipedia article for wheat germ agglutinin. I don't have the specific expertise on WGA, but I do have a pretty strong bio background as a former grad student. Is anyone interested in collaborating on starting up a Wikipedia article? We could do so on Google Docs.

1
Be1dbd31e4a3fccd4394494aa5db256d

(17969)

on September 09, 2010
at 04:06 AM

More Cordain. http://thepaleodiet.blogspot.com/2010/07/type-2-diabetes-and-endotoxemia.html

If you want to pwn a grain, look to Cordain. And that rhymes :)

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