5

votes

Scientific Evidence Gluten messes up healthy people?

Answered on September 12, 2014
Created July 10, 2011 at 12:51 PM

Do we have this? According to Chris Masterjohn, we don't.

Chris Masterjohn on How to Properly Interpret Ex Vivo Studies -- Gluten and Leaky Gut As an Example:

Consequently, neither Dr. Fasano's most recent study showing that non-celiac gluten-sensitive patients do not have leaky gut nor the double-blind controlled trial showing that gluten does not cause leaky gut in non-celiac gluten-sensitive patients rule out the possibility that there is some subset of non-celiac subjects, somewhere on the face of the earth, perhaps autistics, perhaps not, who actually do respond to gluten by developing leaky guts. But to my knowledge there is no solid evidence of this and if anyone knows of some, again, please post it in the comments.

But according to Aaron B.(resident paleo hacker)

If you think science hasn't already provided "undeniable evidence wheat messes you up," then I'd say you're setting the bar for "undeniable" so high it can never be reached.

Can someone show me this science Aaron B eludes to?

64433a05384cd9717c1aa6bf7e98b661

(15236)

on March 25, 2012
at 10:20 PM

Okay Coja, there is evidence that EVERYONE has an immune reaction to gluten. I don't have the paper on this computer but it exists nonetheless. Also, this website is about thinking and stimulating people's thoughts.

E05b8d2c9ae8a9a92341785f342f131d

(346)

on March 25, 2012
at 06:59 PM

The prevalence of these paleo-skeptic questions and responses i. The paleo community is what I love about it most

E05b8d2c9ae8a9a92341785f342f131d

(346)

on March 25, 2012
at 06:57 PM

Also, the question asked for evidence. You ignored this and gave a question as an answer. Sorry to be rude, but you did ask why you got downvotes.

E05b8d2c9ae8a9a92341785f342f131d

(346)

on March 25, 2012
at 06:54 PM

I think you got downvotes because conspiracy theories are a typical last resort in the face of a complete lack of evidence.

219ce991d8c94447870c824680de53e0

(457)

on August 04, 2011
at 03:28 PM

I have to say, and I am sure this will be unpopular but, I have never had an adverse reaction to gluten. I simply stopped eating because of the Paleo tenets. I have enjoyed tremendous weight loss sense goign Paleo but could easily eat a sandwich with little to know issue whatsoever. Does this mean i will? No but it seems like a lot of people gravitate towards the Paelo lifestyle because they cant and then realize the other benefits as ancillary upsides to a health condition. Just my 2 cents.

C1fb8666b1ae085507a76a4c494e4f0a

on July 11, 2011
at 09:52 PM

Going back to gluten and having no problems happens... but that doesn't mean they won't have problems in future. (they may, they may not). It isn't always an instant reaction.

226b10cbb6b1d3530b00d2d84a2dc86e

(3313)

on July 11, 2011
at 03:58 PM

VERY interesting information. Thank you for that.

F52b51135f2c47eb46c986fdc9760b9b

(180)

on July 11, 2011
at 11:00 AM

Yes, it's possible that research proving gluten is harmful is being suppressed, but you could say that about anything you want to believe but which you don't have any real proof of.

64433a05384cd9717c1aa6bf7e98b661

(15236)

on July 11, 2011
at 04:53 AM

lol thanks wozza

2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 11, 2011
at 02:21 AM

That's not mentioning the animal studies, the interaction with opioid receptors, the over 90 other compounds found in wheat which are not studied and we don't have a test for(those that are all show desructive effects). Or that Dr. Kenneth Fine's broader scope testing showed that 1 in 3 people react to wheat. It's garbage that should be genocided of the planet, instead of being the number one staple crop.

2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 11, 2011
at 02:20 AM

That's not mentioning the animal studies, the interaction with opioid receptors, the over 90 other proteins found in wheat which are not studied and we don't have a test for(those that are all show desructive effects). Or that Dr. Kenneth Fine's broader scope testing showed that 1 in 3 people react to wheat. It's garbage that should be genocided of the planet, instead of being the number one staple crop.

2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 11, 2011
at 02:20 AM

Gliadin upregulates zonulin, increasing intestinal permeability: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16635908&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum The above is basically Alicio Fasano's proposed mechanism shown to work.

2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 11, 2011
at 02:19 AM

WGA perturbed the integrity of the epithelium and increased the permeability of the tissue in a dose- and time-dependent manner: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16102568&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum Along with a few wheat storage proteins WGA also happens to be an insulin memetic, interacting directly with the receptor sites.

2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 11, 2011
at 02:18 AM

Yes, it's toxic at nanomolar concentrations. So it doesn't need to be heat stable, because any nanomole that survives will damage the brush border. Add the other effects of wheat(some below) and multiply by a few months of consuming this staple food and additive.

C2502365891cbcc8af2d1cf1d7b0e9fc

(2437)

on July 11, 2011
at 02:01 AM

Here's a vote. Now stop whingeing.

11dff0119e8ca2babb4acf40a5ef6ac4

(233)

on July 11, 2011
at 01:59 AM

Well, that's kind of the point, isn't it? Unless what you're really trying to say is that to prove that wheat is a problem in general the standard would have to be that every person in the world would have to have a provable negative response. Let me put it this way. At what point do you draw the line? If you took a random sampling of 100 healthy people & ran them through an elimination/challenge test for gluten, how many of those 100 people would have to have a negative reaction to gluten for you to conclude that gluten causes problems for otherwise healthy people?

34a367e60db77270bd7096dc04270fdc

(4171)

on July 10, 2011
at 11:27 PM

I gave you a +1!

34a367e60db77270bd7096dc04270fdc

(4171)

on July 10, 2011
at 11:23 PM

I also did not state that my autoimmune disease was caused by my eating grains, all I said is that it is possible. As far as other family members, no they do not have an autoimmune disease. My brother has stopped eating grains due to being pre-diabetic. The particular autoimmune disease I have mostly affects women.

34a367e60db77270bd7096dc04270fdc

(4171)

on July 10, 2011
at 11:17 PM

No I have not been paleo for a few years. I first cut out grains a couple of years ago. I have not been consistently grain free since that time. I'll eat clean for a few weeks then I'll end up eating pizza or a sandwich etc. Also yes I have been checked out, never had any issues when I was younger, but I can tell you that it was around October of last year that I started developing symptoms of an autoimmune disease. It's only been in the last couple of months working with a rheumatologist and having a ton of blood tests that I've found out it was an autoimmune disease.

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:45 PM

I found this http://www.ncbi.nlm.nih.gov/pubmed/19332085 "At nanomolar concentrations WGA stimulates the synthesis of pro-inflammatory cytokines and thus the biological activity of WGA should be reconsidered by taking into account the effects of WGA on the immune system at the gastrointestinal interface. These results shed new light onto the molecular mechanisms underlying the onset of gastrointestinal disorders observed in vivo upon dietary intake of wheat-based foods."

64433a05384cd9717c1aa6bf7e98b661

(15236)

on July 10, 2011
at 10:44 PM

it may but it's also a legitimate question

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:37 PM

sounds like a conspiracy theory

64433a05384cd9717c1aa6bf7e98b661

(15236)

on July 10, 2011
at 10:36 PM

why would I get 2 downvotes for this?

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:36 PM

So you've been paleo for a few years? and just recently found out your autoimmune, were you checked out in the past?

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:34 PM

I really doubt your autoimmune disease is from wheat or gluten. Your other family members eat wheat/gluten right?

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:33 PM

We also have lots of N=1 of people giving up gluten sometimes for years and going back to gluten with no problems. People like Matt Stone, Daniel Vitalis, Chris Masterjohn.

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:30 PM

Can you show me your studies. I looked and couldn't find anything solid against WGA.

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:30 PM

I looked it up and found lots of contradictions in your statement. Check this out for example http://digitool.library.colostate.edu/webclient/DeliveryManager?pid=75153 "According to the protocol utilized, WGA was not detected in venous plasma samples from any of the subjects following consumption of 50 g of wheat germ, thereby indicating that the available WGA in wheat germ either did not breach the gut barrier"..."Processing appeared to alleviate the bioactivity of WGA in one study that showed that the lectin was no longer detectable in wholemeal pastas after cooking at 65º C for 30 minutes"

667f6c030b0245d71d8ef50c72b097dc

(15976)

on July 10, 2011
at 09:35 PM

I'd agree Olivia. Which is why rather than citing a study or something I find it easier and more convenient to simply answer the why with a, "because I just feel very good eating this way." is there a better answer?

667f6c030b0245d71d8ef50c72b097dc

(15976)

on July 10, 2011
at 09:33 PM

Another good point. This goes back to the "don't believe me? Just try it" line of discussion. I got one friend completely into the paleo thing from exactly this. She's doing very well.

667f6c030b0245d71d8ef50c72b097dc

(15976)

on July 10, 2011
at 09:32 PM

Good point. A lot of nutritional information we believe and wish more people knew about fall into a similar dilemma: that the implications of a government body coming out and acknowledging a harm in something they've professed to be healthy are simply too great. So, the truth of the nutrition doesn't matter. Rather, a more political issue of towing the line and culpability.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on July 10, 2011
at 08:52 PM

There is none.....not one.

7d0c3ea9bf8be00b93e6433d8f125ac3

(7540)

on July 10, 2011
at 08:37 PM

Great answer, I agree too. And I think that, in the meantime, the paleo community should be careful to avoid falling into zealous attachment to a nutritional tenet without rock-solid evidence for all our claims. Isn't that what we always criticise conventional dietary advice for? I mean, look at how upset a few (not most, mind you) people in the paleo community get if you try to suggest that maybe eating some pasta once a week isn't basically the same thing as drinking arsenic once a week, or that gluten isn't a death sentence for everyone.

98bf2ca7f8778c79cd3f6c962011cfdc

(24286)

on July 10, 2011
at 03:48 PM

I agree completely. I wouldn't say there is "no solid evidence" but not enough evidence to meet scientific standards. I also believe that the evidence will be coming as more studies are done.

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 02:10 PM

I am not convinced gluten has a health benefit. My question is, does gluten mess up healthy people?

E5c7f14800c5992831f5c70fa746dc5c

(12857)

on July 10, 2011
at 02:09 PM

I am not convinced gluten has a health benefit. My question does gluten mess up healthy people?

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9 Answers

7
2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 10, 2011
at 08:39 PM

Yes, it has been proven. Look up WGA on Pubmed. It trashes the brush border of intestinal lining whether you digest gluten or not. Are there people who are somehow not affected by it? Maybe. But they have not been found yet.

We have a mechanism for direct damage and a ton of massive negative associations, but we DO NOT have a mechanism for avoiding damage or positive associations. So the logically sound thing to do is to consider wheat a toxic food and avoid it.

2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 11, 2011
at 02:20 AM

Gliadin upregulates zonulin, increasing intestinal permeability: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16635908&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum The above is basically Alicio Fasano's proposed mechanism shown to work.

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:30 PM

I looked it up and found lots of contradictions in your statement. Check this out for example http://digitool.library.colostate.edu/webclient/DeliveryManager?pid=75153 "According to the protocol utilized, WGA was not detected in venous plasma samples from any of the subjects following consumption of 50 g of wheat germ, thereby indicating that the available WGA in wheat germ either did not breach the gut barrier"..."Processing appeared to alleviate the bioactivity of WGA in one study that showed that the lectin was no longer detectable in wholemeal pastas after cooking at 65º C for 30 minutes"

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:45 PM

I found this http://www.ncbi.nlm.nih.gov/pubmed/19332085 "At nanomolar concentrations WGA stimulates the synthesis of pro-inflammatory cytokines and thus the biological activity of WGA should be reconsidered by taking into account the effects of WGA on the immune system at the gastrointestinal interface. These results shed new light onto the molecular mechanisms underlying the onset of gastrointestinal disorders observed in vivo upon dietary intake of wheat-based foods."

2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 11, 2011
at 02:19 AM

WGA perturbed the integrity of the epithelium and increased the permeability of the tissue in a dose- and time-dependent manner: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16102568&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum Along with a few wheat storage proteins WGA also happens to be an insulin memetic, interacting directly with the receptor sites.

2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 11, 2011
at 02:21 AM

That's not mentioning the animal studies, the interaction with opioid receptors, the over 90 other compounds found in wheat which are not studied and we don't have a test for(those that are all show desructive effects). Or that Dr. Kenneth Fine's broader scope testing showed that 1 in 3 people react to wheat. It's garbage that should be genocided of the planet, instead of being the number one staple crop.

2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 11, 2011
at 02:20 AM

That's not mentioning the animal studies, the interaction with opioid receptors, the over 90 other proteins found in wheat which are not studied and we don't have a test for(those that are all show desructive effects). Or that Dr. Kenneth Fine's broader scope testing showed that 1 in 3 people react to wheat. It's garbage that should be genocided of the planet, instead of being the number one staple crop.

226b10cbb6b1d3530b00d2d84a2dc86e

(3313)

on July 11, 2011
at 03:58 PM

VERY interesting information. Thank you for that.

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:30 PM

Can you show me your studies. I looked and couldn't find anything solid against WGA.

2d5221fa80d04a3d8ac6f471f9feae81

(894)

on July 11, 2011
at 02:18 AM

Yes, it's toxic at nanomolar concentrations. So it doesn't need to be heat stable, because any nanomole that survives will damage the brush border. Add the other effects of wheat(some below) and multiply by a few months of consuming this staple food and additive.

219ce991d8c94447870c824680de53e0

(457)

on August 04, 2011
at 03:28 PM

I have to say, and I am sure this will be unpopular but, I have never had an adverse reaction to gluten. I simply stopped eating because of the Paleo tenets. I have enjoyed tremendous weight loss sense goign Paleo but could easily eat a sandwich with little to know issue whatsoever. Does this mean i will? No but it seems like a lot of people gravitate towards the Paelo lifestyle because they cant and then realize the other benefits as ancillary upsides to a health condition. Just my 2 cents.

6
1d9af5db8833413037be3ac48964714f

on July 10, 2011
at 02:29 PM

From what I have read, the evidence just isn't there. I suspect that evidence will be coming as more studies are done, but I can't prove it.

I have clear evidence that eating gluten grains causes me to get skin rashes. I believe that eliminating gluten has also contributed to a number of other health benefits I experience on paleo. But we must clearly distinguish between what has been established empirically and what is merely suggested by multiple lines of evidence and reasoning.

98bf2ca7f8778c79cd3f6c962011cfdc

(24286)

on July 10, 2011
at 03:48 PM

I agree completely. I wouldn't say there is "no solid evidence" but not enough evidence to meet scientific standards. I also believe that the evidence will be coming as more studies are done.

667f6c030b0245d71d8ef50c72b097dc

(15976)

on July 10, 2011
at 09:35 PM

I'd agree Olivia. Which is why rather than citing a study or something I find it easier and more convenient to simply answer the why with a, "because I just feel very good eating this way." is there a better answer?

7d0c3ea9bf8be00b93e6433d8f125ac3

(7540)

on July 10, 2011
at 08:37 PM

Great answer, I agree too. And I think that, in the meantime, the paleo community should be careful to avoid falling into zealous attachment to a nutritional tenet without rock-solid evidence for all our claims. Isn't that what we always criticise conventional dietary advice for? I mean, look at how upset a few (not most, mind you) people in the paleo community get if you try to suggest that maybe eating some pasta once a week isn't basically the same thing as drinking arsenic once a week, or that gluten isn't a death sentence for everyone.

E05b8d2c9ae8a9a92341785f342f131d

(346)

on March 25, 2012
at 06:59 PM

The prevalence of these paleo-skeptic questions and responses i. The paleo community is what I love about it most

4
64433a05384cd9717c1aa6bf7e98b661

(15236)

on July 10, 2011
at 07:45 PM

Is it possible that the implications of implicating gluten as being harmful to EVERYONE are too much for the scientific community and the government to be responsible for?

I mean, what would be the public response to a government statement that said gluten causes inflammation, which can lead to auto-immune diseases, heart disease, etc.

Even if there were indisputable evidence I don't see it being released.

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:37 PM

sounds like a conspiracy theory

64433a05384cd9717c1aa6bf7e98b661

(15236)

on July 10, 2011
at 10:44 PM

it may but it's also a legitimate question

64433a05384cd9717c1aa6bf7e98b661

(15236)

on July 10, 2011
at 10:36 PM

why would I get 2 downvotes for this?

667f6c030b0245d71d8ef50c72b097dc

(15976)

on July 10, 2011
at 09:32 PM

Good point. A lot of nutritional information we believe and wish more people knew about fall into a similar dilemma: that the implications of a government body coming out and acknowledging a harm in something they've professed to be healthy are simply too great. So, the truth of the nutrition doesn't matter. Rather, a more political issue of towing the line and culpability.

C2502365891cbcc8af2d1cf1d7b0e9fc

(2437)

on July 11, 2011
at 02:01 AM

Here's a vote. Now stop whingeing.

34a367e60db77270bd7096dc04270fdc

(4171)

on July 10, 2011
at 11:27 PM

I gave you a +1!

64433a05384cd9717c1aa6bf7e98b661

(15236)

on July 11, 2011
at 04:53 AM

lol thanks wozza

F52b51135f2c47eb46c986fdc9760b9b

(180)

on July 11, 2011
at 11:00 AM

Yes, it's possible that research proving gluten is harmful is being suppressed, but you could say that about anything you want to believe but which you don't have any real proof of.

E05b8d2c9ae8a9a92341785f342f131d

(346)

on March 25, 2012
at 06:57 PM

Also, the question asked for evidence. You ignored this and gave a question as an answer. Sorry to be rude, but you did ask why you got downvotes.

E05b8d2c9ae8a9a92341785f342f131d

(346)

on March 25, 2012
at 06:54 PM

I think you got downvotes because conspiracy theories are a typical last resort in the face of a complete lack of evidence.

64433a05384cd9717c1aa6bf7e98b661

(15236)

on March 25, 2012
at 10:20 PM

Okay Coja, there is evidence that EVERYONE has an immune reaction to gluten. I don't have the paper on this computer but it exists nonetheless. Also, this website is about thinking and stimulating people's thoughts.

3
510bdda8988ed0d4b0ec0b738b4edb73

(20888)

on July 11, 2011
at 03:40 PM

The question you're asking can't be answered. Basically when it comes to applying science to our diets there are two approaches (I think we need to use both because there are limits in either case).

First, there's the "Gary Taubes" approach. Where he cares mostly about observables. This is close to your question: I.e., "does gluten mess up healthy people"? In this situation you need to both define "mess up" and "healthy people", and then do a study and look at the outcomes at the level of "what happened to the people".

The other approach (and where I lean), I'll call the "Mat Lalonde" approach. (I probably lean this way because I'm a chemist too.) In this approach we concern ourselves with the biochemical mechanisms: Glutens cause some types of cells to "fall apart". The types of cells that it interferes with are in the gut. When the gut lining breaks down, whole proteins get into the blood. When whole proteins get into the blood you can get autoimmune responses. Etc. Here we're talking at the chemical level. And as you're concerned maybe that doesn't happen with "healthy" people and there may not be an observable.

So back to your question, you want "scientific evidence" that gluten "messes up" "healthy people". I put the quotes in there because those terms need to be defined. Lets start from the back of the question:

"Healthy People" How do you define healthy people? There are lots of people that may appear healthy but have some weird skin rash that they wouldn't attribute to gluten, they may just call it dry skin. Or someone may have a permanently runny nose, and they just say it's allergies. So you'll need some (hopefully simple and easy to defend to your audience) metric that distinguishes between health and non-healthy people

"Messes Up" What do you mean messes up? Autoimmune problems? Seemingly random diarrhea? Chronically runny nose? Skin rashes? Bloating after eating? You need to pick the metric you're comparing in your study.

"Scientific Evidence" Given that you've defined healthy people (at a level that your audience can understand) and that you've defined "messes up" to single out 1 or 2 (at most) illnesses. You need to split your people up into multiple groups, control their food, and hopefully not have any other confounds in your study.

I'm stopping here before this gets longer, but in reality science is hard, and it's even harder to get right. That's why you'll never find a "definitive" study either way that something is good or bad for you, you have to look at how the good and bad were defined in THAT study. That's why I generally lean towards the mechanistic approach, we can understand what the molecules are doing and then extrapolate and say "if I don't eat gluten, I won't damage my gut and get all the problem that come along with a damaged gut". Then, as I did, I quit eating gluten and things are better. So, FOR ME, I'm happy.

One study (Key's Seven Country Study) is the only study out there that said "fat is bad" and then people interpreted it as the definitive study that and said that fat was bad. There was no mechanistic given. Just "fat messes up people" and everyone bought it.

0
85ff2ce79d8b21d2e67e4e5530b696cf

on August 03, 2011
at 11:28 PM

None.

Zero.

Period.

0
11dff0119e8ca2babb4acf40a5ef6ac4

(233)

on July 10, 2011
at 03:34 PM

How would you go about proving this? You'd need a group of healthy people who've never (or not recently) eaten gluten for a baseline before giving half of them gluten and testing both for differences.

Or you could do what most of us have done and take people (us) who have been eating gluten all their lives, remove the gluten from their diets, and then find out if they're healthier than they were eating gluten. Everyone here who feels better when they're not eating gluten raise your hand. Not exactly scientific, but if you're waiting around for the scientific community to do that study, don't hold your breath.

11dff0119e8ca2babb4acf40a5ef6ac4

(233)

on July 11, 2011
at 01:59 AM

Well, that's kind of the point, isn't it? Unless what you're really trying to say is that to prove that wheat is a problem in general the standard would have to be that every person in the world would have to have a provable negative response. Let me put it this way. At what point do you draw the line? If you took a random sampling of 100 healthy people & ran them through an elimination/challenge test for gluten, how many of those 100 people would have to have a negative reaction to gluten for you to conclude that gluten causes problems for otherwise healthy people?

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:33 PM

We also have lots of N=1 of people giving up gluten sometimes for years and going back to gluten with no problems. People like Matt Stone, Daniel Vitalis, Chris Masterjohn.

667f6c030b0245d71d8ef50c72b097dc

(15976)

on July 10, 2011
at 09:33 PM

Another good point. This goes back to the "don't believe me? Just try it" line of discussion. I got one friend completely into the paleo thing from exactly this. She's doing very well.

C1fb8666b1ae085507a76a4c494e4f0a

on July 11, 2011
at 09:52 PM

Going back to gluten and having no problems happens... but that doesn't mean they won't have problems in future. (they may, they may not). It isn't always an instant reaction.

0
34a367e60db77270bd7096dc04270fdc

(4171)

on July 10, 2011
at 02:53 PM

I never thought I had any problems with gluten and I absolutely love bread so I've eaten I'm sure, more than my fair share over the years. That being said, a couple of years ago when I first read about paleo, I cut all grains and bread out for about 2-3 months before the occasional sandwich started to creep back into my diet. It was at that point when I started paying attention to how I felt whenever I would eat bread/gluten. I felt bloated, sluggish, and just overall shitty. Since then, knowing that gluten does have an effect on me, it has still been a struggle to not slip back into eating it periodically.

And now, I turned 40 last week and my present was finding out I have developed an autoimmune disease. I cannot say that grains or gluten are to blame but it certainly is possible and no one else in my family has ever had an autoimmune disease so I can't trace it in genes either.

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:34 PM

I really doubt your autoimmune disease is from wheat or gluten. Your other family members eat wheat/gluten right?

34a367e60db77270bd7096dc04270fdc

(4171)

on July 10, 2011
at 11:17 PM

No I have not been paleo for a few years. I first cut out grains a couple of years ago. I have not been consistently grain free since that time. I'll eat clean for a few weeks then I'll end up eating pizza or a sandwich etc. Also yes I have been checked out, never had any issues when I was younger, but I can tell you that it was around October of last year that I started developing symptoms of an autoimmune disease. It's only been in the last couple of months working with a rheumatologist and having a ton of blood tests that I've found out it was an autoimmune disease.

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 10:36 PM

So you've been paleo for a few years? and just recently found out your autoimmune, were you checked out in the past?

34a367e60db77270bd7096dc04270fdc

(4171)

on July 10, 2011
at 11:23 PM

I also did not state that my autoimmune disease was caused by my eating grains, all I said is that it is possible. As far as other family members, no they do not have an autoimmune disease. My brother has stopped eating grains due to being pre-diabetic. The particular autoimmune disease I have mostly affects women.

-1
226b10cbb6b1d3530b00d2d84a2dc86e

(3313)

on July 10, 2011
at 02:01 PM

Drink gluten smoothies for breakfast every morning if you're convinced it provides some health benefit.

E5c7f14800c5992831f5c70fa746dc5c

(12857)

on July 10, 2011
at 02:09 PM

I am not convinced gluten has a health benefit. My question does gluten mess up healthy people?

36b7a2776d028dc8d5743e2e56ece34d

(812)

on July 10, 2011
at 02:10 PM

I am not convinced gluten has a health benefit. My question is, does gluten mess up healthy people?

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