Mitigating deleterious effects of massive gluten exposure?

Answered on August 19, 2014
Created October 04, 2010 at 4:50 AM

I just had a large dose of wheat flour and sugar in the form of bread pudding, about an hour ago, after having been largely wheat-free for years (except for the odd bit of soy sauce, or something minor like that). I'm already feeling the potential symptoms of gluten overexposure - spacey, dazed, almost narcotic feeling; slight headache; stomach pains; sleepiness; and overheating - but I'm wondering if anyone has a good tip for feeling better.

Fast the next day?

Get a big dose of exercise?

Megadose a supplement/vitamin?

Sleep it off?

Or just learn from my mistake?

I'm sure you've been in my shoes before. How did you mitigate the damage and start to feel better, sooner?



on October 04, 2010
at 09:39 PM

Physical effects subsided rather quickly (several hours), but later last night I was hit with a flood of depressive thought patterns as I tried to sleep. I was stuck in a negative thought loop - half awake, kinda dreamy, a bit raving. Very strange. What helped was getting up and going for a walk with the dog under the bright moonlight at 3 AM, just to occupy my brain. I feel pretty good today. Did a short, intense workout (pullups and glute ham raises) and went for another walk. Ate some yogurt and a sweet potato. Just a bit of bloating. Lesson learned; thanks for the advice, folks!



on October 04, 2010
at 01:03 PM

Isn't it a bad idea to take aspirin on an empty stomach?



on October 04, 2010
at 04:54 AM

This wins my award for the best title!! :D

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7 Answers

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on October 04, 2010
at 12:20 PM

There are "Gluten Enzymes" that help break down gluten... But they're really only useful at time of consumption

Knowing what you do about how You react, I'd avoid another mistake and take this as a valuable lesson

That being said, Heres what to avoid and a few that might help...


  • Alcohol

  • Caffeine

  • NSAIDs

  • Spicy Food.

Things to try

  • L-Glutamine: Glutamine is required for the production of both intestinal mucus and Secretary Immunoglobulin Type A (SIgA).

  • Fiber: Generally dont recommend, in this case, a lesser evil to sweep the greater evil out.

  • Glucosamine: essential for the secretion of the mucus that creates a protective lining on top of the cells of the gut.

  • Milk Thistle - shown to have antiinflammatory effect in the gut, increases levels of glutathione.

  • Aloe contains mucilaginous polysaccharides, an anti-inflammatory for the gut.



on October 04, 2010
at 07:09 PM

I find fasting makes me feel best after getting glutened, if anything to avoid adding more food that will want to leave expeditiously.

Get some digestive enzymes in there, some probiotics to replenish and some warm ginger tea or something.

Robb Wolf told me that heavy exercise will further irritate the gut lining so its not such a god idea to do anything too strenuous after getting sick. At least it wont particularly help. Also you may find your performance inhibited with your muscles not firing as well as they could.

Gluten = DEATH!


on October 04, 2010
at 10:57 AM

I guess the "lesson" part is your best option ;-) And the damage depends also on your individual sensitivity to gluten, if your gut was completely healthy and so on. Your reaction should depend on how you feel, try to listen to your body - do you feel like eating? drinking? fasting? sleeping? I think getting back on the wagon is the best option, with no treats or light "cheats" for a while.



on October 04, 2010
at 05:37 AM

What can you do to mitigate the metabolic effects/damage? Probably not much. You should probably drink extra water as carbs need more water to process. The wheat will do what damage it will do to the gut. The sugar will boost your insulin/blood sugar for a bit. You may be able to lesson that with some exercise, but in the long run, it probably won't matter much.

THe other kind of mitigation is just for symptoms. If you feel bad, try rest and relaxation. (plus water as already mentioned) If digestion is unbalanced, don't eat again until you are hungry and then eat only bland food. From your symptoms, sounds like the pudding wasn't worth it! ;-P



on November 28, 2010
at 08:22 PM

I just ate lunch at a Buddhist temple, and even though they seemed to understand that some people can't eat wheat, all the food was full of fake meats of different sorts. They assured me that the dish I chose was gluten-free, but they used the same utensils to serve everything, and I grabbed a soup that I thought was just vegetable broth, but it turned out to have various fake meats at the bottom. About an hour later, I felt nauseous and dizzy, and my stomach was killing me. Then explosive diarrhea. I'm starting to feel a little better now, and sipping on some turkey stock I made over T-day with some ginger and butter in it. It's helping. I think I'm going to take it easy and have a steak in a few hours.



on October 04, 2010
at 12:56 PM

I did that this weekend - I was traveling on Saturday, ate some pizza for lunch and salad. I didn't eat a ton or anything, just 2 small slices and a cinnamon roll (CiCi's Pizza). Then didn't eat again until about 8pm but it was General Tso's chicken, steamed rice, & egg roll. I haven't eaten anything like that for quite a while. I felt sick after, most of the symptoms described above. So I fasted all day Sunday, I felt all out of sorts most of the day with nausea, bloating, and lethargy. I guess we have to just ride it out when we do that to ourselves.



on October 04, 2010
at 05:27 AM

Personally I like fasting with lots of water, maybe a asprin, followed by a clean salad or something which in my mind, I imagine helping to move out any left overs of the badness. This is my personal method, and I have no scientific basis for this method. Its a good question so I am curious of anyone does have good formula.



on October 04, 2010
at 01:03 PM

Isn't it a bad idea to take aspirin on an empty stomach?

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