We are our genes, but our genes are not our fate. As a paleo community we tend to concern ourselves greatly with our natural heritage, our predispositions and our gene expressions. We are very interested in bringing out the best of what we are and... (more)
Anyone tried it? What is better NAC or gluthaionine? I found this interesting paper which supports supplementation with NAC and couple of other gluthaionine precursors: http://www.ncbi.nlm.nih.gov/pubmed/17914184 Any APOE 4/4 who actually tried... (more)
Since there is talk about gaining weight all over paleo hacks, i was wondering when played defensive end in high school when i weighed 240 (im 190 now) i was benching 325 for reps, powercleaning 260 for reps, and deadlifting 450-480 pounds, this... (more)
I'm being hopeful... This is a long shot and I'm pretty sure nobody will answer...but is there anyone with NF out there who is on paleo? Do you think that it will help with any of the symptoms? Thanks in advance.
I'll start with my question: Do you agree with Melissa McEwen's critique of Jack Kruse's (mis)use of evolutionary biology? I should note that I am a fan of both McEwen and Kruse. McEwen's blog post is... (more)
You have no idea how hard that post was to write. I mean, it's so hard to read Dr. Kruse's writing and find consistant threads in it. He has references on the bottom of some post, but mostly they do not correspond to things in his posts that I... (more)
I know that strict paleo doesn't include grains, dairy or legumes. However, I think the majority of people here are flexible with what they eat. Butter and cream seem to be sacred gods on this site. I was wondering if I could do some sort of poll... (more)
Hi! Because of constipation, which is now better, my G.I specialist got me to take a blood test to see if I have celiac or not. The results were that I'm a carrier for Celiac disease but it came back negative. My aunt didnt develop properly... (more)
How much do you consider your family history (or gene testing, if you've done it) when making lifestyle decisions? For example, if you find out tomorrow that many of your older relatives had/have a particular cancer, would you begin to make... (more)
I have a question that has been on my mind for a while now, and I am wondering what some other people think of this. So, having been strict Paleo for over a year now, that is my choice, I know that. my Significant other, is a wonderfully... (more)
It may not be a helpful answer, but I'd really recommend trying to look beyond weight as the only measure of health. I'd also be cautious of drawing conclusions about what other people are eating or doing when you don't see them. I'm sure there... (more)
You probably are not looking for grounds upon which to sue 23andme, but... The word "actionable" means "affording grounds for legal action" and "violating principles of justice." I get that you mean something closer to: "Based on one's genome,... (more)
Hi! Who here legitimately forgets to eat? Or has less interest in food than people in general? I've had a brief history of overeating, but that was due to addictive foods on the S.A.D that I leeched onto after being through a long period of... (more)
Loaded question I know, but this is a really interesting piece on DNA being changed by the foods we eat. We Incorporate Genetic Information From the Food We Eat, New Study Finds
A friends status on FB got me thinking about this. Her son was using a toy as a gun. She has no idea how he knows about guns. A few comments suggested that boys just do this kind of thing - it's genetic. My DS is always surprising me and using... (more)
Just got my 23andme data back -- would love to know what is the best way to get the most actionable data out of it. What should I look at that will let me make a change in my diet, lifestyle, fitness today? Anything? (more)
I've always wondered if the different levels in carb tolerance that we often see has anything to do with genetic differences that related to ethnicity. I, for example, am half Italian (mother born there) and half Jewish-Russian (perhaps Belarus;... (more)
Chris and I were having a conversation about how some people do really awesome on pretty low carb and some people feel sick. I started getting curious about whether this might have something to do with "neanderthal ancestry." If you have DNA data... (more)
I had always assumed that the introduction of the SAD in our previous generation had detrimental epigenetic effects in our current one. This article seems to clinch it. Thoughts? http://web5.cns.utexas.edu/news/2010/12/you-are-what-your-father-ate/ (more)
Someone sent me a link to this https://www.23andme.com/ancestry/origins/ -- looks interesting. Map your global origins with the most complete coverage of your DNA. 23andMe Ancestry Edition ($399) also includes: Your Relative... (more)
I don't know about the human ones, but the ones for dogs are notoriously unreliable. One lady had a champion purebred pitbull but its DNA test came back as being mostly border collie! LOL!
Was wondering what the survival advantage could have been and came across this paper: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917125/?tool=pubmed (full free text) From the abstract: "All humans are double knockouts. Humans lack the... (more)
Evolution didn't just stop with the invention of agriculture. Genetics have changed and there have been some genetic changes in response to agrarian foods. These genetic changes generally only affect a certain percentage of the population, often... (more)
Dear all! What do you think about creating the ultimate hacking thread for Apo-??4/??4 gene mutations to discuss practical real-life implications. What worked and what did not for cholesterol numbers and overall well-being in terms of lifestyle,... (more)
I thought this might be of interest to some of the folks on here. It is a free online course offered by Duke University called "Introduction to Genetics and Evolution". https://www.coursera.org/course/geneticsevolution (more)
Thanks for sharing, I will definitely sign up. Also check out http://evolvify.com/ I just found it and it's about physchology and evolution in relation to a paleo lifestyle/diet.
Women: How has a paleo diet affected your mentrual cycle?
Eating pudding and heat