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What type of knowledge about yourself would you expect to gain from a genetic test?

Answered on August 19, 2014
Created June 27, 2012 at 2:33 PM

Of all the dietary plans out there, it's the paleo system that distinguishes itself as being consistent with a rational process of ongoing learning about nutrition and self (i.e. response to a particular dietary regime). This is exemplified by the accumulating knowledge here at the Paleohacks community.

One way of learning more about oneself is via gene testing.

What type of knowledge about yourself would you expect to gain from a genetic test to help with your paleo diet?

7841848bd0c27c64353c583fb7971242

(7275)

on August 14, 2012
at 10:57 PM

Wowza, +1 for mentioning methylation. Not only should people check MTHFR, they should also check COMT, MTRR, BHMT, CBS, and BH4.

77877f762c40637911396daa19b53094

(78467)

on June 29, 2012
at 01:33 AM

Wowza, by methylation status do you mean for example the MTHFR gene or the methylation of genes (i.e. being switched on/off)

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2 Answers

2
80890193d74240cab6dda920665bfb6c

(1528)

on June 28, 2012
at 03:22 AM

Of course you want to know your APOE status. That's crucial. And you also then want to look for your methylation status - are you hypo? Hyper? Then you want to look for genes associated with obesity, diabetes, blood pressure, FH and cancer. Celiac too. Then you want to look at the genes associated with body weight, type, and BMI.

You may discover you are not what your genes might offer you - you might find yourself a little tubby, but have genes for normal BMI! This means you can improve and reach your full potential! :)

On a somber note, you have to prepare yourself should you discover you have APOE 4/4. That will require a serious life change for you and possibly your family.

77877f762c40637911396daa19b53094

(78467)

on June 29, 2012
at 01:33 AM

Wowza, by methylation status do you mean for example the MTHFR gene or the methylation of genes (i.e. being switched on/off)

7841848bd0c27c64353c583fb7971242

(7275)

on August 14, 2012
at 10:57 PM

Wowza, +1 for mentioning methylation. Not only should people check MTHFR, they should also check COMT, MTRR, BHMT, CBS, and BH4.

1
4ef079c57d2140bba4dbf4e30240a645

on June 28, 2012
at 03:03 AM

Harry funny you should ask this as just today my nutritionist (who has a PhD and is pretty picky) recommend I get this testing: https://www.pathway.com/dna-reports/pathway-fit

He is a friend and colleague so he is giving it to me at his cost, which is nice cuz its too expensive!

The reason for this test is that he thinks, genetically, I must not do well on high protein, high (healthy) fat, and low carb/vlc diet. I have been doing such a diet (pretty much a Primal diet) and CANNOT lose weight. This never ever happened before when I ate more average and a lot of grain and gluten and pasta etc..... WEIRD

Nothing else can explain it at this point except genetics. ALL other things are ruled out or accounted for (sleep, thyroid, hormones, blood glucose, insulin etc etc etc)

Im bummed cuz I was really excited about my diet.

Anyway... he says the Fit test is good and does give good info. and is based on sound science... I have not looked at it yet.

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