Livin' La Vida Low-Carb Show recently has a podcast featuring one Brian Peskin, who claims that, among other things, that getting omega-3 from fish oil is actually bad for you. Is anyone familiar with his work, and how accurate are his claims?
asked byGary_W (2718)
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on March 01, 2010
at 08:09 AM
Hmmm, came across a post by Dr. Stephan Guyenet at Whole Health Source that suggests that Peskin's claims are incorrect:
Dr. Stephan Guyenet said...
I'm familiar with Peskin. I just read his paper in Medical Hypotheses. It's time for me to put this thing to rest. He states that the fact that tumors have low oxygen supports his claim that low oxygen is behind cancer. Tumors have low oxygen because blood vessel growth doesn't keep up with tumor growth. That happens after the tumor has already developed, not beforehand.
His basic hypothesis is that polyunsaturated fats in the membrane determine the cell's permeability to oxygen. He implies that PUFA transport oxygen across the cell membrane. The problem is that oxygen doesn't require PUFA or any other fatty acid to get across the membrane. Molecular oxygen is a non-charged small molecule that diffuses across the membrane freely. His claim that PUFAs influence its transport across the membrane has no support I'm aware of. I followed his reference for that statement, which was this study:
And it didn't support his claims. As far as I can tell, the study has nothing to do with oxygen transport across the cell membrane. It's about fatty acid composition and lipid peroxidation in cancer cell lines. Grossly misquoting papers that are supposed to support your central argument is a characteristic of science abusers. A nice way to put it is that Peskin has a vivid imagination.
February 26, 2010 4:41 PM
Here's a reference showing that oxygen diffuses across the cell membrane quite readily (half as fast as through pure water, which is very fast):
From the abstract:
"It is concluded that oxygen permeation across the cell plasma membrane cannot be a rate-limiting step for cellular respiration."
February 26, 2010 4:46 PM
on March 06, 2010
at 05:22 AM
Peskin is a fraud and his ideas are nonsense.
on March 01, 2010
at 09:49 AM
Jimmy Moore isn't vetting his guests properly, and as a result is wasting everyone's time. Look at Peskin's website, it states "World's must trusted health authority". How could this possibly be correct? WAPF also has an article taking him to task http://www.westonaprice.org/Brian-Peskin-and-Essential-Fatty-Acids.html
on January 15, 2011
at 03:35 PM
The comments Dr. Kurt Harris makes after this blog post at Richard Nikoley's blog, "Free The Animal", might be of interest:
Dr. Harris posted several comments. It is useful to read all of the comments, rather than posting excerpts from those Dr. Harris wrote.
If I have it right, the main point is to reduce 6 rather than supplement 3 on top of eating a grain-fed, PUFA diet.
The standard recommendation: eat grass-fed beef and butter, and eat fish.
And on Dr. Harris' blog, Step number 6, still reads:
...Pastured (grass fed) dairy and grass fed beef or bison has a more optimal 6:3 ratio, more vitamins and CLA. A teaspoon or two of Carlson's fish oil (1-2 g DHA/EPA) daily is good compensatory supplementation if you eat grain-fed beef or no fish.
ETA: Chris Masterjohn, at Cholesterol and Health:
Cod liver oil and fish oils contain EPA, a fatty acid that is probably not essential to mammals and interferes with arachidonic acid. When the total intake of polyunsaturated fatty acids (PUFA) is low, the EPA should be efficiently converted to DHA. When total PUFA intake or EPA intake is very high, however, the EPA may interfere with arachidonic acid metabolism and contribute to deficiency symtoms such as growth retardation, dehydration, flaky and scaly skin, hair loss, gastrointestinal syndromes, or infertility. Moreover, all of the PUFA contribute to oxidative stress when consumed in high amounts, a phenomenon that contributes to heart disease, cancer, fatty liver, diabetes, brain disease, DNA damage, and ageing. Therefore, it makes sense to obtain these precious fatty acids in small amounts. This means avoiding vegetable oils and excessive supplementation with fish oils and obtaining essential fatty acids from liver, muscle meat, butter, occasional fatty fish and very small amounts of high-vitamin cod liver oil.
A recent review by Darisuh Mozaffarian of Brigham and Women's Hospital and Harvard Medical School, cited in Issue 14 of my free newsletter, concluded that the benefits from fish oils plateau at 250 mg of omega-3 fatty acids per day. This is based on studies of populations consuming far too much total PUFA and a great excess of omega-6 fatty acids, and it still only justifies the consumption of one or two servings of fatty fish per week or one-half teaspoon of high-vitamin cod liver oil per day.
Cod liver oil should thus only be consumed in amounts higher than this in order to obtain the fat-soluble vitamins, and one should only consume these higher amounts within the context of a diet rich in vitamin B6, magnesium, and other minerals, low in total PUFA, and balanced by reasonable quantities of liver, muscle meat, and butter to provide adequate arachidonic acid and prevent EPA-induced deficiency symptoms.
This is all covered in more detail in my report, How Essential Are the Essential Fatty Acids?
Hope this is of use.
on March 01, 2010
at 01:13 PM
Glad to see this cleared up.
If Stephan didn't exist, we'd have to invent him! ;)
on September 09, 2011
at 02:00 AM
Peskin is a fraud. He's a huckster and if you've been taken in by him you could do yourself a favor and Google him.
on March 07, 2011
at 07:57 PM
Even if this fellow is wrong, it's still less than ideal to have a 3/6 ratio that is so out of whack that fish oil is needed. If your primary meat source is grass-fed ruminant flesh, fish oil is unnecessary.
on March 07, 2011
at 07:33 PM
Has everyone looked up in Google the following search: "Brian Peskin Texas Attorney General Fraud."
Years ago, Peskin had a book out that touted some sort of "Essiac Tea" drink that you HAD to have in order to be healthy.
on December 20, 2010
at 01:28 AM
for me fish oil is just like olive or sunflower oils - olives and sunflower (just as fish) seeds may be alright, but oils made of them? - i guess, that that sort of extraction and refinement is among the main factors in food-related maladies and overall degeneration of 'civilized' peoples once, having succumbed to fish oil propaganda, i have bought a bottle of COD, drank it for a week or so, but then thought: "is that PALEO? - you must be kidding!"... then i threw the stuff away with no regret
on March 01, 2010
at 11:54 PM
The Omega-3's from fish oil are fine, but there does seem to be a problem with excess Vit A in cod liver oil (which has nothing to do with oxygen permeability, etc):
on May 12, 2013
at 02:28 AM
Why doesn't somebody fix these "I am a human being" tricks?
They are usually so illegible one can never use them.
on May 12, 2013
at 02:23 AM
Good question, Gary Wu; it is a pity you didn't get a good answer immediately. I trust you have learned form this, and started consulting good websites. Such blog sites are pathetic, as one can see above. Ignoramuses who know nothing about the topic, start flaunting their two cents and tooting their arrogant horns, rapidly forming a virtual lynch mob, simply because they are set in their ways and can�t learn.
Just heard Brian Peskin on C2C and the internet. We were amazed by his brilliance and, especially, appreciate his engineering background, the root of his honesty and integrity. Engineers are serious scientists, who secure their work by a factor of ten; they live by facts, not theories or politics. He gave several interesting nutritional facts; but, hopefully, you actually read his work years ago.
P.S.: What close-minded kind of people use this site, anyway? Everyone supporting Peskin gets negative votes!
on April 14, 2013
at 02:26 AM
It wouldn't hurt to read an article by Ray Peat on fish oils before you assume just because Peskin is a fraud, fish oil is automatically healthy to consume.
on May 10, 2013
at 01:08 PM
doesn't the China-Cornell-Oxford Project support what Dr Peskin is saying?
the more animal protein you eat the higher your risk of cancer, if you don't want cancer keep the level of animal protein in your diet under 5%
on April 14, 2013
at 01:07 AM
I was looking for even more info on Brian Peskin, and I saw this thread.
Dr. Guyenet said:
"His basic hypothesis is that polyunsaturated fats in the membrane determine the cell's permeability to oxygen."
Peskin never said that. He is referring to adulterated oils. You know--the crap in restaurant and in our packaged and canned goods we get at the store.
And, yes, it does affect the oxygen level in our cells.
Dr. Guyenet said:
"He implies that PUFA transport oxygen across the cell membrane."
He neither said it or implied it. He said that the bad oils cannot transport enough of the oxygen.
I don't believe everything Peskin says, but a lot of what he says does make sense.
on January 15, 2011
at 06:27 AM
Thank you Harry S Aust. There is a growing list of MD's and PHD's that have found Professor Brian Peskin's research to be life changing.
His peered reviewed paper on Why Statins don't work is a masterpiece. They put a team of PHD, MD Biochemists on Professor Peskin to refute his paper on Statins and they COULDN'T. The director then said that Professor Peskin's paper was far too important not to published, SO THEY PUBLISHED IT!!!!!!!! That was the first peer reviewed paper of it's kind on Statins to get published. It takes a lot of competence to refute a team of PHD, MD biochemists on the issue of Statins. Professor Brian Peskin held his ground and did that. THAT PEERED REVIEW PAPER WILL SAVE LIVES. Despite what the pharmaceutical industry sponsored website "Quackwatch" says, Professor Brian Peskin is certainly not a quack.
On the fish oil issue, in science, the goal is not to prove a hypothesis but to FALSIFY IT. If the hypothesis cannot be falsified then the hypothesis may be valid. Like one scientist said "If you tell me that all Swans are white, then I better not find any black Swans." Professor Brian Peskin has shown a series of tightly controlled SCIENTIC EXPERIMENTS, NOT STUDIES, FALSIFYING "the fish oil is good for you" hypothesis. Observational studies show only associations are weak and useless. Tightly controlled scientific experiments show cause and effect and are extremely powerful and VALID. You can try to "prove" that fish oil is good for you all you want. (White Swans) There is a mountain of science that has already FALSIFIED the "Fish oil is good for you" hypothesis. (Black Swans) Fish oil is the New "Symbolic Margarine".
Lastly, Professor Brian Peskin's book, "The Hidden Story of Cancer". The first thing that blew me away was the sheer number of accolades from MD's and PHD's. I HAVE NEVER SEEN ANYTHING LIKE THIS FROM A BOOK OF THIS NATURE. (http://www.brianpeskin.com/BP.com/accolades/Accolades-HS.pdf)
Here's a few examples:
???I had been taking high-dose fish oil for many years in an attempt to prevent C-V disease and retard inflammation. However, I noticed that my fasting blood sugars were always in the high range (100-115) and measurements of oxidative stress also reflected high levels. No one could explain it since my hemoglobin a1c always stayed low. Since switching to the parent EFAs (PEOs), as recommended in The Hidden Story of Cancer, my FBS came down to 84. My lipids also looked better than ever. I think many of our colleagues do not appreciate the dangers of high dose fish oil. Derivative EFAs like fish oil easily oxidize, and although some surrogate markers may improve, the final cost is still unknown. Thanks so very much for your book.??? ???Ira L. Goodman, M.D., Ophthalmic Surgeon (retired), Holistic Medicine
???To save your health and your life you must read this book. This information has transformed me, my practice and my patients. I have followed the information on essential fats for the past 25 years, but my patients did not see the results that the researchers reported. The discovery in this book makes sense and finally patients are reporting improvements. I hope other physicians will become aware of this groundbreaking information.??? ???Abram Ber , M.D., Homeopathic Physician/Preventive Medicine, Scottsdale, AZ
???Impeccable research and novel insights of sheer genius. Brian???s accomplishment is singular???no groups, no public money, only elegant science showing how proper use of EFAs is the missing link for practical application of Otto Warburg???s discovery. This knowledge is priceless for your future health.??? ???Brian N. Vonk, M.D., Board certified: Internist, Cardiologist, Radiologist, Norfolk, NB
???I bought your magnificent book a few weeks ago and I couldn???t stop reading it! It is well written and easy to read. As a scientist in the heart regeneration field in Boston, Massachusetts, I really believe you have done a great job encapsulating, integrating and advancing the huge amount of data in the field of cancer and related topics. It was almost impossible to do, but you did it!??????Serge Gregoire, Ph.D., Massachusetts General Hospital (Harvard), Boston, MA
???In the last ninety-three years, there have been only two monumental works that have succeeded in explaining the actual cause and treatment of cancer: No. 1 is the Nobel Prizewinning German physician and scientist, Otto Warburg, M.D., Ph.D. work, The Metabolism of Tumours, published in Germany in1910. No. 2 is Professor Brian Scott Peskin???s The Hidden Story of Cancer, which details a scientific breakthrough that explains Dr. Warburg???s research and introduces new science that will prevent cancer. This is undoubtedly a breakthrough of biblical proportions.??? ???Bernardo C. Majalca, N.D. Stage Four Cancer Researcher & Consultant, San Diego, CA
???We are honored to have Professor Peskin as a member of the faculty. His nutritional discoveries and practical applications through Life-Systems Engineering [Science] are unprecedented.??? ???Dr. James Douglas, President, Texas Southern University (1998-1999)
OF COURSE, ALL THESE PHD'S AND MD'S CAN BE CONTACTED.
This growing list of PHD's and MD's have one thing in common that the "Haters" don't, THEY ACTUALLY READ THE BOOK.
on November 29, 2011
at 12:18 AM
Dr. Kurt Harris is a FRAUD, and an arrogant son of a bitch too. ....... He thinks he is H O T S H I T but is nothing but a COLD TURD.
Dr. Kurt Harris bought penile enlargment devices from Drs. Morgan Freeman and Bruce Lee in the mountains of Panama for a reasonable price.
on September 10, 2011
at 08:08 PM
Uh, I am reading the book now from Peskin but you all need to re read sid_aust's post. He and his wife both HAD CANCER, *AS IN NO LONGER HAVE CANCER!!!!*That pretty much sums up the Peskin is full of baloney issue. As far as fish oil being bad for you, when did you grow up, as in what era? When I was a boy, every day, my mother and everyone's mother I knew forced them to take a spoonful of cod liver oil daily. Most of my friends are dead now from cancer. Not that that had anything whatsoever to do with it but if it was suppose to help, it certainly didn't help anyone I knew. Now I also Googled Peskin and read the fraud documents and as was mentioned earlier, follow the money, who pays the bills on the quackwatch site that Dr. Stephan Guyernet writes for? Its all about money!! Cancer was cured years ago, but no money in natural cures. Big Pharma equals death to any non profit cure for anything!Fraud claim was issued for Peskin stating that the diet he recommended would prevent cancer and heart disease, you just cant make claims like that without upsetting the Big Pharma folks!!Sorry, that's a no no!!!He is fortunate he was only sued and not whacked!! I think you need to be intelligent and look at the research, as I am doing now. I am not supporting Peskin personally at this point either, but if Big Pharma is against, I am much more likely to consider his research, which by the way is based off of Nobel Prize winner Otto Warburg, M.D., Ph.D's research. You should probably take a look at both before you yell Quack! End of Rant
on December 19, 2010
at 02:26 PM
Brian Peskin is right on.. A lot of his work comes directly from medical school textbook in Biochemtry and Physiology...He has always said he is just the messenger. He has never been proven wrong. Unless you have completley read all of his work I don't think anyone can make intelligent conversation...without first reading his work..I had colon cancer and wife had breast and this is the best thing I have ever put to use in my life. I have studied his work for the past 2 years and have talked with him and have exchanged emailed many times.. He say the most letted individual have a lot of trouble with his work because they are so entrenched in what they were talk...They don't like anyone outside the profession they are wrong and neigher would you or I...I take cancer extremely seriously and is not something I take lightly...I got permission from Brian Peskin to write a resource based on his book with all the links charts, articles for anyone to further study his work...I give it away for free...and is is 72 pages...if anyone is interested I will be glad to send it to them...not selling a thing..this research needs to be out there for all to see... thanks email@example.com