What does fat do?

Answered on September 12, 2014
Created January 07, 2011 at 3:32 PM

So, I understand how carbs elicit an insulin response and protein, a glucagon response; but what about fat? I've heard it's more or less neutral but it's got to do something, right? Fat doesn't elicit any hormone?


on January 08, 2011
at 01:08 AM

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7 Answers



on January 08, 2011
at 07:11 PM

From the book Protein Power, by the Eades, comes this graph that explains the influence of certain types of food on the hormones insulin and glucagon:

Type of Food ---------------- Insulin ---------- Glucagon

  • Carbohydrate ----------- increase --------- no change
  • Protein --------------- slight increase ---- slight increase
  • Fat ----------------------- no change -------- no change

This graph is on page 37.

You might also be interested in Mark Sisson's posts on fat.

  1. The Definitive Guide to Fats
  2. The Definitive Guide to Saturated Fat
  3. Mmmmmmmmmmmm??? Fat

Here's a great quote about fat from the last one:

"...according to a group of UC Irvine pharmacologists, unsaturated fats foster satiety and curb hunger. They do so by triggering production of a certain compound in the small intestine that basically tells our bodies we???re full. Oleic acid, a fatty acid derived from certain fats, begins production of oleoylethanolamide (OEA) which gets absorbed into nerve endings. The nerve endings shoot off the ???all done!??? message to the brain..."

Hope this helps!


on January 08, 2011
at 04:57 AM

According to Dr. Ron Rosedale, fat is the one macro nutrient that actually lowers leptin. By lowering the leptin signal, you become more sensitive to it. He believes that 90% of all nutrition is in eating the right fats. He is also not against SAT fat. Only in the first 3 weeks does he restrict it. He wants you to start to burn your own SAT fat on your body first. He believes that GHee and Coconut, both mainly MCTs are the best for burning. Once you are efficient in being a fat burner, enjoy the SAT fat. He puts cheese on steak!


on January 08, 2011
at 01:43 AM

It's too late in the day for me to write much. I apologize for being brief.

Adipose tissue is an endocrine organ.

Here are two basic primers with links to more information.



Wikipedia is not the best, but, it is a place to start. The "good stuff" is usually in the references and links at the bottom of the pages.

Hope this helps a bit. At least to give you a start.



on January 08, 2011
at 10:07 PM

as far as i understand, fats 'elicit' production of ASP, which in its turn 'takes' them (dietary lipids) directly into adipocites, i.e. fats is the ultimate energy storage macronutrient - store it first, burn it later though, i personally am still confused as to how different kinds of fats get metabolized: there was something about MCTs which made them to 'burned' asap, or?...



on January 07, 2011
at 04:54 PM

Leptin is somewhat based on bodyfat rather than ingested fat. But mostly it's overall calories and carbs in the diet.

Cholecystokinin might be fat dependant. But yeah, fat looks neutral for hormonal releases.


on January 07, 2011
at 03:58 PM

As far as I understand it, all food consumption releases some amount of insulin, but for fat this is negligible as compared to carbohydrates. So for all practical purposes, fat is hormone neutral.

It may cause some leptin release? Does anyone know?



on January 07, 2011
at 11:54 PM

Yes it is the white adipose tissue (fat cells) that releases leptin, as well as stomach lining. I'm not sure about any hormonal release.

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