About a year ago I ran across an article (e.g. pubmed or paleo blog) or study that discussed some mice that starved to death while remaining obese. Their bodies "refused" to give up the fat. I cannot find this study and I'm wondering if anyone else knows of it or remembers the mechanism?
I'm in a similar situation. Regardless of calories (isocaloric or hypocaloric) or moderate or ketogenic calorie intake, my body does not want to give up its fat no matter what combo I choose. I've been trying for months and my waistline is always the same. I'm looking for material that covers the following topics:
1. Reasons the body will not give up fat
2. Strategies to get the body to upregulate fat burning rather than muscle
Background: I've been strict Paleo and it never seems to matter. My lipids are near-perfect and continue to get better but the fat does not budge. [Edit: My Thyroid panel is fine too.] I used to be able to effortlessly lose bodyfat easily by dropping my calories, but that no longer works. WTF is going on? I feel like the rats from the afformentioned study.
asked byJustin_Reinhart_GP (0)
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on September 15, 2014
at 11:34 PM
"1. Reasons the body will not give up fat"
Toxins are often stored in adipose tissue. There is a study that found humans with platic-like substances in their adipose tissue, and the substance increased in the blood when they lost weight. Maybe weight gain is really mostly about removing excess toxins from the blood and storing them in adipose tissue, to be released later when hopefully the body is in a better shape. I would work on things that help the body get rid of toxins. That's a huge research topic though, I think there is evidence MCT oil is good at protecting the liver from some toxins, such as endotoxin.
on September 16, 2014
at 07:02 AM
In 1981, M.R.C. Greenwood reported that if she restricted the diet of an obese strain of rats known as Zucker rats… and did it from birth onward, these rats would actually grow fatter by adulthood than their littermates who were allowed to eat to their hearts’ content. Clearly, the number of calories these rats consumed over the course of their life was not the critical factor in their obesity (unless we are prepared to argue that eating fewer calories induces greater obesity)… these semi-starved Zucker rats had 50% less muscle mass than genetically lean rats, and 30% less muscle mass than the Zucker rats that ate as much as they wanted. They, too, were sacrificing their muscles and organs to make fat.”
Google the author & take a look at her work on PubMed