5

votes

Does fatty liver prevent loss of bodyfat even with paleo?

Answered on August 19, 2014
Created July 07, 2012 at 9:24 PM

I have been doing low carb Paleo and intermittent fasting the last few months to help reduce bodyfat and eliminate non-alcoholic fatty liver (NAFLD). While I have lost about 7 lbs. and about 5% in bodyfat, I have a long ways to go. In addition, my latest lipids (TC, LDL, TRIGS) increased in just 3 months. I do not have cravings and feel ok on the diet and doing as much as a 20 hr. fast and 4-hr refeed. I only consume carbs after workouts and no more than 75g total. Fruits are low glycemic and limited to no more than 15g fructose. I figure I need just enough carbs to help maintain thyroid hormone output.

Would I be correct to assume that until the NAFLD resolves, it will be very difficult to get my bodyfat down much further?

E753cf7753e7be889ca68b1a4203483f

(722)

on September 09, 2012
at 09:56 PM

Intra Abdomial, the gut!

72cd359efb959175e2c7786ea0450879

(68)

on July 10, 2012
at 08:43 PM

what is "IA" fatty tissue???

E753cf7753e7be889ca68b1a4203483f

(722)

on July 09, 2012
at 10:00 PM

You could very well be correct and my thought was that the changes reported weren't large enough to matter much anyway. If the numbers were extreme, then maybe something needed to be changed!

3846a3b61bc9051e4baebdef62e58c52

(18635)

on July 08, 2012
at 04:34 PM

I've heard of these numbers getting worse while the liver heals and as you lose weight. I'd wait 6 months or more before retesting.

B9d1554c3778a2197fe6d89c2d627154

(35)

on July 08, 2012
at 05:59 AM

Never heard this with IF, only from fasting longer than 25 hours which I don't do.

3bad4b0b105bf44d7650e7fdfbe15cbd

(860)

on July 08, 2012
at 02:26 AM

Your changes the last measurement are somewhat alarming. Everything seems to have gotten worse. Perhaps fasting isn't right for you? Anecdotally, I've read that some people see improvements with fasting while others see deterioration. You may want to stop the fasting since everything was moving in the right direction before it.

3846a3b61bc9051e4baebdef62e58c52

(18635)

on July 07, 2012
at 11:20 PM

I don't think your lipid numbers are relevant. They will be skewed while your losing weight anyhow. How in the world is this relevant?

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6 Answers

3
E753cf7753e7be889ca68b1a4203483f

on July 07, 2012
at 10:23 PM

Your fatty liver shouldn't prevent your fat loss. Fatty liver correlates with IA fatty tissue, to the best of my current knowledge. That's the "bad" kind of body fat, but if you are looking for weight loss, it's the "good" kind, since it's easier to loose. Fatty liver can by the way be caused by other factors as well. Regarding your lipids, it would give us valuable information if you post some numbers.

E753cf7753e7be889ca68b1a4203483f

(722)

on September 09, 2012
at 09:56 PM

Intra Abdomial, the gut!

3846a3b61bc9051e4baebdef62e58c52

(18635)

on July 07, 2012
at 11:20 PM

I don't think your lipid numbers are relevant. They will be skewed while your losing weight anyhow. How in the world is this relevant?

E753cf7753e7be889ca68b1a4203483f

(722)

on July 09, 2012
at 10:00 PM

You could very well be correct and my thought was that the changes reported weren't large enough to matter much anyway. If the numbers were extreme, then maybe something needed to be changed!

72cd359efb959175e2c7786ea0450879

(68)

on July 10, 2012
at 08:43 PM

what is "IA" fatty tissue???

2
3846a3b61bc9051e4baebdef62e58c52

(18635)

on July 07, 2012
at 11:22 PM

I think you would be correct in assuming that NAFLD could inhibit your weight loss. The liver has many functions in the metabolic chain and until its healthy and functioning well it is safe to say that your progress may be hindered. It is good that you are keeping your fructose low and hopefully doing some exercise. Just keep with it and let the healing take place. It didn't happen overnight and it wont resolve overnight. Good health!

1
B9d1554c3778a2197fe6d89c2d627154

on July 08, 2012
at 01:26 AM

Here are my lipid levels

PRIOR TO LC PALEO & IF: 06-11: TC: 163 LDL:92 HDL:42 TRIG: 147 HGBA1C: 5.6 INSULIN: 2.3

AFTER STARTING LC PALEO: 10-11: TC: 214 LDL: 144 HDL: 47 TRIG: 113 HGBA1C: 5.3 INSULIN: <2.0

AFTER STARTING LC PALEO/JUST STARTED IF: 03-12: TC: 197 LDL: 132 HDL: 43 TRIG: 108 HGBA1C: 5.0 INSULIN:<2.0

3 mos. AFTER STARTING LC PALEO/JUST STARTED IF: 06-12: TC: 235 LDL: 169 HDL: 36 TRIG: 155 HGBA1C: 5.8 INSULIN: 5.2

3bad4b0b105bf44d7650e7fdfbe15cbd

(860)

on July 08, 2012
at 02:26 AM

Your changes the last measurement are somewhat alarming. Everything seems to have gotten worse. Perhaps fasting isn't right for you? Anecdotally, I've read that some people see improvements with fasting while others see deterioration. You may want to stop the fasting since everything was moving in the right direction before it.

B9d1554c3778a2197fe6d89c2d627154

(35)

on July 08, 2012
at 05:59 AM

Never heard this with IF, only from fasting longer than 25 hours which I don't do.

3846a3b61bc9051e4baebdef62e58c52

(18635)

on July 08, 2012
at 04:34 PM

I've heard of these numbers getting worse while the liver heals and as you lose weight. I'd wait 6 months or more before retesting.

0
1d9af5db8833413037be3ac48964714f

on July 08, 2012
at 12:02 PM

Sounds like you've done your research and you are on the right track.

0
B9d1554c3778a2197fe6d89c2d627154

on July 08, 2012
at 05:53 AM

It's easy to say that fasting isn't working or that I have metabolic syndrome, but neither make any #$%ing sense given my regimen and diet. I have cut carbs; I already drink nothing but water, sometimes with a little stevia; I resistance train 4 x's a week, interval cardio 2-3 x's/week. I've already had my RMR tested at the local university and it is on the FAST end.

So, the only thing that I can make sense is this:

Chris Kresser had Chris Masterjohn on his podcast yesterday, and they covered reasons why cholesterol would increase after going paleo, and why it may not be bad. My hopes are that this is the reason for the increase:

http://chriskresser.com/chris-masterjohn-on-cholesterol-and-heart-disease-part-3

Masterjohn mentioned that a transitory increased blood lipids could be a sign that fatty liver disease is being reversed.

Highlights:

*So, the first thing that we need to understand is that there are good reasons and bad reasons for increases in cholesterol in the blood. So, one of the reasons that cholesterol can increase is if we’re clearing lipids from the liver. Let’s say, for example, that a person has nonalcoholic fatty liver disease and they start resolving it. Well, one of the key problems with fatty liver disease is that the lipids get stuck in the liver and they’re not being released into the bloodstream, so once you start clearing that, part of what may happen is you may get an increase in triglycerides, and you may get an increase in cholesterol in the blood. And that is a good thing because nonalcoholic fatty liver disease is not only very dangerous for the liver, but it’s actually a much stronger predictor of cardiovascular disease risk.

Chris Masterjohn: So, clearing lipids from the liver is good. You can have a decreased clearing of lipids into atherosclerotic plaques, and that’s also going to be good. You can have increased weight loss. And weight loss, if you’re clearing lipids from adipose stores, that could elevate your blood lipids, and this could be good or it could have negative effects in some cases. You know, if you have an overweight person, they are a lot more likely to have fatty liver, they are a lot more likely to have insulin resistance, but probably the person who’s probably in the worst-case scenario is the overweight person who is trying to lose weight by restricting calories and is in a sort of chronic starvation mode, where instead of getting a good diet that’s lowering their set-point, they’re always operating underneath their set-point, and that can contribute to a lot of stress and release of free fatty acids and things that can have negative effects on thyroid hormone. But I think if you follow a weight loss strategy that is not leaving you hungry and stressed, I think you can expect a moderate elevation of lipids in some scenarios. And we talked about this in the second episode, so we shouldn’t go into too much detail; but in my opinion, if someone is losing weight and they’re losing it at a healthy pace in a sustainable way and they see fluctuations in their blood lipids, in my personal opinion, they should wait until their weight has been stable for three to six months before trying to interpret it. In other words, if blood lipids go up while you’re losing weight, concentrate on losing the weight and normalizing your metabolism. Then once your weight has been stable, start looking at blood lipids and so on.

I also upped my dose of CHOLINE a month before the most recent test: "what you were just talking about in terms of switching to a Primal/Paleo type of diet and the lipids going up because the fatty liver is sort of unpacking itself. And you’ve written about this extensively that choline is one of the nutrients that makes that possible, so can you say a little bit more about that?

...it’s very likely that if you do have fatty liver you are going to contribute to its resolution, because choline is the key nutrient that is needed to package the fats in the liver and export them into the bloodstream so they can be metabolized by other tissues.

...if someone is losing weight and they’re losing it at a healthy pace in a sustainable way and they see fluctuations in their blood lipids, in my personal opinion, they should wait until their weight has been stable for three to six months before trying to interpret it. In other words, if blood lipids go up while you’re losing weight, concentrate on losing the weight and normalizing your metabolism. Then once your weight has been stable, start looking at blood lipids and so on. " "I think you can assume that resolution of fatty liver is a very likely candidate reason for why blood lipids may increase, but they should normalize over time.*

0
1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on July 08, 2012
at 02:51 AM

You have Metobolic Syndrome. It may take some time to reverse. I would consider eating Paleo but removing all liquids except water (Unless you have some fermented something you would like to drink).

I would also consider getting a new leaf assesment and a Polar Heart Rate Monitor. The exercise routine from NewLeaf is super helpful to a lot of people.

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