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Low-Fat Diet With Fish Oil Supplements Slows Growth Rate Of Prostate Cancer Cells?

Answered on August 19, 2014
Created October 28, 2011 at 5:53 PM

I came across this article today and wanted to know what you all thought about it. If I was the average American reading this, I would probably be inclined to lead toward a low-fat diet. What would you say to that person after they read this article?

http://www.medicalnewstoday.com/articles/236755.php

00c8eb3f6e6a1884216044ca29cf868a

on October 29, 2011
at 03:24 AM

Wheat flour is about 1.7% PUFA by calories, which is roughly the same as coconut oil (1.8% PUFA). http://nutritiondata.self.com/facts/cereal-grains-and-pasta/5747/2 Corn is roughly 5.3% PUFA by calories, which is greater than grain-fed beef tallow (3.7%). http://nutritiondata.self.com/facts/cereal-grains-and-pasta/5687/2

E5c7f14800c5992831f5c70fa746dc5c

(12857)

on October 28, 2011
at 10:30 PM

Most fats come with a decent amount of pufas though even the most saturated/monounsaturated ones. If your goal is lowest amount of pufas you can't get lower than using carbs as your main calorie source.

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2 Answers

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00c8eb3f6e6a1884216044ca29cf868a

on October 28, 2011
at 09:44 PM

"in men that ate a low-fat diet together with fish oil supplements for four to six weeks before prostate removal compared to men who ate a Western diet high in fat."

From the actual study:

"Patients undergoing radical prostatectomy were randomly assigned to receive a low-fat diet with 5 grams of fish oil daily (dietary omega-6:omega-3 ratio of 2:1) or a control Western diet (omega-6:omega-3 ratio of 15:1) for four to six weeks prior to surgery." http://www.ncbi.nlm.nih.gov/pubmed/22027686

In other words, there's no group for "men who ate a low-fat diet without fish oil supplementation" or for "men who supplemented fish oil while maintaining normal fat intake", and we cannot say which of the two interventions made the difference based on this study alone.

Also note that one can also achieve a lower n-6:n-3 ratio by replacing PUFA with saturated or monounsaturated fat, instead of carbs.

File this under "how to get the results you want".

JS

E5c7f14800c5992831f5c70fa746dc5c

(12857)

on October 28, 2011
at 10:30 PM

Most fats come with a decent amount of pufas though even the most saturated/monounsaturated ones. If your goal is lowest amount of pufas you can't get lower than using carbs as your main calorie source.

00c8eb3f6e6a1884216044ca29cf868a

on October 29, 2011
at 03:24 AM

Wheat flour is about 1.7% PUFA by calories, which is roughly the same as coconut oil (1.8% PUFA). http://nutritiondata.self.com/facts/cereal-grains-and-pasta/5747/2 Corn is roughly 5.3% PUFA by calories, which is greater than grain-fed beef tallow (3.7%). http://nutritiondata.self.com/facts/cereal-grains-and-pasta/5687/2

2
77877f762c40637911396daa19b53094

(78467)

on October 28, 2011
at 06:55 PM

I would tell them that the press 99% of the time gets health info WRONG. So don't trust the "facts" of the article, but go look at the actual study before judging anything.

Having said that (and not caring enough to look at the actual study, if I can find it), in this instance, a ketogenic paleo diet would have probably been much better.

But in any case, this diet worked because they drastically lowered O6 levels (they reduced ALL fat so of course, they would have reduced the excessive O6 levels causing inflammation) and substituted with O3 oils.

We know that cancer feeds off of sugar, and a ketogenic diet reduces the fuel that cancer needs. We also know that a paleo diet reverses inflammation by lowering O6 levels and increasing O3 levels.

I can only imagine how much better the outcome would have been in this study using a Ketogenic Paleo diet.

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