Have any of the of the paleo "heavy-weights" / drs or research ever tackled Dupuytren???s contracture vs diet? If so, would you be so kind in sharing the links.
I've read anecdotal accounts of the potential linkage between each of (of combination of) celiac disease, diabetes, high blood levels of glucose-insulin, and Dupuytren???s contracture. I've also read of anecdotal linkages and/or conjecture between DC and autoimmune diseases / inflammation. However, I'm looking for real data / analysis (if there is any).
That said, and to further the anecdotal cases, anybody here have Dupuytren???s contracture and also suffer(ed) from celiac disease or diabetes? How about auto immune diseases and Dupuytren???s contracture?
asked bykingchimp (270)
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on August 22, 2013
at 01:51 PM
Try pubmed, something like this: http://www.ncbi.nlm.nih.gov/pubmed/?term=Dupuytren's+co-morbidity
This hit: http://www.ncbi.nlm.nih.gov/pubmed/21803632 talks about the HLA-DRB1*15 allele
That's the one that shows up with the autoimmune issues you mentioned. http://immunogenetics.blogspot.ca/2012/01/hla-and-autoimmune-disease-association.html http://en.wikipedia.org/wiki/HLA-DR15
on March 17, 2013
at 02:30 PM
There's a definite relationship between Dupuytren's and high blood sugar levels such as happen in poorly regulated diabetes. I have never heard of a link to coeliac disease or any auto-immune condition. http://dupuytrens-society.org.uk/Dupuytrens.html This is our information page in case youwant to know about any other conditions.
on March 12, 2013
at 11:00 PM
My Uncle has this and is diabetic. My Father in law has this and also suffers from vitiligo, gout and thyroid problems. Not heard of any evidence of a connection though.
on March 12, 2013
at 10:23 PM
Nice question! Both my parents have this so it looks like I'll be getting it in due course (I believe it's genetic?) Would be nice to know if there's something I can do to prevent/reduce it.