5

votes

Cancer best diet

Answered on December 11, 2014
Created June 03, 2012 at 9:20 AM

With Relay for life going on today in our neighborhood. Could we come up with best practices for diet with regards to cancer?

Avoid sugar, etc...

94480caec9fbbaacc386d86a45efa720

(1007)

on June 09, 2012
at 06:10 PM

Jaminet is also saying regarding blood glucose levels that "The 20% carb diet lines up pretty well with the mortality minimum, and both high-carb and very low-carb diets wind up at bins with slightly elevated mortality" read here: http://perfecthealthdiet.com/2011/11/safe-starches-symposium-dr-ron-rosedale/ Having recently had a breast cancer tumor removed and facing chemo and hormone treatment, I'm reconsidering my low-carb diet - though it has definitely helped me get down to a normal weight which is good for my overall prognosis. I'm new to info on blood glucose ad IGF-1 so thanks for comm

A2c38be4c54c91a15071f82f14cac0b3

(12682)

on June 04, 2012
at 09:15 PM

Nice, thanks Jay. A lot of variables were at play in the Lyon study in addition to lower linoleic acid intake of course, but it certainly doesn't refute the theory.

4781cf8ae1bfcb558dfb056af17bea94

(4359)

on June 04, 2012
at 08:19 PM

And don't forget the Lyon Diet Heart Study. The cancer endpoint write up is here: http://archinte.jamanetwork.com/article.aspx?volume=158&issue=11&page=1181

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on June 04, 2012
at 04:44 AM

In the situation I would not eat sugar of any kind or starches. I might eat raspberries and blueberries on ocassion. That would be it.

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on June 04, 2012
at 04:43 AM

In the situation I would need eat sugar of any kind or starches. I might eat raspberries and blueberries on ocassion. That would be it.

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on June 04, 2012
at 01:34 AM

Very Nice Mscott!

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on June 03, 2012
at 04:23 PM

I would say no vegetable oil, soy (or other estrogenic substances), but would never say no sugar or dairy, especially if the sugar comes from fruit. Cancer does feed on sugar, but that doesn't make sugar evil (since cancer feeds on protein too). It's like saying starch is a slow sugar because it has to be broken down to glucose first.

782d92f4127823bdfb2ddfcbcf961d0e

(5231)

on June 03, 2012
at 04:09 PM

CLA = conjugated linoleic acid, found in grass-fed butter and meats.

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on June 03, 2012
at 04:00 PM

PUFAs are huge. Avoid Vegetable oil for sure. I would eat wild salmon twice a week as my exception though. I could be wrong on that. But I would do it personally.

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on June 03, 2012
at 03:58 PM

I would say no sugar, dairy, vegetable oil, soy.

276a5e631b62f8e0793987c0496364bb

(1644)

on June 03, 2012
at 03:55 PM

Vegetable/seed oils, yes. Pork is pretty omega-6-y, too.

510bdda8988ed0d4b0ec0b738b4edb73

(20898)

on June 03, 2012
at 03:18 PM

My doctors told me that too. I'm really mad they did. They think that calories matter more than anything else. But cancer feeds on sugar and a keto diet is much more effective than eating sugar and feeding the cancer at the same time as trying to kill it.

F5a0ddffcf9ef5beca864050f090a790

(15515)

on June 03, 2012
at 02:55 PM

What is CLA? 03 is omega 3, right?

F5a0ddffcf9ef5beca864050f090a790

(15515)

on June 03, 2012
at 02:54 PM

So PUFAs are nuts and oils, right?

F5a0ddffcf9ef5beca864050f090a790

(15515)

on June 03, 2012
at 02:53 PM

@ Korion - I don't know what to do. Sugar or not? Can you guys agree and tell me what you think? By the way, if I eat ice-cream with sugar, does it count as sugar?

Bf57bcbdc19d4f1728599053acd020ab

(5043)

on June 03, 2012
at 12:27 PM

cancer feeds off sugar. Not a good idea. There's a lot of evidence out there with regards to this, if you dig a little.

5e92edc5a180787a60a252a8232006e9

(345)

on June 03, 2012
at 10:53 AM

I agree with this and Gary Taubes spoke the same about sugar being the driving force behind oncogenesis. But shouldn't the focus really be on insulin instead? Sugar increases insulin. But it's not jsut sugar that will massively release insulin. Casein and dairy, for example, could release insulin but not necessarily increase BG. Hence focus on IGF-1, etc. to limit cancer.

956bcad1d462d433a4e1e22f6e3355d5

(1191)

on June 03, 2012
at 10:50 AM

Guess he's being ironic

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on June 03, 2012
at 10:35 AM

Lol, VB, didn't you said Ray Peat makes no sense? Suddenly buying sugar?

F5a0ddffcf9ef5beca864050f090a790

(15515)

on June 03, 2012
at 10:19 AM

I am going to get some sugar today. My mom is a cancer survivor and she eats everything - gluten, meat, smoked things, sweets.

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6 Answers

7
B3173217a49b5b0116078775a17eb21d

(11488)

on June 03, 2012
at 10:21 AM

One that prevents hyperglycemia.

Since cancer cells can't typically burn fat, they depend on glucose for their energy supply, the Warburg Effect ( http://en.wikipedia.org/wiki/Warburg_effect ). If you have high blood glucose levels then you are potentially feeding the cancer cells.

Jaminet has this to say: "Higher blood glucose levels provide more fuel to tumour cells, stimulate their proliferation and hasten the progression of the cancer. If high blood glucose induces cells to start burning glucose, it may actually cause cancer by switching them from normal metabolism to tumour cell metabolism."

Some of this is obviously speculation, but it seems like a sensible explanation given that cancer is a "disease of civilisation", which is especially prevalant in our "55% energy from carb" society.

So cutting carbs (and preventing hyperglycemia) might be beneficial. Cutting them further and inducing ketosis might have an even stronger preventative influence on cancer.

Jaminet again: "In contrast, ketogenic diets which keep blood glucose levels low and provide ketone bodies to mitochondria have shown remarkable effectiveness in slowing cancer progression. In vitro, ketone bodies have been shown sometimes to restore mitochondria to health, triggering cancer cell death. Ketogenic diets have been shon in clinical trials to slow the progress of brain cancer, and clinical trials of other cancers are in progress."

Jaminet suggests a low-carb, low-protein, ketogenic day once a week as a hedge answer cancer.

5e92edc5a180787a60a252a8232006e9

(345)

on June 03, 2012
at 10:53 AM

I agree with this and Gary Taubes spoke the same about sugar being the driving force behind oncogenesis. But shouldn't the focus really be on insulin instead? Sugar increases insulin. But it's not jsut sugar that will massively release insulin. Casein and dairy, for example, could release insulin but not necessarily increase BG. Hence focus on IGF-1, etc. to limit cancer.

94480caec9fbbaacc386d86a45efa720

(1007)

on June 09, 2012
at 06:10 PM

Jaminet is also saying regarding blood glucose levels that "The 20% carb diet lines up pretty well with the mortality minimum, and both high-carb and very low-carb diets wind up at bins with slightly elevated mortality" read here: http://perfecthealthdiet.com/2011/11/safe-starches-symposium-dr-ron-rosedale/ Having recently had a breast cancer tumor removed and facing chemo and hormone treatment, I'm reconsidering my low-carb diet - though it has definitely helped me get down to a normal weight which is good for my overall prognosis. I'm new to info on blood glucose ad IGF-1 so thanks for comm

6
A2c38be4c54c91a15071f82f14cac0b3

(12682)

on June 03, 2012
at 11:30 PM

A few answers have said that avoidance of PUFAs is important. I don't advocate sucking down fish oil, but I think avoidance of linoleic acid is the important part, not avoidance of all PUFA's. I think linoleic acid is a strong promoter of cancer.

Korion cited this study involving rats red different oils and given the carcinogen dimethylbenz(a)anthracene. The authors stated "Mammary tumorigenesis was very sensitive to linoleate intake".

In this study, rats were fed corn oil, coconut oil, and a fish oil and exposed to a carcinogen that induces mammary tumors. The fish oil and coconut oil resulted in the same amount of mammary tumors, while the corn oil produced significantly more tumors. The authors stated "The protective effect of menhaden oil and coconut oil may be due, at least in part, to the decreased linoleic acid content of these diets relative to the corn oil diet".

In a study in which rats injected with the carcinogen azoxymethane, rats fed corn oil and safflower oil (high in linoleic acid) had increased numbers of colon tumors, while rats fed coconut oil, olive oil, and MCT oil (low in linoleic acid) did not.

In another study in which rats were fed sunflower, rapeseed, olive, and coconut oil, the authors wrote "Our results indicate that a high linoleic acid diet may contribute to oxidative stress in the liver of female rats leading to a marginal increase in oxidative DNA-damage".

In perhaps my favorite of these studies, rats were fed corn, olive, coconut, and safflower and cancer was initiated using N-nitrosomethylurea. There was a direct correlation between the linoleic acid content of the diet and tumor incidence. The study's authors suggest linoleic acid increases tumor incidence via its role as a prostaglandin precursor.

Of course, these studies were all performed in rats given a carcinogen. The practical application of these studies is thus a bit limited, but this study is an interesting one. In a controlled clinical trial involving 846 men in which vegetables oils were substituted for saturated fats in the diet, cancer increased notably in the vegetable oil group.

There's a lot to diet and cancer (and is what got me into studying nutrition), but I think one important component that deserves attention is avoidance of linoleic acid.

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on June 04, 2012
at 01:34 AM

Very Nice Mscott!

A2c38be4c54c91a15071f82f14cac0b3

(12682)

on June 04, 2012
at 09:15 PM

Nice, thanks Jay. A lot of variables were at play in the Lyon study in addition to lower linoleic acid intake of course, but it certainly doesn't refute the theory.

4781cf8ae1bfcb558dfb056af17bea94

(4359)

on June 04, 2012
at 08:19 PM

And don't forget the Lyon Diet Heart Study. The cancer endpoint write up is here: http://archinte.jamanetwork.com/article.aspx?volume=158&issue=11&page=1181

6
94480caec9fbbaacc386d86a45efa720

(1007)

on June 03, 2012
at 01:50 PM

A diet high in plant flavonoids, low in sugar, low in PUFAs, with good O3 and CLA input and hormone-free meats seems to be what is recommended to me as best practices. I just had a breast cancer tumor removed a few weeks ago. While I run into a few patients and books that push a vegetarian diet, even some of those concede that meat is not as big of a problem as the hormones and lack of CLA in most available meats.

F5a0ddffcf9ef5beca864050f090a790

(15515)

on June 03, 2012
at 02:55 PM

What is CLA? 03 is omega 3, right?

782d92f4127823bdfb2ddfcbcf961d0e

(5231)

on June 03, 2012
at 04:09 PM

CLA = conjugated linoleic acid, found in grass-fed butter and meats.

3
B0fe7b5a9a197cd293978150cbd9055f

(8938)

on June 03, 2012
at 10:40 AM

Avoidance of PUFA is likely the most important thing of all, see this study. Things like cascara, aspirin, ... can help.

F5a0ddffcf9ef5beca864050f090a790

(15515)

on June 03, 2012
at 02:54 PM

So PUFAs are nuts and oils, right?

276a5e631b62f8e0793987c0496364bb

(1644)

on June 03, 2012
at 03:55 PM

Vegetable/seed oils, yes. Pork is pretty omega-6-y, too.

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on June 03, 2012
at 04:00 PM

PUFAs are huge. Avoid Vegetable oil for sure. I would eat wild salmon twice a week as my exception though. I could be wrong on that. But I would do it personally.

3
77877f762c40637911396daa19b53094

(78467)

on June 03, 2012
at 09:56 AM

One of my brothers had cancer a few years ago. He had radiotherapy. He was told to eat lots of sugary things to help keep his strength and weight up. I couldn't get to grips with the idea of eating lots of sugar and told him so but that's what they told him to do and he's still alive. He was a fish eating vegetarian (probably still is) but apart from a lack of meat, I think his meals have always been old style British home cooking. Not "paleo" but it's much better food than a lot of people eat.

F5a0ddffcf9ef5beca864050f090a790

(15515)

on June 03, 2012
at 10:19 AM

I am going to get some sugar today. My mom is a cancer survivor and she eats everything - gluten, meat, smoked things, sweets.

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on June 04, 2012
at 04:43 AM

In the situation I would need eat sugar of any kind or starches. I might eat raspberries and blueberries on ocassion. That would be it.

956bcad1d462d433a4e1e22f6e3355d5

(1191)

on June 03, 2012
at 10:50 AM

Guess he's being ironic

510bdda8988ed0d4b0ec0b738b4edb73

(20898)

on June 03, 2012
at 03:18 PM

My doctors told me that too. I'm really mad they did. They think that calories matter more than anything else. But cancer feeds on sugar and a keto diet is much more effective than eating sugar and feeding the cancer at the same time as trying to kill it.

F5a0ddffcf9ef5beca864050f090a790

(15515)

on June 03, 2012
at 02:53 PM

@ Korion - I don't know what to do. Sugar or not? Can you guys agree and tell me what you think? By the way, if I eat ice-cream with sugar, does it count as sugar?

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on June 03, 2012
at 03:58 PM

I would say no sugar, dairy, vegetable oil, soy.

Bf57bcbdc19d4f1728599053acd020ab

(5043)

on June 03, 2012
at 12:27 PM

cancer feeds off sugar. Not a good idea. There's a lot of evidence out there with regards to this, if you dig a little.

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on June 03, 2012
at 04:23 PM

I would say no vegetable oil, soy (or other estrogenic substances), but would never say no sugar or dairy, especially if the sugar comes from fruit. Cancer does feed on sugar, but that doesn't make sugar evil (since cancer feeds on protein too). It's like saying starch is a slow sugar because it has to be broken down to glucose first.

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on June 03, 2012
at 10:35 AM

Lol, VB, didn't you said Ray Peat makes no sense? Suddenly buying sugar?

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on June 04, 2012
at 04:44 AM

In the situation I would not eat sugar of any kind or starches. I might eat raspberries and blueberries on ocassion. That would be it.

0
C017efc15dde9ed725a6a245f01e4b88

on December 11, 2014
at 10:38 PM

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