I have a friend with strange blood glucose readings. My friend is eating Paleo (or better say Primal) for a long time. She is eating a moderate carb Primal version. She is doing a lot of endurance sport. Daily cycling/jogging/yoga. On holidays she is speed cycling the mountains and that kind of heavy stuff. She is very thin and muscular. She has never been overweight or a couch potato and was always eating "healthy" (she ate grains in the past but never processed/sugary crap).
All this doesn't sound like diabetes candidate to me. Anyhow she has a quite high fasting blood glucose of 100-120mg/dl. Her HbA1c is 6.6%. But her C-peptide is at the low range of normal (0.79mcg/l).
Whatever she is doing her blood glucose does not go under 100mg/dl. But her blood glucose does not spike up after carb meals either. The blood glucose raises after carbs 10-20mg/dl and is back to "normal" at the 2 hours mark. Exercise does not lower her blood glucose level.
Her diabetes doctor is overstrained...of course! The doctor gave her Metformin which did nothing despite of digestive problems.
For me this doesn't look like diabetes or insulin resistance. But it doesn't look healthy either. Does anyone have related articles/studies or ideas?
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on May 30, 2014
at 06:37 AM
This article talks about how insulin resistance is on the rise in young, slender women who do not even remotely fit the diabetes stereotype. http://www.womenshealthmag.com/health/type-2-diabe...
Metformin sucks! The gastrointestinal problems don't always go away, and I found that starchy meals including bread and rice were the only thing that combatted the intense nausea when I was on it. I finally stopped when I almost crashed my car due to crazy fatigue and a headache that was so bad my eyes wouldn't focus. My recommendation - find another way.
One thing for her to keep in mind - she hasn't necessarily done anything wrong to cause this. The first thing a lot of ladies do after a diabetes or pre-diabetes diagnosis is blame themselves and try to figure out what they should have done differently. Unfortunately, we live in a world where even if you do everything "the right way," there are so many hidden contributors that it can't always be prevented. Luckily for her, she already lives a super-healthy lifestyle, and she's already got a diet and exercise regime that's healthier than what a doctor would tell a diabetic person to implement. She sounds like a fantastic lady with a lot of drive - if she just keeps doing what she's doing, she'll stay pretty healthy.
on May 26, 2014
at 11:14 PM
That HbA1c alone is diagnostic for it. "Thin" makes one think of Type 1 diabetes, or at least some amount of T1D is a factor.
on May 26, 2014
at 07:20 PM
Everything @raydawg brings up is "spot on"... Before I read his responses my impression was "your friend is way over training."
How old is she? How long as she been doing this level of effort? Maybe it's finally catching up with her.
on May 26, 2014
at 12:27 PM
That A1C is pretty high, and that fasting blood sugar is indeed very high. She might be pre-diabetic. Of course all that constant chronic cardio doesn't help the situation - if anything it can cause irreversible heart damage.
Remember, skinny doesn't necessarily mean healthy. At least in obese diabetics, they have the ability to dispose of glucose to fat cells, your friend can only burn them off, but obviously, her fasting blood sugar is high, so this is likely not happening, which is a dangerous situation in the long term. It can cause all sorts of damage to nerve and blood vessels tissues, including eyes, and even kidneys once it gets high enough.
Someone in this situation should be eating a very low carb diet, and no grains.