I recently have been looking into chronic stress and how it relates to chronic disease. C reactive protein seems To be the accepted scientific marker for measuring chronic stress and I ran across this article talking about different Macro ratio diets and their effect on C Reactive Protein. It seemed to find that high fat diets increased crp while high carb diets lowered crp. I know there's some Ray Peat followers here and I know that peat seems to think sugar is fine? But I digress.
If high carb low fat diets are more protective against crp(chronic stress) than high fat low carb diets than does this mean that high carb diets are healthier and should be followed? Why or why not?
asked byVegan4Life_1 (142)
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on April 30, 2013
at 04:37 PM
Comparison of isocaloric very low carbohydrate/high saturated fat and high carbohydrate/low saturated fat diets on body composition and cardiovascular risk: http://www.nutritionandmetabolism.com/content/3/1/7
Inflammatory markers: Five subjects had C reactive protein (CRP) >15 mg/L at baseline or at the completion of the study and were excluded from the analysis. All diets resulted in a significant decrease in CRP with weight loss, independently of diet (p = 0.037).
Conclusion: Under isocaloric conditions VLCARB results in similar fat loss to other conventional dietary patterns although the greater percent weight loss is suggestive of a metabolic advantage. VLCARB resulted in equal improvements in most cardiovascular risk factors compared to conventional weight loss diets while the triacylglycerol reduction offset the LDL cholesterol rise. The more favorable effects of VLCARB on fasting and post prandial plasma insulin concentrations is a significant observation which indicates that this dietary pattern may be a useful strategy for the short-term management of subjects with insulin resistance and hypertriacylglycerolemia.
on April 30, 2013
at 04:19 PM
You probably need a better reference article than from Pritikin, which is a biased, misleading origanization. They mention Atkins dieters CRP was raised by 25%, without mentioning initial and end results; they also mention high carb/low fat lowered CRP ... without mentioning that it was a diet fed to people who were exercising which lowers CRP.
CRP is produced as a means to combat inflammation. So high levels signal inflammation being worked on, while low levels likely mean that there is little inflammation. CRP is not a cause of CVD.
So, it's not that Pritikin is always going to be wrong, but they are always going to be biased - indeed, a lower fat, higher carb diet may work fantastically for some - but any diet that helps one to lower body mass and support an active lifestyle will help lower CRP.
There are different ways to combat inflammation, and in that pursuit it's unlikely that all inflammation anyone suffers from can be treated the same way.