2 Months ago, I posted a question I'm still hacking on about finding optimum lipid profile for heart/brain health in APOE4 here... http://paleohacks.com/questions/80505/potential-hacks-resolve-heart-brain-dilemma-for-apoe4#axzz1klJhxOz9
I've been doing VAP test at 30 day intervals since this first test. Managed to push up size profile from 25% to 40% 'large and fluffy' LDL in the first month - a good early sign. Then per suggestions elsewhere on PH set out to raise HDL (which was flat at 47) in the second by adding coconut oil (2 tbsp/day), add 5000 IU D3 (for total of 8000 IU), and more fermented food (have come to love sauerkraut). Unfortunately, really no effect after another 30 days (HDL from 47 to 48). Maybe it takes time, but I'm thinking something's still not right as LDL went up from 170 to 200 and size went down a bit (only 35% large and fluffy).
Per hints @Quilt and @Grace elsewhere in cyberspace about ultra-sensitivity of APOE4's to dairy, I'm going to remove all dairy this month (I still use lots of butter and occasional cheese).
Any other hack suggestions to add to the mix? Also, happy to take suggestions for look for other clues (e.g. hormones, vitamins, minerals)?
asked byRuss_1 (425)
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on January 28, 2012
at 03:57 PM
Are you doing any high intensity exercising? That seems to make a huge difference in my HDL. Sprints, sprints and more sprints.
on July 07, 2013
at 02:27 AM
I'm 4/4 and at last testing had an HDL of 85; lots of EVOO and avocados :-)
on September 03, 2012
at 02:22 PM
I thought it might be useful to see some HDL history from an APOE4/3. I don't have any VAP data, but it seems low trigs provide similar info. I have to admit I'm trying to make sense of it all myself.
My best lab numbers so far seem to be at a time when I was eating a CW healthy diet (low fat) with high intensity, shorter duration exercise most days. CRP<0.5. My best guess for the change from mid-60s is diet refinement to less processed foods/wheat.
08/30/12: TC 398, LDL 301, HDL 81, trig 79 (PHD removed multi/selenium supp, tallow for cream)
04/27/12: TC 407, LDL 315, HDL 76, trig 79, TSH 1.76, fT3 2.53 (PHD 1-year; 30% C, 20% P, 50% F)
02/23/11: TC 226, LDL 142, HDL 78, trig 32 (45-50% C, 30-35% P, 20-25% F; oats, brown rice, lean meat)
02/27/07: TC 226, LDL 149, HDL 65, trig 61 (CW healthy diet)
As you've questioned, is better to have good looking lab lipids, or maybe instead reduced inflammation/oxidation?
Do you have any updates?