4

votes

Got Some lab results back - Any suggestions? [Updated 5/10/11] Added VAP, Doc Worried

Answered on August 19, 2014
Created February 02, 2011 at 12:30 AM

Hey all -

I recently got some labs done. In April 2010 my Cholesterol was

Total 226 - HDL 103, LDL 117

Just this past week, my results came back

Total 273 - HDL 99, LDL 174

Any cause for concern there?

I am 28yrs old, Male, very athletic. Lacto-Paleo, although this last 10 days have been dairy free as part of an elimination test. Generally between VLC and LC. Energy for the most part is high, occasional low energy days here and there. Supplement with occasional Vit D, occasional fish oil, Vit K, Potassium, Magnesium. I eat a lot of tinned Sardines. All my Meats are Pastured. Most dairy that is consumed is raw, pastured. When I do eat veggies, its spinach, kale, chard, onions, garlic, pickles, jicama, sauerkraut. Sometimes I re-feed with a russet or sweet potato after an intense workout but not always.

Not sure if this is relevant, but I had an elevated liver enzyme (doesn't specify which) and my Compliment level C3 was and has been low. I also had a high titer for Lupus / rheumatoid but has since gone down. In the past year, I have had a low white blood cell count, low red, and enlarged red. Been to Oncology, Rheumatoligy (sp?) and they cannot pinpoint anything.

Thoughts, suggestions? Im not too good on the scientific part of this whole thing yet, so just looking for any info.

EDIT - I'm not sure about the Triglycerides. I will get that tested. What should I be looking for regarding that? Also, What exactly is the VAP test? and what does it show?

EDIT #2 - Ok so I was able to secure complete test results. Also, for reference I got my lab results from Pre-Paleo days.


Jan 2010 - Pre Paleo, Complete SAD offender.

  • Cholesterol - Not taken ?
  • Urea Nitrogen (Bun) - 26
  • Glucose - 84
  • Creatine - 1.20
  • Sodium - 138
  • Potassium - 4.1
  • Calcium - 10.0
  • Protein, Total 7.3
  • TSH - 2.24

April 2010 - about one month in - More Primal / Sisson emphasis

  • Cholesterol, Total - 226
  • HDL - 103
  • Triglycerides - 32
  • LDL - 117
  • Chol/HDLC Ratio - 2.2

Sept 2010 - More Panu / Hyperlipid emphasis

  • Urea Nitrogen (Bun) - 21
  • Glucose - 92
  • Creatine - 1.09
  • Sodium - 136
  • Potassium - 4.8
  • Calcium - 10.1
  • Protein, Total 7.0
  • TSH - 1.25
  • B12 - 551

Jan 2011 - More Panu / Hyperlipid emphasis

  • Cholesterol, Total - 279
  • HDL - 99
  • Triglycerides - 32
  • LDL - 174
  • Chol/HDLC Ratio - 2.8
  • Urea Nitrogen (Bun) - 29
  • Glucose - 88
  • Creatine - 1.22
  • Sodium - 137
  • Potassium - 4.4
  • Calcium - 9.5
  • Protein, Total 7.0
  • TSH - 2.41

May 2011 -

  • Sum Total Cholesterol - 346
  • Total LDL-C - 242
  • Total HDL-C - 90
  • Total VLDL-C - 14
  • Trigs - 35
  • Total Non-HDL-C - 256
  • Total APOB100 Calc - 151
  • LP(a) - 23
  • IDL-C - 13
  • Real-LDL-C - 206
  • Sum Total LDL-C - 242
  • Real-LDL Size Pattern - A
  • Remnant Lipo - 21
  • HDL-2 - 28
  • HDL-3 - 62
  • VLDL-3 - 8

  • Homocysteine, Cardiovascular - 9.1

  • Vit D, 25OH - 47
  • Magnesium - 2.0
  • Protein, Total - 6.9
  • Albumin - 4.8
  • Globulin - 2.1
  • Albumin/Globulin Ratio - 2.3
  • AST - 25
  • ALT - 19
  • Testosterone, Total - 499
  • Testosterone, Free - 45.9
  • C-Reactive Protein - <0.10
  • Cortisol, Total - 14.4
  • Insulin - <2

I'm not gonna lie, the trend of escalating LDL and decreasing HDL does have me a little concerned. Also, The D seems low as does testosterone, and cortisol seems high (but this is just based on the ranges they give). I don't supplement anything other than FCLO, but only 1/2 tsp per day. I have a hard time putting the pieces together based on labs, so I'm hoping people who do "get it" can let me know if anything stands out.

Food Intake -

I tend to not eat breakfast, unless hungry. If I eat breakfast it is eggs, cooked in Pasture butter, Ghee, or Coconut oil, in that order. All my meat I order from a farm, all 100% Pastured. Most meat is ground beef. I try to mix in as much lamb as I can, when available. 1 lb Bacon a week (Pastured), 1/4 lb beef liver every 2-3 days. On Workout Days I have leaner meat, either Mahi Mahi or Ahi. I eat about 2-3 cans of sardines a week. As an appetizer before dinner, I always make a couple "sushi rolls" out of Nori stirps with whatever Im cooking for Iodine. 1-2 times a week I eat smoked oysters. Lindt's Dark chocolate 90% almost daily, about 4 squares. On any days I play soccer or workout I have a large russet or Purple Sweet Potato. In the past 3 weeks, I have been adding another one to test how much I can eat without adding body fat. Fruit is maybe once every 2 weeks and it consists of a handful of berries from the local farmers market.

Thanks a bunch

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 28, 2011
at 11:29 PM

Check out Dr. Davis's take on ApoE4. It's an invitation to do Cordain's Paleo, marry it to the Jaminets' PHD with safe starches. I don't have a clear answer. But I would not ignore your high Lpa nor your high LDL/TC by saying you're Type A; you're Type A but you have some other risk factors. http://www.trackyourplaque.com/blog/2011/07/the-exception-to-low-carb.html

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 28, 2011
at 11:23 PM

ApoEE, means you belong to the 25% whose LDL increases on a high SaFA diet. Can confirm w/genetic testing. I suspect most people wondering why their LDL (and by extension their TC) skyrockets are ApoEEs. Solution: not clear. I would personally do moderate carb Paleo (150g safe starch) and lean meats (avoid too much SaFA). There;re anecdotal accounts of such people doing well on a vega/vegetarian (i.e., low-fat) diet -- viz., their LDL and TC go down with low fat.

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 28, 2011
at 11:19 PM

Er, if that's from your VAP, then you do know that it's rather high. Out of all components, LPa is potentially the most troublesome to control and dangerous. I would look into reducing that number. Google Lpa in mid-twneties. Relates to your blood viscocity. Look around and see if your family has had CVD deaths. Carefully consider implementing fish oil and other measures to counter that. Statins won't reduce that risk. Neither would exercise.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on October 27, 2011
at 11:02 PM

I did have a VAP, the values are in the May 2011 section

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on October 27, 2011
at 11:01 PM

Also, thank you for the answer and suggestions :)

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on October 27, 2011
at 11:00 PM

What is ApoEE??

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 25, 2011
at 10:45 PM

Actually, falase alarm regarding Lp(a); now I see that u never had your VAP done. Still a bit high but not enough to suggest genetic risk. ApoEE still may be the case.

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 25, 2011
at 09:33 PM

Since your Lpa is high, fish oil could be important. Ah, but you could also be ApoEE.

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 25, 2011
at 09:19 PM

Low WBCs are a classic sign of connective issue autoimmune diseases: they're about 1/3 lower in such people from the mid-nromal.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 12, 2011
at 10:46 PM

Thanks, Travis. I really appreciate you taking the time to answer so thoroughly. Looking into my running labs a little deeper, I think I may have been seriously taxing my system in the early stages of switching to Paleo, in the form of dehydration, malnourishment, and insufficient fuel. I'm wondering if I may have done some kidney harm (see above BUN/Creatinine upward trend), and exhausted my adrenals (high cortisol). Trying to really cover my bases now and get back to optimal... and I'm liking Jaminents view on things more and more. Again, many thanks for all your help.

Medium avatar

(39831)

on May 11, 2011
at 08:39 PM

I think the form of the nutrient is more important than the company. For example, Zn in the form of zinc picolinate is supposed to be the most bioavailble. Magnesium glycinate and calcium citrate are what I use. For C, I take this: http://www.thesynergycompany.com/pure_radiance.html plus however many red peppers I choose to eat. I do 2000IU of d3 twice on non-sun days. 200mcg of K-2 in mk-4 if you can find it, but mk-7 is fine. With your oyster and liver intake, you probably don't need Se. I wouldn't do both on the same day. Take Zn in a calcium-free meal on a non-liver day.

Medium avatar

(39831)

on May 11, 2011
at 08:36 PM

CNS, RBCs etc are torching 130g or so of glucose a day no matter what. Eating that amount is risk-free. The more you space out your carb in take the better though. You can still overload the system if you eat a ton of it at once. Eat a 300g tuber with every meal + rice on days when you workout.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 11, 2011
at 07:34 PM

forgot, Vit D...

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 11, 2011
at 07:32 PM

Oops. I had 16oz at around 100g of carbs (based on a couple nutrition calculators) It seems need to up that a bit. I want to add rice as well, but not sure what kind or how to best prepare. Are you of the opinion that, for a active person with a normal metabolism, it matters how many carbs per meal, with respect to blood sugar? Lastly, I remember you take a few supplements, C, Zinc, Selenium? What brands have you found to be preferrential? Ideally little to no fillers, etc? I find it difficult to find quality ones, which is why I have been avoiding.

Medium avatar

(39831)

on May 11, 2011
at 06:45 PM

I'd say that's definitely enough dairy fat to produce the results on your lipid profile. Additionally, I'd say you are undershooting quite a bit on carbs. 16oz of sweet potato is something like 68 grams of carbs. You should be eating double that on a rest day and 3-4x that on a workout day.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 11, 2011
at 06:22 PM

I would eat a large amount of raw, cultured butter - about 1/3 lb, and raw cream - 4-6 oz, at night to up my calories. Often mixed together as a "dessert" with cinnamon. I'd do this 3-4 times a week. Carbs in the form of sweet potato or russet, about 12oz on non rest days, but now I'm closer to 16oz. On rest days, I just upped my veggie intake a tad, but not much. My veggie intake consists garlic, onion, shitake mushrooms, diced and cooked with my meat of choice. Once in a while couple small carrots, or cucumber.

9a5e2da94ad63ea3186dfa494e16a8d1

(15833)

on May 11, 2011
at 06:05 PM

My $0.02, adding vitamin D supplements had pretty significant affects on my health. Better and more consistent mood, reduced muscle and joint pain, better digestion. I think the typical North American / European office worker is woefully deficient in vitamin D.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 11, 2011
at 05:57 PM

Added the food edit above, for your reference. Thanks for the help, Travis.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 11, 2011
at 05:42 PM

One of my goals was/is to test as much as I could, and keep a running log. I know there are myriad variables, but the more info we can all sift through, the better.

667f6c030b0245d71d8ef50c72b097dc

(15976)

on May 11, 2011
at 05:04 PM

Hmmm, really glad you posted the edit. Yours is definitely one of the better, more complete pre-to-post comparisons I've seen. I'm stymied by the movements in what you say, too. Interested to see what more doctor-oriented folks have to say.

A2fe5bbd09c7804fd321e9e9a9f9d199

(1614)

on February 15, 2011
at 09:01 PM

Travis - you eat your natto straight up or mixed in with something else? When at a sushi bar I get it mixed with some tuna chunks, shredded radish and quail egg. But I haven't picked it up to eat at home yet since I'm not sure how to make a quick snack out of it without using rice.

Medium avatar

(39831)

on February 02, 2011
at 07:22 PM

Fish oil supplementation is unnecessary if you're getting your fat from good non-omega6 sources. All of my fat is coming from clarified butter and grass fed lamb with some occasional fish thrown in, so I don't take any fish oil at all. Vitamin D is crucial, but make sure you're getting enough vitamin A and K2 to prevent calcium issues. I eat so much butter that I'm certain I get tons of mk-4 K2, but I eat 50g of natto every day for the 500mcg of mk-7 k2 and take about 150mcg of mk-7 k2. K2 has a remarkably low toxicity, so it's much better to overshoot than undershoot.

100fd85230060e754fc13394eee6d6f1

(18696)

on February 02, 2011
at 03:08 PM

Moreover, low triclycerides and high HDL predicts good particle size.

100fd85230060e754fc13394eee6d6f1

(18696)

on February 02, 2011
at 03:07 PM

Since the triclycerides/HDL ratio is a good indicator of particle size, I wouldn't necessarily worry about getting a VAP. As long as trigs are low, there isn't anything to be concerned about.

100fd85230060e754fc13394eee6d6f1

(18696)

on February 02, 2011
at 02:59 PM

What in this profile makes you think he might "have something"? His HDL is high, and the only remaining question is trigs, which if they are low means an excellent profile.

691f120a3e7a1a036845d105d86c99a3

(3641)

on February 02, 2011
at 01:15 PM

i probably should have read your's first Travis. You and I think alike and you say things more to the point.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on February 02, 2011
at 07:30 AM

Been Lacto-Paleo almost a year. Before that it was as SAD as you could get

77ecc37f89dbe8f783179323916bd8e6

(5002)

on February 02, 2011
at 02:13 AM

How long have you been lactopaleo? What was your diet like two years ago?

E3267155f6962f293583fc6a0b98793e

(1085)

on February 02, 2011
at 01:43 AM

What Travis said.

5672b2d190891342389e764cc4056ca9

(1304)

on February 02, 2011
at 01:30 AM

Thanks Kirik. @Todd: first test in 2008, second in 2010.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on February 02, 2011
at 01:22 AM

How long did it take for that number to jump?

5edbf85deaf83e13b176df023abb154d

(1293)

on February 02, 2011
at 01:14 AM

Look up Dr. Harris' PaNu blog. He's not exactly head-over-heels about fish oil supplementation. Just an fyi.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on February 02, 2011
at 01:09 AM

I will look once I get the documentation. I had the results read to me over the phone.

5edbf85deaf83e13b176df023abb154d

(1293)

on February 02, 2011
at 12:57 AM

I'm almost certain that you should have gotten triglycerides done alongside the testing you got done. You might call and make sure that there aren't also triglyceride numbers in there for you.

5edbf85deaf83e13b176df023abb154d

(1293)

on February 02, 2011
at 12:49 AM

Agreed. At the same time, there is a trend of rising LDL with the information given, so in the absence of more information I don't want to tell Todd to just totally blow it off. No reason for concern, of course, but more evidence/follow up might be called for, imo.

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12 Answers

6
Medium avatar

on February 02, 2011
at 12:44 AM

What about triglycerides? With your exceptional HDL and presumably low TGs, you have a strong inverse correlation with mortality. If you're concerned about your LDL, get a VAP test and you'll almost certainly have mostly large, buoyant LDL predominating.

E3267155f6962f293583fc6a0b98793e

(1085)

on February 02, 2011
at 01:43 AM

What Travis said.

691f120a3e7a1a036845d105d86c99a3

(3641)

on February 02, 2011
at 01:15 PM

i probably should have read your's first Travis. You and I think alike and you say things more to the point.

3
Medium avatar

on May 11, 2011
at 05:16 PM

I wouldn't be alarmed in the least bit. My doctor is an idiot as well. I decreased TC by 17%, TGs by 31%, LDL by 23% and increased HDL by 22% in two months and she still wants to put me on medication. I don't even return her calls. Our medical establishment is a bad joke, my friend. I'm not sure if these doctors even take a nutrition class in school. I bet they take plenty of "how to capitalize on pharmaceutical dispensing" courses though. LDL taken out of context is probably the poorest indicator of health of anything on the panel.

Post a typical day's worth of food between your last two cholesterol tests.

My guess is that your myristic/palmitic acid intake is still fairly high. Try shifting your fat intake to ruminant tallow.

To address the catabolism/cortisol issue, I would increase carbohydrates to 150g per day minimum. That would then likely increase testosterone assuming you don't have a marginal Zn, Cu or Se status and that you continue to eat a fair amount of quality saturated fat.

Edit: So how much butter did you eat per day in the last few months? When you eat a potato or sweet potato do you put tons of butter in it like I did? How many grams of carbs per day would you say? If you didn't really eat that much butter or coconut oil, I'd say that it might be a lack of starch as Jaminet was suggesting. Maybe that's what caused the big change for me.

To be clear, I'm not certain in the least bit that really high LDL matters, but assuming that you'd like to play it safe and have it around 200-something, you could just eat a tuber with every meal like I do and cut out all butter and see how it goes. I would estimate that I'll be back within that range in 3-6 months.

As a whole, your diet looks excellent and will produce far better overall health and longevity than anything your doctor would have you eat, if they even mentioned diet. Shouldn't have to worry about missing out on any micros.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 11, 2011
at 05:57 PM

Added the food edit above, for your reference. Thanks for the help, Travis.

Medium avatar

(39831)

on May 11, 2011
at 08:36 PM

CNS, RBCs etc are torching 130g or so of glucose a day no matter what. Eating that amount is risk-free. The more you space out your carb in take the better though. You can still overload the system if you eat a ton of it at once. Eat a 300g tuber with every meal + rice on days when you workout.

Medium avatar

(39831)

on May 11, 2011
at 08:39 PM

I think the form of the nutrient is more important than the company. For example, Zn in the form of zinc picolinate is supposed to be the most bioavailble. Magnesium glycinate and calcium citrate are what I use. For C, I take this: http://www.thesynergycompany.com/pure_radiance.html plus however many red peppers I choose to eat. I do 2000IU of d3 twice on non-sun days. 200mcg of K-2 in mk-4 if you can find it, but mk-7 is fine. With your oyster and liver intake, you probably don't need Se. I wouldn't do both on the same day. Take Zn in a calcium-free meal on a non-liver day.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 11, 2011
at 06:22 PM

I would eat a large amount of raw, cultured butter - about 1/3 lb, and raw cream - 4-6 oz, at night to up my calories. Often mixed together as a "dessert" with cinnamon. I'd do this 3-4 times a week. Carbs in the form of sweet potato or russet, about 12oz on non rest days, but now I'm closer to 16oz. On rest days, I just upped my veggie intake a tad, but not much. My veggie intake consists garlic, onion, shitake mushrooms, diced and cooked with my meat of choice. Once in a while couple small carrots, or cucumber.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 11, 2011
at 07:32 PM

Oops. I had 16oz at around 100g of carbs (based on a couple nutrition calculators) It seems need to up that a bit. I want to add rice as well, but not sure what kind or how to best prepare. Are you of the opinion that, for a active person with a normal metabolism, it matters how many carbs per meal, with respect to blood sugar? Lastly, I remember you take a few supplements, C, Zinc, Selenium? What brands have you found to be preferrential? Ideally little to no fillers, etc? I find it difficult to find quality ones, which is why I have been avoiding.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 11, 2011
at 07:34 PM

forgot, Vit D...

Medium avatar

(39831)

on May 11, 2011
at 06:45 PM

I'd say that's definitely enough dairy fat to produce the results on your lipid profile. Additionally, I'd say you are undershooting quite a bit on carbs. 16oz of sweet potato is something like 68 grams of carbs. You should be eating double that on a rest day and 3-4x that on a workout day.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on May 12, 2011
at 10:46 PM

Thanks, Travis. I really appreciate you taking the time to answer so thoroughly. Looking into my running labs a little deeper, I think I may have been seriously taxing my system in the early stages of switching to Paleo, in the form of dehydration, malnourishment, and insufficient fuel. I'm wondering if I may have done some kidney harm (see above BUN/Creatinine upward trend), and exhausted my adrenals (high cortisol). Trying to really cover my bases now and get back to optimal... and I'm liking Jaminents view on things more and more. Again, many thanks for all your help.

3
691f120a3e7a1a036845d105d86c99a3

(3641)

on February 02, 2011
at 01:13 PM

I don't think any of this is really a concern until you get more info.

In addition to triglycerides which are the most useful, you might want to get a look at LDL particle size. Paleo--and meat eating in general--can increase LDL. But in absence of massice amounts of carbohydrate all the LDL will be a big fluffy type which is similar to HDL in terms of being good for you.

If you have low Triglycerides and get a LDL size breakdown and you have very few 'small' LDL, you are probably in great shape.

The science of cholesterol has changed so much that HDL,LDL and total are somewhat useless numbers at this point for determining health.

100fd85230060e754fc13394eee6d6f1

(18696)

on February 02, 2011
at 03:08 PM

Moreover, low triclycerides and high HDL predicts good particle size.

3
209d2fc1f43df88348031c7c38077172

(693)

on February 02, 2011
at 12:43 AM

What do your triglycerides look like? I think they are a better indicator of problems than just HDL/LDL.

5edbf85deaf83e13b176df023abb154d

(1293)

on February 02, 2011
at 12:49 AM

Agreed. At the same time, there is a trend of rising LDL with the information given, so in the absence of more information I don't want to tell Todd to just totally blow it off. No reason for concern, of course, but more evidence/follow up might be called for, imo.

2
5edbf85deaf83e13b176df023abb154d

on February 02, 2011
at 12:39 AM

Any cause for concern?

Let's not elevate it to CONCERN, but let's be real here: you might have something that, as you get older, bears watching. Continue to seek and don't panic by any means. You're 28, which means that you're at a ridiculously low risk for any cardiac issue.

Keep looking and seeking. You have shown that you're not afraid to tinker and test with your diet, so keep doing that.

Best wishes.

100fd85230060e754fc13394eee6d6f1

(18696)

on February 02, 2011
at 02:59 PM

What in this profile makes you think he might "have something"? His HDL is high, and the only remaining question is trigs, which if they are low means an excellent profile.

1
3c6b4eed18dc57f746755b698426e7c8

on October 25, 2011
at 09:12 PM

Hate to make this belated observation but your Lp(a) is high. It's a genetic factor that cannot be addressed by diet or medication, unfortunately. But you should still do something about it. Google Dr. Sinatra and see if his steps for lowering LP(a) makes sense. People claim to have lowered Lp(a) using his method. You should lower that to under 8, if possible. Do you have a family history of CVD on either side of the family tree? Your rise in TC also could be that you're ApoEE.

Now the other possible issue is your kidneys. Your BUN and Creatinine are high for a 28 year old guy. I dont think that's because you're overding protein; you seem to be eating enough carbs. Were u tested for Lupus, Lupus Nephritis? Did your rheumy check for ANA and antibody tests for various connective tissue related diseases? If you're positive for RA, then it's best to avoid dairy, even raw dairy, and all nighshades.

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 25, 2011
at 10:45 PM

Actually, falase alarm regarding Lp(a); now I see that u never had your VAP done. Still a bit high but not enough to suggest genetic risk. ApoEE still may be the case.

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 25, 2011
at 09:19 PM

Low WBCs are a classic sign of connective issue autoimmune diseases: they're about 1/3 lower in such people from the mid-nromal.

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 25, 2011
at 09:33 PM

Since your Lpa is high, fish oil could be important. Ah, but you could also be ApoEE.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on October 27, 2011
at 11:00 PM

What is ApoEE??

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on October 27, 2011
at 11:02 PM

I did have a VAP, the values are in the May 2011 section

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on October 27, 2011
at 11:01 PM

Also, thank you for the answer and suggestions :)

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 28, 2011
at 11:29 PM

Check out Dr. Davis's take on ApoE4. It's an invitation to do Cordain's Paleo, marry it to the Jaminets' PHD with safe starches. I don't have a clear answer. But I would not ignore your high Lpa nor your high LDL/TC by saying you're Type A; you're Type A but you have some other risk factors. http://www.trackyourplaque.com/blog/2011/07/the-exception-to-low-carb.html

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 28, 2011
at 11:19 PM

Er, if that's from your VAP, then you do know that it's rather high. Out of all components, LPa is potentially the most troublesome to control and dangerous. I would look into reducing that number. Google Lpa in mid-twneties. Relates to your blood viscocity. Look around and see if your family has had CVD deaths. Carefully consider implementing fish oil and other measures to counter that. Statins won't reduce that risk. Neither would exercise.

3c6b4eed18dc57f746755b698426e7c8

(5147)

on October 28, 2011
at 11:23 PM

ApoEE, means you belong to the 25% whose LDL increases on a high SaFA diet. Can confirm w/genetic testing. I suspect most people wondering why their LDL (and by extension their TC) skyrockets are ApoEEs. Solution: not clear. I would personally do moderate carb Paleo (150g safe starch) and lean meats (avoid too much SaFA). There;re anecdotal accounts of such people doing well on a vega/vegetarian (i.e., low-fat) diet -- viz., their LDL and TC go down with low fat.

1
62ed65f3596aa2f62fa1d58a0c09f8c3

(20807)

on February 02, 2011
at 04:40 AM

I'd keep a cautious watch and see how things proceed. SOme doctors have noted initial higher cholesterol readings after beginning paleo, but then those numbers later go back down. Also, there can be quite a bit of natural variation in cholesterol readings between one day and the next and also quite a bit of variation between lab testings. I too am still not sold on fish oil pill supplements, but occasional modest use probably is not a big deal either way.

THis one is tricky. There have been other weird symptoms and by the description of the situation, I am not sure if they were present before paleo or only came to pass after paleo. So it's hard for me to say much in that regard. However, if triglycerides are not high, and/or if there is correlation in the timing of the probs with paleo, one option might be to try a bit more healthy carb, especially if the person is not overweight and/or is a heavy exerciser. Paleo is often lower carb than SAD but it is not a requirement for it to be very low carb. SOme paleo eaters find that regular consumption of healthy starches and a moderate amount of fruit help them feel at their best.

1
5672b2d190891342389e764cc4056ca9

(1304)

on February 02, 2011
at 01:12 AM

I'm getting very suspicious of supplementation with fish oil and Vit D. I know this runs counter to what the big names in the paleo community say, but my LDL cholesterol jumped from 114 to 240, and the major changes were 5:

  • High fat
  • Low carb
  • Vit D supplementation
  • Fish oil supplementation
  • Age

Of course there might be other reasons for the rise in my LDL cholesterol, but I decided to stop taking fish oil supplements (and get O3 from real fish), to ditch the Vit D, and to take another test soon.

5edbf85deaf83e13b176df023abb154d

(1293)

on February 02, 2011
at 01:14 AM

Look up Dr. Harris' PaNu blog. He's not exactly head-over-heels about fish oil supplementation. Just an fyi.

5672b2d190891342389e764cc4056ca9

(1304)

on February 02, 2011
at 01:30 AM

Thanks Kirik. @Todd: first test in 2008, second in 2010.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on February 02, 2011
at 01:22 AM

How long did it take for that number to jump?

Medium avatar

(39831)

on February 02, 2011
at 07:22 PM

Fish oil supplementation is unnecessary if you're getting your fat from good non-omega6 sources. All of my fat is coming from clarified butter and grass fed lamb with some occasional fish thrown in, so I don't take any fish oil at all. Vitamin D is crucial, but make sure you're getting enough vitamin A and K2 to prevent calcium issues. I eat so much butter that I'm certain I get tons of mk-4 K2, but I eat 50g of natto every day for the 500mcg of mk-7 k2 and take about 150mcg of mk-7 k2. K2 has a remarkably low toxicity, so it's much better to overshoot than undershoot.

A2fe5bbd09c7804fd321e9e9a9f9d199

(1614)

on February 15, 2011
at 09:01 PM

Travis - you eat your natto straight up or mixed in with something else? When at a sushi bar I get it mixed with some tuna chunks, shredded radish and quail egg. But I haven't picked it up to eat at home yet since I'm not sure how to make a quick snack out of it without using rice.

9a5e2da94ad63ea3186dfa494e16a8d1

(15833)

on May 11, 2011
at 06:05 PM

My $0.02, adding vitamin D supplements had pretty significant affects on my health. Better and more consistent mood, reduced muscle and joint pain, better digestion. I think the typical North American / European office worker is woefully deficient in vitamin D.

0
C9c01c688258ee48ba8f7ebc0017a14f

on February 19, 2011
at 05:19 PM

Many have asked about the VAP Cholesterol Test and its value in this forum. I encourage you to see patient cases and sample VAP Test lab reports on Dr. Michael Cobble's lipid discussion at http://www.cobblescorner.com. The post "Marathon Man" might be of interest to those with the paleo lifestyle.

0
7c068e0afd33ae34618499578444a5e1

on February 13, 2011
at 11:08 PM

Hey, don't worry at all! Maybe you have a hidden inflammation. Did you check your c-reactive protein? Anyway, check this out: http://www.youtube.com/watch?v=uv2Z3UWYJKk&feature=related

0
4f135301ab317e1b7b75ade9d25a4dad

on February 13, 2011
at 10:03 PM

Cholesterol Is not a parameter that is significantly worth worrying about. Scientific evidence does not support C as the cause of anything to have angst over. It is right there in the 'over blown - hyped' column.

0
5f0158c23fcb5636e57b4ce097784da0

(1386)

on February 02, 2011
at 04:09 PM

blood lipids are pretty much the least important and least interesting thing you can measure in a lab.. these lipids just tell you "something is happening elsewhere". testing of D, Thyroid Status, Liver Status, Kidney Status, Ferritin, CRP, A1c, Uric Acid and Homocysteine for example bear far more diagnostic and predictive power for health. for example, the worsening of your lipid profile could easily just be caused by a slowing down of your thyroid. or, if your homocysteine or 1Ac is high, blood lipids would be pretty much the last thing you should be worried about..

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