3

votes

Is L-Carnosine the key to a paleo diet?

Answered on August 19, 2014
Created September 29, 2011 at 2:50 PM

http://www.ncbi.nlm.nih.gov/pubmed/15955546?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=10

I think it is and I am getting ready to write a series on it.

If you all have not read this article I suggest you consider it.

7d64d3988de1b0e493aacf37843c5596

(2861)

on September 30, 2011
at 02:04 AM

Quilt, but you still have not answered why you believe a Paleo diet is better source of carnosine than other diets that emphasize muscle meat. Some versions of Paleo try to limit protein for longevity and other reasons and focus on fats instead of muscle meat. As I said, SAD normally has a good amount of muscle meat, and even conventional "health conscious" people focus on lean muscle meat, like chicken and turkey breast. By eating "lean" meats, they are actually getting a higher carnosine density. Choline on the other hand is often lacking and may help prevent rampant fatty liver disease.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on September 30, 2011
at 12:22 AM

Cm has never talked about carnosine.....choline is important but ithink carnosine is the key component of why a paleo diet is best for aging and longevity. Choline is not in my top three.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on September 30, 2011
at 12:21 AM

Plus one for doing good stuff.....

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on September 30, 2011
at 12:20 AM

I like paul a lot. We just disagree in spots

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on September 30, 2011
at 12:19 AM

Rob it does help wrinkles. It actually increase our hayslip number. I got sent a great email from a reader named frank and i answered his question about carnosine in the comment section. His email is going to stimulate a series on it.

3c997ffae3db9464325b96979346d9e9

(1290)

on September 29, 2011
at 11:05 PM

The enzyme carnosinase breaks down carnosine into its components. Vegetarians obviously get no benefit from carnosine but to get further benefit than just from diet (should you care to pursue the unnatural) you'll need to ingest enough carnosine to overwhelm the carnosinase.

742ff8ba4ff55e84593ede14ac1c3cab

(3536)

on September 29, 2011
at 09:12 PM

Does reduced glycation mean less wrinkles? Is carnosine heat resistant, or does cooking destroy this vital nutrient?

77877f762c40637911396daa19b53094

(78467)

on September 29, 2011
at 08:28 PM

@Quilt: Choline is essential for brain and fat burn. Jaminet was writing a lot about choline deficiency and inability to burn fat. I know you don't like the dude much but lets look at the evidence.

5e36f73c3f95eb4ea13a009f4936449f

(8280)

on September 29, 2011
at 08:27 PM

Define what you mean by "the key". That article is specific on glycation. I think there are a lot of other benefits to a paleo diet than just reduced glycation.

77877f762c40637911396daa19b53094

(78467)

on September 29, 2011
at 08:27 PM

@Paleo - because all life on Earth makes it except humans and vampire bats who learned to suck it up :P

7d64d3988de1b0e493aacf37843c5596

(2861)

on September 29, 2011
at 07:50 PM

Quilt, it looks like L-carnosine is mainly found in the muscle, so eating high-fat Paleo does not seem to have any particular advantages in terms of l-carnosine over people eating SAD or more "health conscious" people eating lean muscle meats like chicken and turkey breast. In the studies that Chris Masterjohn reviewed, choline almost totally protected the liver from fatty liver disease. Liver and egg yolks have been neglected in many modern diets, especially after the cholesterol scare. I just don't see carnosine being that big of a deal in Paleo unless you are a former vegan.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on September 29, 2011
at 07:22 PM

I dont think choline comes close. I have researched both extensively and the case for carnosine is offmthencharts and goes back pretty far.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on September 29, 2011
at 07:21 PM

Not the supplement mallory.....carnosine is loaded in grass fed meat meat.....specifically animal flesh

7d64d3988de1b0e493aacf37843c5596

(2861)

on September 29, 2011
at 06:58 PM

Majkinetor, why do you think vitamin C is particularly special?

77877f762c40637911396daa19b53094

(78467)

on September 29, 2011
at 06:30 PM

still, there are magic nutrients, like Vitamin C.

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on September 29, 2011
at 04:00 PM

Carnosine is a good thing, but I agree that it's not the lynchpin that holds paleo together. The only folks who don't get adequate levels are vegetarians/vegans and those who restrict animal products excessively (dieters).

Medium avatar

(39821)

on September 29, 2011
at 03:56 PM

Hadn't heard about that; good find.

C471216c9fb4fcf886b7ac84a4046b49

(1371)

on September 29, 2011
at 03:35 PM

there are magic supplements to eating...

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3 Answers

1
3c997ffae3db9464325b96979346d9e9

on September 29, 2011
at 08:20 PM

I've been taking 2 grams a day for years. Regardless of paleo stuff this and r-lipoic acid (from one particular company that employs a non-degrading process) are good anti-aging supplements. Benfotiamine is another inhibitor of glycation. L-Carnosine is expensive but there are newer online bulk suppliers that have brought the price down a lot.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on September 30, 2011
at 12:21 AM

Plus one for doing good stuff.....

1
7d64d3988de1b0e493aacf37843c5596

(2861)

on September 29, 2011
at 03:52 PM

I doubt it. There is too much going on to just point at a single amino-acid or micro-nutrient. Choline looks just as interesting as L-carnosine. If you have a deficiency in any mineral, fixing it will probably have pretty significant effects as well, probably more so than someone switching from SAD to paleo to boost l-carnosine. I am not sure that the SAD would be particularly deficient in l-carnosine.

77877f762c40637911396daa19b53094

(78467)

on September 29, 2011
at 08:27 PM

@Paleo - because all life on Earth makes it except humans and vampire bats who learned to suck it up :P

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on September 29, 2011
at 04:00 PM

Carnosine is a good thing, but I agree that it's not the lynchpin that holds paleo together. The only folks who don't get adequate levels are vegetarians/vegans and those who restrict animal products excessively (dieters).

77877f762c40637911396daa19b53094

(78467)

on September 29, 2011
at 06:30 PM

still, there are magic nutrients, like Vitamin C.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on September 29, 2011
at 07:22 PM

I dont think choline comes close. I have researched both extensively and the case for carnosine is offmthencharts and goes back pretty far.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on September 30, 2011
at 12:20 AM

I like paul a lot. We just disagree in spots

77877f762c40637911396daa19b53094

(78467)

on September 29, 2011
at 08:28 PM

@Quilt: Choline is essential for brain and fat burn. Jaminet was writing a lot about choline deficiency and inability to burn fat. I know you don't like the dude much but lets look at the evidence.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on September 30, 2011
at 12:22 AM

Cm has never talked about carnosine.....choline is important but ithink carnosine is the key component of why a paleo diet is best for aging and longevity. Choline is not in my top three.

7d64d3988de1b0e493aacf37843c5596

(2861)

on September 29, 2011
at 06:58 PM

Majkinetor, why do you think vitamin C is particularly special?

7d64d3988de1b0e493aacf37843c5596

(2861)

on September 29, 2011
at 07:50 PM

Quilt, it looks like L-carnosine is mainly found in the muscle, so eating high-fat Paleo does not seem to have any particular advantages in terms of l-carnosine over people eating SAD or more "health conscious" people eating lean muscle meats like chicken and turkey breast. In the studies that Chris Masterjohn reviewed, choline almost totally protected the liver from fatty liver disease. Liver and egg yolks have been neglected in many modern diets, especially after the cholesterol scare. I just don't see carnosine being that big of a deal in Paleo unless you are a former vegan.

7d64d3988de1b0e493aacf37843c5596

(2861)

on September 30, 2011
at 02:04 AM

Quilt, but you still have not answered why you believe a Paleo diet is better source of carnosine than other diets that emphasize muscle meat. Some versions of Paleo try to limit protein for longevity and other reasons and focus on fats instead of muscle meat. As I said, SAD normally has a good amount of muscle meat, and even conventional "health conscious" people focus on lean muscle meat, like chicken and turkey breast. By eating "lean" meats, they are actually getting a higher carnosine density. Choline on the other hand is often lacking and may help prevent rampant fatty liver disease.

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