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Why does consuming button mushroom and green tea reduce the risk of breast cancer dramatically?

Answered on August 19, 2014
Created August 27, 2012 at 7:51 PM

Here is the study: http://onlinelibrary.wiley.com/doi/10.1002/ijc.24047/full

What wikipedia says: "A 2009 case control study of 2,018 women correlated a large decrease of breast cancer incidence in women who consumed mushrooms. Women in the study who consumed fresh mushrooms daily were 64% less likely to develop breast cancer, while those that combined a mushroom diet with regular green tea consumption reduced their risk of breast cancer by nearly 90%."

Does anybody know whether the this reduction in breast cancer is caused by anti-carcinogenic activity or by reducing estrogen (or other hormonal effects)? While the study suggests anti-carcinogenic causes, they still did not conclude with it as the responsible source of cancer-reduction.

Dd74e6399ae697d8603dc9aa74fbafae

(695)

on August 27, 2012
at 09:44 PM

While the women who consumed the most mushrooms and green tea were younger overall, they also consumed more alcohol, were less physically active and spent very little times in rural areas (living in the stress of chinese urban life). Thus I doubt that your conclusion is the full answer.

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3 Answers

1
A2c38be4c54c91a15071f82f14cac0b3

(12682)

on August 27, 2012
at 08:15 PM

My opinion, I think the fact that green tea and mushrooms have notable aromatase inhibiting (estrogen reducing) effects, this is a big part of why they appear protective against breast cancer. The effect of estrogen of breast cancer has been an increasingly accepted and studied theory since Leonard Cohen (not the awesome singer, but an equally awesome scientist) reduced breast tumors in rats by giving them an anti-estrogen.

Still, I don't think reducing estrogen is the only way these foods reduce breast cancer. I think it's a big (and perhaps the main) reason, but there are a number of other studied possible mechanisms by which these foods can reduce cancer that don't relate to estrogen reduction.

Oh and as an interesting side note, much of the beneficial effects mushrooms seems to have in this regard seems to be due to their conjugated linoleic acid content, which is also found in grass fed dairy and beef fat.

0
6b8d12fc3e43179f9ae1765a4d1a9dc2

(5914)

on August 27, 2012
at 09:39 PM

Without reading the study - because the women that eat mushrooms and drank green had the healthiest diets and exercised more?

Same as nearly every other study.

Dd74e6399ae697d8603dc9aa74fbafae

(695)

on August 27, 2012
at 09:44 PM

While the women who consumed the most mushrooms and green tea were younger overall, they also consumed more alcohol, were less physically active and spent very little times in rural areas (living in the stress of chinese urban life). Thus I doubt that your conclusion is the full answer.

0
782d92f4127823bdfb2ddfcbcf961d0e

on August 27, 2012
at 08:07 PM

My trainer just sent me an article about green tea this last weekend. Apparently, a polyphenol in green tea (EGCG) reactivates estrogen receptors in certain hormone resistant breast cancers. You can read the study here. It's a little dense to read but interesting. BTW, he sent it to me because I'm going through menopause and the hot flashes have been horrible. My bHRT hadn't been working well and he thought maybe there weren't enough estrogen receptors turned on for the HRT to have an effect. Going to get some green tea today and try it out.

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