3

votes

What Do YOU Think Causes Cancer?

Answered on September 12, 2014
Created January 07, 2013 at 5:27 PM

I'm curious as to what people on here think causes cancer. I've heard everything from cell phones to plastic to certain foods.

Ed71ab1c75c6a9bd217a599db0a3e117

(25477)

on January 07, 2013
at 11:05 PM

anything that chronically disrupts cellular signaling to interrupt the p53 gene which is the protector of the genome.

194d8e8140425057fe06202e1e5822a7

(3979)

on January 07, 2013
at 10:02 PM

"GMOs because they alter your DNA" source PLEASE

5bd7f43c7da83282bcb78e3aa33832e0

(266)

on January 07, 2013
at 09:41 PM

This post is brilliant! I hope you stick around!

5bd7f43c7da83282bcb78e3aa33832e0

(266)

on January 07, 2013
at 09:39 PM

So are you suggesting that if I want to eat starch, I should be eating meals that are just e.g. white rice and veggies? A stir-fry perhaps?

A2c38be4c54c91a15071f82f14cac0b3

(12682)

on January 07, 2013
at 08:16 PM

Starch digestion occurs primarily in the SI, not the stomach, so there's no reason why you shouldn't be able digest the two macros from the same meal. There's also some evidence that combining protein and starch attenuates markers of cancer risk compared to protein alone: http://www.ncbi.nlm.nih.gov/pubmed/16410726

D8ac2615b6631ff22d67234adf7b6645

on January 07, 2013
at 07:24 PM

I also agree with this. We can't prevent DNA damage and I think it's the failing/suboptimal immune system that actually allows the tumor to grow unabated.

Cb9a270955e2c277a02c4a4b5dad10b5

(10989)

on January 07, 2013
at 07:23 PM

consumption, cancer rates were the highest. This is in stark contrast to the fact that in populations who did not consume grains, cancer did not exist."

Cb9a270955e2c277a02c4a4b5dad10b5

(10989)

on January 07, 2013
at 07:22 PM

consumption, cancer rates were the highest. This is in stark contrast to the fact that in populations who did not consume grains, cancer did not exist.

Cb9a270955e2c277a02c4a4b5dad10b5

(10989)

on January 07, 2013
at 07:22 PM

Yea, if I had to put my money on it then wheat would be up near the very top. I wish I could find the original paper for what I'm about to show you but all I can find are write-ups on it. "In 1843, a physician named Stanislas Tanchou spoke at the Paris Medical Society Conference. He claimed that he could predict the cancer rates in major European cities over the next 50 years. He based his predictions on the percentage of grains being consumed in each major city. What is astonishing is that, over time, his predictions turned out to be correct. In the cities that had the highest grain

C8a5c6d2804326646bb274e491f7f21b

(534)

on January 07, 2013
at 07:16 PM

and since when is white rice carcinogenic?

77188106a9c27a22ad47d0ef7318de7a

(922)

on January 07, 2013
at 07:01 PM

Blood and starch together is terrible for you; yet it's considered to be essential for any meal to be "complete." The only way to get optimal protein digestion into amino acids in the stomach and thus absorption in the intestines is to eat your meat with vegetables and greens only. Starch and protein don't combine.

F5a0ddffcf9ef5beca864050f090a790

(15515)

on January 07, 2013
at 06:52 PM

Combining blood and starch... what about meat and potatoes? Aros con pollo? Pork lo mein?

F5a0ddffcf9ef5beca864050f090a790

(15515)

on January 07, 2013
at 06:50 PM

What about sugar and processed grains then? I bet they are even more carcinogenic than white rice!

0382fa263de4c83328dc34a56e25437f

(4238)

on January 07, 2013
at 06:43 PM

This is the only answer, honestly. Plants and animals of all kinds develop cases of cellular replication (and sorry, they don't all eat grain, or smoke, or whatever). I don't doubt that unhealthy diets, various radiations and other factors contribute in various ways to any imbalance, cancerous growths included, but the fact remains.

3fc95bca9e723edfbbb72b172798ab49

(1354)

on January 07, 2013
at 06:31 PM

I know this response may SOUND smarmy, but it really is the only proper response. This question is somewhat like asking, "What do YOU think causes bruising?". Well...a lot of things can cause it.

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9 Answers

11
0a21952679d5c9a60a06594cd4871b27

(215)

on January 07, 2013
at 05:51 PM

Uncontrolled cell replication ;)

0382fa263de4c83328dc34a56e25437f

(4238)

on January 07, 2013
at 06:43 PM

This is the only answer, honestly. Plants and animals of all kinds develop cases of cellular replication (and sorry, they don't all eat grain, or smoke, or whatever). I don't doubt that unhealthy diets, various radiations and other factors contribute in various ways to any imbalance, cancerous growths included, but the fact remains.

3fc95bca9e723edfbbb72b172798ab49

(1354)

on January 07, 2013
at 06:31 PM

I know this response may SOUND smarmy, but it really is the only proper response. This question is somewhat like asking, "What do YOU think causes bruising?". Well...a lot of things can cause it.

6
Cb9a270955e2c277a02c4a4b5dad10b5

(10989)

on January 07, 2013
at 06:07 PM

Grains..

The most interesting part of this study was the role grains played in causing cancer.?? Vegans, vegetarians, and most Americans get the majority of their carbs from grains.?? As the researchers pointed out, grain based carbs might be the main problem, not carbs in general.

A high-carb diet is bad for cancer patients, but a grain based diet is even worse.

???Usually, CHO restriction is not only limited to avoiding sugar and other high-GI foods, but also to a reduced intake of grains. Grains can induce inflammation in susceptible individuals due to their content of omega-6 fatty acids, lectins and gluten [159, 160]. In particular gluten might play a key role in the pathogenesis of auto-immune and inflammatory disorders and some malignant diseases.???

There are hundreds of reasons grains contribute to cancer, so this article will cover just a few.

Grains cause inflammation by themselves, regardless of whether or not the diet is low in carbohydrates.?? This occurs through several pathways.

Grains contain omega-6 fats, lectins, phytates, damaging fiber, and gluten.?? Anything that contributes to inflammation will make cancer worse, but gluten has several special characteristics that exacerbate cancer growth.?? Gluten overstimulates the release of zonulin, a protein that regulates the space between epithelial cells in the small intestine.?? This causes dysregulation between cells which promotes cancer growth throughout the digestive tract.

???In the small intestine, gluten triggers the release of zonulin, a protein that regulates the tight junctions between epithelial cells and therefore intestinal, but also blood-brain barrier function. Recent evidence suggests that overstimulation of zonulin in susceptible individuals could dysregulate intercellular communication promoting tumorigenesis at specific organ sites???

Reducing total carbohydrate load was not nearly as important as removing grain based carbohydrates.?? It???s sad to think that Steve Jobs was being told to eat not only a high-carb diet, but also to eat 8-11 servings of ???healthy??? whole grains a day.

The study authors were quick to offer a solution: the paleo diet.?? Both animal and human studies have shown the paleo diet is extremely effective at improving glucose tolerance and decreasing your risk for disease ??? far more so than the grain based Mediterranean diet.?? Switching to a paleo diet would remove grains, and lower the total glycemic index of the person???s diet. ?? Vegetables have a far lower glycemic index than grains. ??Studies have shown this results in better glucose control and less inflammation.

???Paleolithic-type diets, that by definition exclude grain products, have been shown to improve glycemic control and cardiovascular risk factors more effectively than typically recommended low-fat diets rich in whole grains [162]. These diets are not necessarily very low CHO diets, but focus on replacing high-GI modern foods with fruits and vegetables, in this way reducing the total GL.???

Even if the diet was high in carbohydrates, it would be better than a low-carb, grain based diet. But none of them would touch the Bulletproof Diet, which also accounts for another major inflammation (and cancer) contributor: mycotoxins.

Cancer: A Novel (Neolithic) Problem Cancer is a modern disease, and was almost unheard of before the agricultural revolution.?? After switching from a high protein, high fat, moderate carb, low toxin diet to a grain based diet, people started getting cancer.

???Thus, the switch from the ???caveman???s diet??? consisting of fat, meat and only occasionally roots, berries and other sources of carbohydrate (CHO) to a nutrition dominated by easily digestible CHOs derived mainly from grains as staple food would have occurred too recently to induce major adoptions in our genes encoding the metabolic pathways.???

Humans aren???t made to eat a grain based diet.?? I discuss this at length in the Better Baby Book, (Wiley, 2012!) and go into detail as how grains negatively effect epigenetics and our health.?? Our genes are made to respond to certain foods both positively and negatively.?? Cancer is a pretty negative response.

The researchers were smart to mention that diet isn???t the only factor in the development of cancer.?? There are other components such as ???regular physical activity, sun exposure, sufficient sleep, low chronic stress and the lack of foods that would also not have been available to our pre-neolithic ancestors.????? Okay, so diet was still the most important part.

Before you start ranting about how this only applies to high GI carbs and touting ???complex carbs??? and ???healthy whole grains???, remember that whole grains have an equal or greater insulin response to white flour.?? Regardless of the kind of grains you???re eating ??? they???re still going to produce a large insulin release.

The researchers go on to mention the importance of ???sufficient vitamin D.????? This is particularly interesting since grains deplete vitamin D stores and interfere with vitamin D absorption.?? There are even cases of people on a grain based diet developing rickets, despite adequate vitamin D intake.?? Vitamin D deficiency is yet another pathway by which grains cause cancer.

Source:http://www.bulletproofexec.com/low-carb-paleo-diets-vs-cancer-a-follow-up-note-to-steve-jobs/

Cb9a270955e2c277a02c4a4b5dad10b5

(10989)

on January 07, 2013
at 07:22 PM

consumption, cancer rates were the highest. This is in stark contrast to the fact that in populations who did not consume grains, cancer did not exist.

F5a0ddffcf9ef5beca864050f090a790

(15515)

on January 07, 2013
at 06:50 PM

What about sugar and processed grains then? I bet they are even more carcinogenic than white rice!

Cb9a270955e2c277a02c4a4b5dad10b5

(10989)

on January 07, 2013
at 07:22 PM

Yea, if I had to put my money on it then wheat would be up near the very top. I wish I could find the original paper for what I'm about to show you but all I can find are write-ups on it. "In 1843, a physician named Stanislas Tanchou spoke at the Paris Medical Society Conference. He claimed that he could predict the cancer rates in major European cities over the next 50 years. He based his predictions on the percentage of grains being consumed in each major city. What is astonishing is that, over time, his predictions turned out to be correct. In the cities that had the highest grain

Cb9a270955e2c277a02c4a4b5dad10b5

(10989)

on January 07, 2013
at 07:23 PM

consumption, cancer rates were the highest. This is in stark contrast to the fact that in populations who did not consume grains, cancer did not exist."

3
D8ac2615b6631ff22d67234adf7b6645

on January 07, 2013
at 07:01 PM

I think Jake is correct in that there isn't a single cause for most cancers. However, we can definitely stack the deck in our favor by the lifestyle choices we make. I think epigenetic factors play a huge role in whether or not we develop cancer.

One of the primary things I see in the general population is an unbalanced activation of mTOR vs AMPK pathways. Think of this as a seesaw with mTOR on one side and AMPK on the other. mTOR is our anabolic, cell-growth-promoting pathway and AMPK is our autophagy-activating, cellular cleansing, antiinflammatory-promoting pathway.

Eat too much and too often, eat low-quality foods, live a sedentary lifestyle, do not get high quality sleep, and you're setting yourself up for cancer. Excess energy for your particular activity level ---> excess insulin and IGF-1 ----> activation of PI3K ----->activation of AKT -------> activation of mTOR. This leads to a proinflammatory state through NF-kB expression, COX-2 expression, etc. This also leads to down-regulation of tumor suppressor P53. You're activating anti-apoptotic and pro-proliferative mechanisms. Essentially, like I said, if your "seesaw" is chronically tilted toward mTOR, you're setting yourself up for cancer.

Practice intermittent fasting, get high quality sleep at the appropriate time for your circadian rhythms, eat high quality food when you do eat, and exercise and you activate the AMPK pathway which induces autophagy (essentially cellular housecleaning). You're in an anti-inflammatory state. Tumor suppressor P53 is upregulated and you're helping to protect yourself from cancer.

Now, that's a very quick, down and dirty overview of two INCREDIBLY important cellular pathways. We need activation of both of them, but IN BALANCE. The coolest part is that we can directly control which pathway is activated through our lifestyle choices :-)

5bd7f43c7da83282bcb78e3aa33832e0

(266)

on January 07, 2013
at 09:41 PM

This post is brilliant! I hope you stick around!

2
C8a5c6d2804326646bb274e491f7f21b

on January 07, 2013
at 07:13 PM

For many cancers I would bet that it starts with DNA damage + a failing/suboptimal immune system. pretty much the recipe for every disease

D8ac2615b6631ff22d67234adf7b6645

on January 07, 2013
at 07:24 PM

I also agree with this. We can't prevent DNA damage and I think it's the failing/suboptimal immune system that actually allows the tumor to grow unabated.

C8a5c6d2804326646bb274e491f7f21b

(534)

on January 07, 2013
at 07:16 PM

and since when is white rice carcinogenic?

2
Ee6932fe54ad68039a8d5f7a8caa0468

(2668)

on January 07, 2013
at 05:58 PM

i really don't think there's a single cause, unfortunately. i believe that the paleo diet is a good hedge, but not a clear solution to the issue.

2
B3173217a49b5b0116078775a17eb21d

(11488)

on January 07, 2013
at 05:33 PM

A neolithic diet.

1
F5a0ddffcf9ef5beca864050f090a790

(15515)

on January 07, 2013
at 06:28 PM

I believe that cancer is caused by body malfunction on a cellular level. If I were Jack Kruze, I would come up with some long poorly explained formula such as:

C = ( NSSD x (EP + GP)) + ET + PS) - BGF

where

C - cancer NSSD - non species specific diet EP - epigenetics GP - genetic predisposition ET - environmental toxins PS - prolonged stress BGF - beneficial gut flora

Did I miss anything?

0
3ce6a0d24be025e2f2af534545bdd1d7

(26217)

on January 07, 2013
at 05:55 PM

unregulated cell growth

-2
77188106a9c27a22ad47d0ef7318de7a

(922)

on January 07, 2013
at 06:32 PM

  1. GMOs because they alter your DNA and cause cells to fire their sequences incorrectly.

  2. Refined grains and sugars as they feed cancer cells like no other.

  3. Combining fructose and omega-6 fatty acids. (Main SAD problem IMO)

  4. Incorrect food combining. (Especially blood and starch; protein and starch can't be digested properly together in the stomach as the alkaline digestive juices compete with the acidic digestive juices. This leaves you with undigested proteins in your intestines and they make it all the way to your colon where they feed unhealthy bacteria. Colon cancer much?)

194d8e8140425057fe06202e1e5822a7

(3979)

on January 07, 2013
at 10:02 PM

"GMOs because they alter your DNA" source PLEASE

A2c38be4c54c91a15071f82f14cac0b3

(12682)

on January 07, 2013
at 08:16 PM

Starch digestion occurs primarily in the SI, not the stomach, so there's no reason why you shouldn't be able digest the two macros from the same meal. There's also some evidence that combining protein and starch attenuates markers of cancer risk compared to protein alone: http://www.ncbi.nlm.nih.gov/pubmed/16410726

F5a0ddffcf9ef5beca864050f090a790

(15515)

on January 07, 2013
at 06:52 PM

Combining blood and starch... what about meat and potatoes? Aros con pollo? Pork lo mein?

77188106a9c27a22ad47d0ef7318de7a

(922)

on January 07, 2013
at 07:01 PM

Blood and starch together is terrible for you; yet it's considered to be essential for any meal to be "complete." The only way to get optimal protein digestion into amino acids in the stomach and thus absorption in the intestines is to eat your meat with vegetables and greens only. Starch and protein don't combine.

5bd7f43c7da83282bcb78e3aa33832e0

(266)

on January 07, 2013
at 09:39 PM

So are you suggesting that if I want to eat starch, I should be eating meals that are just e.g. white rice and veggies? A stir-fry perhaps?

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