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Blood test shows Globulin low, Albumin/Globulin Ratio high, Platelet count low. What does this mean? I am 50 y.o. male on paleo diet.

Answered on February 16, 2014
Created September 14, 2012 at 9:48 PM

Blood test shows Globulin low, Albumin/Globulin Ratio high, Platelet count low. What does this mean? I am 50 y.o. male on paleo diet.

Fcf272dc02cfc486fd4c5cebf540dec7

(50)

on September 16, 2012
at 11:17 PM

It does not say. Range is 2.1-3.7 g/dL; I am 1.8.

Bd271299b2d4d9b2e3da9c252fef058c

(2854)

on September 15, 2012
at 04:02 AM

which globulins are low? G? A? M?

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2 Answers

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on February 16, 2014
at 04:39 AM

Don't tell me you're on a low-carb Paleo diet and have cold fingers to boot. Look, you can't diagnose someone based on low and high. Also, just because something is within the listed reference range doesn't mean it's optimal. If you're serious about solving your issues, you need to be specific.

Low globulins often results from low immunoglobulins. When your A/G ratio is high, it could be due to low-normal Globulin and high-normal Albumin. You don't need Albumin to be abnormally high or Globulin to be abnormally low. Albumin is probably high-normal since liver enzymes are usually low on a low-carb diet. And low platelets indeed can result from being on a low-carb diet for too long, especially if you've developed autoimmune issues in the process. All the more if your WBCs are low-normal as well; they probably are. Very rarely do I see low platelets with normal or high-normal WBCs.

Go see a hematologist or rheumatologist. Depending on how low your platelets are and how low your globulin is, this could be above your PCP's pay grade. Get your antinuclear antibodies, immunoglobulins, and protein electrophoresis tested. Like the person above says, add back some starchy carbs to your diet. If you already do starchy carbs, add more.

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94480caec9fbbaacc386d86a45efa720

(1007)

on February 14, 2014
at 11:23 PM

I don't know about the globulin and albumin numbers but a low platelet count can sometimes happen on a VLC/keto diet. I see this is a pretty old post. Has anything changed for you? I was searching paleohacks for info on platelet count because mine are a point below normal from avoiding a bunch of my allergens recently. I'm pretty sure if I can get some more sweet potatoes and rice in me this week they'll come back up.

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