Top-5 for endothelian dysfunction

Answered on August 19, 2014
Created February 06, 2013 at 7:49 AM

What are top 5 non-obvious things to try for somebody with endothelian dysfunction on top of overall healthy lifestyle, paleo diet, regular exercise, and reasonable supplements?

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2 Answers


on February 06, 2013
at 10:11 AM

  1. Avoid smoking and alcohol
  2. Monitor for evidence of abnormal hypertension, cholesterol and fasting blood glucose
  3. Ensure sleep is appropriate
  4. Manage chronic stress
  5. Obtain a genetic screening test to investigate susceptibilities.

I suppose some of these are a bit obvious but worth mentioning I thought.



on February 08, 2013
at 10:42 AM


I see that you have created a new thread on this subject, so I will repeat my answer based on the information you provided in your question on blood pressure:

1) The fact that you have diagnosed Endothelial Dysfunction (ED) is very, very important. I would begin to educate myself further on this condition.

2) Are you able to provide the exact numbers of your lipid panel? Those numbers are key to see what may need to be addressed in this area.

2) Reduced levels of Nitric Oxide (NO) are key to ED. Take a look at a very interesting and recent TED talk on the role of sunlight vis a vis the release of NO from skin reserves:


So, how much sunlight are you getting on a regular basis? A suggestion has been made about a sun-bed if necessary but you need to ensure that the right UV radiation is being obtained.

3) Certain vegetables such as spinach and some lettuces are all high in NO3. Root vegetables, such as beets, are especially high and research has shown increased plasma levels of Nitrite following the consumption of beet juice.

4) I would definitely experiment with reducing your salt intake, particularly if you are adding salt to your food. It may or may not make some difference.

5) I see that your exercise program includes weights and yoga but no form of aerobic activity such as walking or running. Is this true? If so, you probably want to change that particularly if you are working in a sedentary job. More than anything else, frequent movement seems to be the key to many health issues.

6) Some supplements that have been mentioned in ED research are potassium, arginine, and antioxidants. From very preliminary scans of the research, the most promising would seem to be potassium and arginine with antioxidants not showing demonstrable results. However, you are already taking a variety of supplements and determine optimal levels of potassium and arginine would take some further research.

So, these are some preliminary things to consider and I will have more if you can provide your lipid numbers.

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