8

votes

Blood donations

Answered on September 12, 2014
Created April 23, 2011 at 4:42 PM

Hi, what are people's thoughts/experiences about donating blood, specifically the health benefits of doing so. A Dr. who's opinion I really respect and trust suggested I do it to lower my high levels of iron in my blood. I would suspect that a lot of paleo eaters have high ferratin levels.

This topic seems to be an elephant in the room. I have heard about prominent doctors who have told patients it will help with many problems including cancer but that they will not prescribe it as a treatment. The red cross will only say that giving blood is like an 'oil change' for your body. Other people have suggested that the two most beneficial things you can do for your long term health is to control insulin levels and donate blood on a semi-regular basis.

Thoughts?

edit: http://www.biomedcentral.com/1741-7015/10/54

http://cercor.oxfordjournals.org/content/early/2012/05/29/cercor.bhs139.abstract

77877f762c40637911396daa19b53094

(78467)

on October 29, 2011
at 07:10 PM

Interestingly, recent claim from italians is that Alzheimer is due to iron overload in brain due to impaired blood vehicles.

77877f762c40637911396daa19b53094

(78467)

on October 29, 2011
at 06:54 PM

How about eating nuts to boost IP6.

Ef4c5b09fdccf73be575d3a0c267fdd9

(2539)

on October 29, 2011
at 12:57 AM

Being gay doesnt have to stop you from giving blood... you just say that your not...

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on October 01, 2011
at 12:54 AM

Jack.....i wrote this long ago. Sooner or later you will be optimal. I wont give up on you. You keep posting labs and ill keep hacking you.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on October 01, 2011
at 12:52 AM

Marry a vampire or bleed your self? Leeches? Just donate.....its easier than having a period.

Af1d286f0fd5c3949f59b4edf4d892f5

(18472)

on September 30, 2011
at 09:29 PM

That's a LOT of info about exces iron Doc. I just read through this twice. Aside from giving blood, what are my other options? Is there something that can help with binding like Apolactoferrin? My labs did show a very low clearance and moderate iron saturation in the blood. (btw way.. I am not saying I won't give blood. I am just wondering if there is an equivalent option).

62ce2c6d63bb1939c2ccc0c1b41e7d86

on June 05, 2011
at 06:07 PM

I don't recall sending my letter to the editor to your website but I am glad someone did -- I'm flattered. William J. Rowe M.D. FBIS

64433a05384cd9717c1aa6bf7e98b661

(15236)

on May 29, 2011
at 06:20 AM

this is awesome and exactly what I was looking for. thanks!

64433a05384cd9717c1aa6bf7e98b661

(15236)

on April 30, 2011
at 06:14 AM

yeah that's really messed up. Senator Kerry was pushing to have that rule changed but I don't think he got very far with it. Send him an email, I often get responses from senators when I email them.

64433a05384cd9717c1aa6bf7e98b661

(15236)

on April 29, 2011
at 11:51 PM

Thanks for all the comments. I donated blood a few days ago and have been in such a good mood since. I didn't make the connection but a Dr. friend of mine told me that a euphoric feeling is common after giving blood the first time. Unfortunately it will diminish with each donation but it still feels really good. Anybody know what mechanism would be responsible for this?

6426d61a13689f8f651164b10f121d64

(11478)

on April 29, 2011
at 11:27 PM

Why do you say "plagiarized"? It comes with a citation. Are you saying the poster is an imposter, and not Dr. Rowe? If the poster really is Dr. Rowe, how can he "plagiarize" from his own website?

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:47 PM

Via de novo lipogenesis via formation of palmitic acid from carbs......and the uric acid cause disruption of the NO synthetase in vascular endothelium leading to hypertension. Both common issues in those with type two DM and insulin resistance. So your serum ferritin matters. Men can use blood donations to lower their ferritin levels if they find it high. Its a great easy and helpful way to get rid of your excess iron. Women dont tend to have this issue unless they are metabolic train wrecks of in menoapause and leptin resistant.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:44 PM

The symptoms of iron overload and anemia are very hard to differentiate between. Because of this, many times iron overload goes undiagnosed until it does major damage to the body. The number one sign is constant fatigue and lack of energy with no explanation. We commonly see this in fibromyalgia patients and over weight people and especially in diabetics. Guess what those people have to eat to get those diseases? Fructose and other carbs. Remember from Dr Lustig's lecture that the endpoint of all fructose metabolism finishes in VLDL cholesterol and uric acid. Once causes leptin resist.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:42 PM

see hemachromatosis on google for more info......

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:41 PM

Symptoms of iron overload are gastric pain, hair loss, irregular heart beat, joint pain, frequent infections, fatigue, skin discoloration, and elevated liver enzymes. If iron overload or anemia is suspected, a doctor should do a blood test before treatment. People should never take an iron supplement unless it is recommended by a doctor after a blood test has occurred. Serious consequences can occur if iron overload is mistaken for anemia and the person consumes more iron.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:39 PM

LDL cholesterol and changing it to be more damaging to coronary arteries called sdLDL. Researchers are now finding more and more incidences where too much iron accelerates many diseases.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:38 PM

When inflammation occurs in the body, free iron accumulates there and causes uncontrolled oxidation (rust is a an example oxidation) which accelerates the inflammation.See aging is really rusitng of our proteins. Its why we get wrinkles and our bones get brittle. Even though the body has natural defenses against the free iron there are many instances where the defenses do not control the iron properly. As in the case of heart disease, researchers have found that increased iron stimulates free radicals in the body which are associated with chronic diseases. Iron also contributes to affecting

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:37 PM

ron in the body is stored mainly in hemoglobin in red blood cells. Iron is also stored in myoglobin, the protein that supplies oxygen to muscles, and also in enzymes in the body. Some iron is stored in proteins to be used for future needs. Around the age of 18, excess iron begins to accumulate at about 1 milligram per day. Excess iron in the bloodstream is called unbound iron, or free iron. This free iron can build up in the body for years and can become the instigator of health problems as people age. Premature aging, cancer, osteoporosis, arthritis, diabetes, liver damage, heart disease etc

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:36 PM

Remember that fructose has the ability to increase the absorption of iron in men many fold. This is not good news for me.......cause I am a man. If I were a women I would have the built in mechanism to get rid of excess iron........you know, a period, menstruation. Girls can do that if they are menstruating. But you cant if your younger or in menopause. If you cant get rid of the iron it builds up in your body. Why is that a problem you ask?

Aead76beb5fc7b762a6b4ddc234f6051

(15239)

on April 23, 2011
at 05:39 PM

the health benefits for the recipient are legion. its the easiest way to save a life. do it.

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10 Answers

7
Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 05:32 PM

Keeping ferritin low actually is quite protective and good medical strategy but is dangerous chronically for thyroid function. The more fructose one eats the more deregulated their ferritin becomes due to small bowel absorption.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:39 PM

LDL cholesterol and changing it to be more damaging to coronary arteries called sdLDL. Researchers are now finding more and more incidences where too much iron accelerates many diseases.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:41 PM

Symptoms of iron overload are gastric pain, hair loss, irregular heart beat, joint pain, frequent infections, fatigue, skin discoloration, and elevated liver enzymes. If iron overload or anemia is suspected, a doctor should do a blood test before treatment. People should never take an iron supplement unless it is recommended by a doctor after a blood test has occurred. Serious consequences can occur if iron overload is mistaken for anemia and the person consumes more iron.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:47 PM

Via de novo lipogenesis via formation of palmitic acid from carbs......and the uric acid cause disruption of the NO synthetase in vascular endothelium leading to hypertension. Both common issues in those with type two DM and insulin resistance. So your serum ferritin matters. Men can use blood donations to lower their ferritin levels if they find it high. Its a great easy and helpful way to get rid of your excess iron. Women dont tend to have this issue unless they are metabolic train wrecks of in menoapause and leptin resistant.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:37 PM

ron in the body is stored mainly in hemoglobin in red blood cells. Iron is also stored in myoglobin, the protein that supplies oxygen to muscles, and also in enzymes in the body. Some iron is stored in proteins to be used for future needs. Around the age of 18, excess iron begins to accumulate at about 1 milligram per day. Excess iron in the bloodstream is called unbound iron, or free iron. This free iron can build up in the body for years and can become the instigator of health problems as people age. Premature aging, cancer, osteoporosis, arthritis, diabetes, liver damage, heart disease etc

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:36 PM

Remember that fructose has the ability to increase the absorption of iron in men many fold. This is not good news for me.......cause I am a man. If I were a women I would have the built in mechanism to get rid of excess iron........you know, a period, menstruation. Girls can do that if they are menstruating. But you cant if your younger or in menopause. If you cant get rid of the iron it builds up in your body. Why is that a problem you ask?

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:42 PM

see hemachromatosis on google for more info......

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:44 PM

The symptoms of iron overload and anemia are very hard to differentiate between. Because of this, many times iron overload goes undiagnosed until it does major damage to the body. The number one sign is constant fatigue and lack of energy with no explanation. We commonly see this in fibromyalgia patients and over weight people and especially in diabetics. Guess what those people have to eat to get those diseases? Fructose and other carbs. Remember from Dr Lustig's lecture that the endpoint of all fructose metabolism finishes in VLDL cholesterol and uric acid. Once causes leptin resist.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 23, 2011
at 08:38 PM

When inflammation occurs in the body, free iron accumulates there and causes uncontrolled oxidation (rust is a an example oxidation) which accelerates the inflammation.See aging is really rusitng of our proteins. Its why we get wrinkles and our bones get brittle. Even though the body has natural defenses against the free iron there are many instances where the defenses do not control the iron properly. As in the case of heart disease, researchers have found that increased iron stimulates free radicals in the body which are associated with chronic diseases. Iron also contributes to affecting

64433a05384cd9717c1aa6bf7e98b661

(15236)

on May 29, 2011
at 06:20 AM

this is awesome and exactly what I was looking for. thanks!

Af1d286f0fd5c3949f59b4edf4d892f5

(18472)

on September 30, 2011
at 09:29 PM

That's a LOT of info about exces iron Doc. I just read through this twice. Aside from giving blood, what are my other options? Is there something that can help with binding like Apolactoferrin? My labs did show a very low clearance and moderate iron saturation in the blood. (btw way.. I am not saying I won't give blood. I am just wondering if there is an equivalent option).

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on October 01, 2011
at 12:52 AM

Marry a vampire or bleed your self? Leeches? Just donate.....its easier than having a period.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on October 01, 2011
at 12:54 AM

Jack.....i wrote this long ago. Sooner or later you will be optimal. I wont give up on you. You keep posting labs and ill keep hacking you.

77877f762c40637911396daa19b53094

(78467)

on October 29, 2011
at 06:54 PM

How about eating nuts to boost IP6.

6
E5a41bcb2819c818cc0d92489e7c35f2

on April 30, 2011
at 04:53 AM

I don't give blood because the FDA dictates that nobody wants mine ??? their antiquated rules about gay men's blood being unfit for the public supply still stand. Hearing about the health benefits makes me even more annoyed that, unlike many other organizations and countries, the FDA hasn't gotten with the times.

64433a05384cd9717c1aa6bf7e98b661

(15236)

on April 30, 2011
at 06:14 AM

yeah that's really messed up. Senator Kerry was pushing to have that rule changed but I don't think he got very far with it. Send him an email, I often get responses from senators when I email them.

Ef4c5b09fdccf73be575d3a0c267fdd9

(2539)

on October 29, 2011
at 12:57 AM

Being gay doesnt have to stop you from giving blood... you just say that your not...

2
62ce2c6d63bb1939c2ccc0c1b41e7d86

on April 29, 2011
at 09:50 PM

American J. Cardiology 86:256, 2000

Our Ancestors Had It Right

Mary Hanudel-Larsson's stress test.

The absorption of just the right amount of iron through the intestine (duodendum) might have provided significant cardiovascular advantages to early man, the Masai of today, and conceivably has been advantageous to an extraordinary urban athlete. Excess iron may be more detrimental than iron deficiency, because high iron levels can lead to the formation of highly reactive hydroxyl radicals and lipid peroxidation, conducive to early atherosclerosis. Furthermore, there must be enough protein in the diet to sequester iron.(1)

But can we, with our modem diet and often iron supplements, establish a proper balance? Before the development of the crudest of weapons, early man probably survived by chasing his "lean meat," until the animal dropped from exhaustion, probably even during the hot. dry seasons.(2) It is conceivable that early man supplemented water scarcities with the blood of his prey. This is supported by observations of today's Masai of East Africa who drink 3 to 5 quarts of cow's milk daily, but during the dry season of 4 to 5 months, ingest fresh cow blood, mixed (balanced) with milk. Yet the Masai have minimal atherosclerosis (3) and are talented endurance athletes.

Might the consumption of animal blood in the form of "blood pudding" simulate the apparent advantages of the Masai food intake? The case of 40-year-old Mary Hanudel-Larsson suggests this possibility. Larsson was studied by me in Toledo, Ohio, soon after having won the USA title of Ultramarathoner of the Year in 1987. At the time of my study, she was running 30 km/ day, preparing for an upcoming 1,000-km race in Australia, but was plagued with numerous stress fractures, intermittent amenorrhea, and pronounced stress-related gastrointestinal bleeding. Subsequently, a magnesium-loading test (4) indicated severe magnesium deficiency, which may adversely affect the homeostatic regulation of iron.(5)

In the early 1990s she moved to Sweden, and soon adapted a Swedish custom, ingesting rich blood pudding containing cow's blood (as with the Masai), but mixed with flour and fat, consuming during heavy training over 500 g/week up to now. The amenorrhea completely subsided along with cessation of stress fractures despite a persistent exercise program of 120 to 150 km of running each week, swimming, and rowing-machine training, totaling 15 to 20 hours/week. In 1997, Larsson won a 24-hour USA race (213 km), and in that year and also in 1998 set new course records in Japan in 250-km races. There has been no requirement for correction of anemia since moving to Sweden.

William J. Rowe, MD Swanton, Ohio 28 March 2000

  1. Andrews NC. Disorders of iron metabolism. N Engl J Med 1999:341:1986-1995.
  2. Carrier DR. The energetic paradox of human running and hominid evolution. Anthropology 1984;25:483-495.
  3. Ho KJ. Biss K, Mikhelson B, Lewis LA. Taylor B. The Masai of East Africa: some unique biological characteristics. Arch Pathol 1971:91:387-410.
  4. Rowe WJ. Extraordinary unremitting endurance exercise and permanent injury to normal heart. Lancet 1992:340:712-714.
  5. Kimura M. Yokoi K. Iron accumulation in tissues of magnesium-deficient rats with dietary iron overload. Biol Truce Elem Res 1996:51:177-197.

1
Medium avatar

(12379)

on April 23, 2011
at 08:54 PM

I donate blood as often a I can (every 56 days). I haven't really thought much about the effect on my body. I feel fine after every donation as long as I have a snack and hydrate and avoid strenuous activity the rest of that day.

My thoughts are that I would really want someone to do it for me or my family if we were in need. It's only 1 hour out of my day and it does a world of difference.

1
8f4ff12a53a98f3b5814cfe242de0daa

(1075)

on April 23, 2011
at 05:26 PM

The first time I came across this was a mention from Steven Fowkes (older than Paleo dietary movement, but generally dislikes grain, thinks the modern diet degenerates the populations health). He mentioned that donating blood was a good way to remove iron, which is supposed to be a strong source of free radical damage. So his work might be a decent start on this.

In addition, the notion that items like blueberrys / anthocyanins containing items are good mainly rests on their ability to bind to iron (aka form chelates) and prevent damage. But if you have to much iron, it might be a good idea to remove it, seeing as how iron itself definitely has downsides.

http://www.sciencedaily.com/releases/2010/12/101208083541.htm

Aside from that, donating blood is helpful for those who need it. So it is a win/win situation.

0
Da3d4a6835c0f5256b2ef829b3ba3393

on October 29, 2011
at 12:18 AM

Donate blood.

Much upside. Little to no downside.

0
5edbf85deaf83e13b176df023abb154d

on April 29, 2011
at 10:46 PM

The "Rowe" post was plagiarized from here: http://www.femsinspace.com/ancestors.htm

6426d61a13689f8f651164b10f121d64

(11478)

on April 29, 2011
at 11:27 PM

Why do you say "plagiarized"? It comes with a citation. Are you saying the poster is an imposter, and not Dr. Rowe? If the poster really is Dr. Rowe, how can he "plagiarize" from his own website?

62ce2c6d63bb1939c2ccc0c1b41e7d86

on June 05, 2011
at 06:07 PM

I don't recall sending my letter to the editor to your website but I am glad someone did -- I'm flattered. William J. Rowe M.D. FBIS

0
A68f24168bc0de414a038037e287b581

on April 24, 2011
at 12:11 AM

I remember hearing on the benefits of blood donation as a means to get rid of the excess iron from Dr. Sharon MOalem (author of "Survival of the Sickest"). He was convinced that a lot of diseases (Alzheimer and cancers) "feed" on iron.

Other point I remember reading/hearing somewhere, was that our bodies evolved to accommodate constant parasites, which fed on our blood. So now, when we live with no parasites for the most part, thanks to modern medicine and hygiene, we overproduce iron and other components, so it's beneficial to let some of it go.

That's why in ancient time letting blood was so popular, b/c they noticed that sometimes it was really helpful and healing... problem is they used ax where scalpel was needed...

I haven't done my blood works in a while, but last time, after over 6mo of paleo and high meat consumption, I still was anemic and had low iron levels. Go figure... :)

77877f762c40637911396daa19b53094

(78467)

on October 29, 2011
at 07:10 PM

Interestingly, recent claim from italians is that Alzheimer is due to iron overload in brain due to impaired blood vehicles.

0
79648d1e9f1a8d25d9450a8a1d18fe64

(395)

on April 23, 2011
at 08:31 PM

This is discussed in Protein Power Lifeplan by the Eades...the human body naturally holds on to as much iron as possible. The Eades hypothesize that most early humans probably carried parasites that would consume small amounts of blood thus keeping iron levels in check. In our sterilized, modern world this is not a prevalent problem and men especially can have iron levels that are excessive which then affects and depletes magnesium. For men, in particular, they recommend regular blood donation. For women that are still having a menstrual cycle it's not a much of a problem but they can donate if they wish.

0
535633b57c4a4940d1e913e7a12ee791

(1013)

on April 23, 2011
at 04:46 PM

................

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