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How much influence do recent meals have on the amount of water-soluble in one's blood?

Answered on August 19, 2014
Created July 22, 2013 at 12:35 PM

Hi folks, after reading this article ( http://www.westonaprice.org/dentistry/invisible-toothbrush ) on the connection between ascorbic acid and poor dental health, I'm wondering of how much value the measured Vit C content in the subject's blood really is as the body does not have the ability to store Vit C.

Hence, if one eats 100 grams of fresh leafy greens (or a random high Vit C food), one would probably have a high Vit C score in a blood test taken 12 hours later and if the same person would get a test one week later after eating 100 grams of potato chips (or a random low Vit C food) 12h before the test the results would probably show that he has low Vit C concentrations.

Is that right?

I couldn't find a satisfying answer on Google so I hope that you can confirm that my line of thoughts is right.

Thanks a lot!

32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on July 22, 2013
at 05:22 PM

Vitamin C is recycled. Vitamin C is oxidized to dehydroascorbate in its use, but our bodies reduce it back to ascrobate instead of simply eliminating it as waste. That's why our needs are so low versus other animals.

A0c49f398499246c623e6527e9dd5ca2

(548)

on July 22, 2013
at 03:00 PM

Thanks for your answer but looking at the graph that shows the concentration with a 200mg dose in figure 1 I wonder how the body maintains the levels of Vit C at 75 micromol\l what seems to be a constant level. Does it actually decline slowly? Is the body able to store some Vit C in an organ and release it gradually? Also, was this study performed in humans? Does the 'maintenance level' differ greatly between individuals?

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32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on July 22, 2013
at 01:13 PM

In terms of vitamin C: Our bodies do not like having excess vitamin C in circulation. If you megadose vitamin C, you get a spike in ascorbate concentrations, but that quickly is eliminated by the body. We have biochemical machinery in place that recycles spent vitamin C, which is why our vitamin C needs are low. Vitamin C itself is a rather reactive molecule, so you don't want too much of it floating around reacting willy-nilly with whatever proteins it finds.

Here's the pharmacokinetics of vitamin C:

how-much-influence-do-recent-meals-have-on-the-amount-of-water-soluble-in-one's-blood?

You can see that you can keep it elevated by large frequent doses orally, but it wants to trend back to the baseline rather quickly. Even more pronounced is when you administer it IV. You get a huge unnatural spike that our bodies quickly eliminate.

32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on July 22, 2013
at 05:22 PM

Vitamin C is recycled. Vitamin C is oxidized to dehydroascorbate in its use, but our bodies reduce it back to ascrobate instead of simply eliminating it as waste. That's why our needs are so low versus other animals.

A0c49f398499246c623e6527e9dd5ca2

(548)

on July 22, 2013
at 03:00 PM

Thanks for your answer but looking at the graph that shows the concentration with a 200mg dose in figure 1 I wonder how the body maintains the levels of Vit C at 75 micromol\l what seems to be a constant level. Does it actually decline slowly? Is the body able to store some Vit C in an organ and release it gradually? Also, was this study performed in humans? Does the 'maintenance level' differ greatly between individuals?

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