Taking B12 while already high in blood

Answered on September 03, 2013
Created September 01, 2013 at 6:47 PM

I am suffering from adrenal fatigue, also some starting problems with thyroid (tsh value on the high border, t3 and t4 normal). I also have leak gut.

My nutritional practitioner recommended me taking high doses of b vitamin complex (on average 700% RDA daily). When I take B vitamins tablet, I feel on the same day positive difference in mood. I also noticed that it improves my gut health a bit.

Anyway this makes me confused because before I started taking it I made blood test twice and every time it showed that my b12 is high, b9 is normal at good values. I am worried that if I am already high of B vitamins, could make in long term any negative side effects? But if I am already high, why I feel better when taking it? Does any body have any clue, idea about it?

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2 Answers


on September 03, 2013
at 12:48 PM

Most RDA recommendations are woefully in need of revision. Perhaps your B complex has Folate instead of folic acid (important for MTHF polymorphisms). That B vitamin could help your BH4 cycle provide substrate for the pathways needed for the production of serotonin, dopamine, etc. which do affect mood.

There are lots of reasons a good B complex could help you and its very unlikely you are going to overdose on any of the B's. You might consider SAMe as well, it sounds like you can utilize additional methyl donors. Eggs would be good too.

Here is an example of a good B complex formula;

Thiamin (as Thiamin HCl) 110 mg. Riboflavin (as Riboflavin 5'-Phosphate Sodium) 10 mg. Niacin (130 mg as Niacinamide and 10 mg as Niacin) 140 mg. Vitamin B6 (as Pyridoxal 5'-Phosphate) 10 mg. Folate (as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 400 mcg. Vitamin B12 (as Methylcobalamin) 400 mcg. Biotin 400 mcg. Pantothenic Acid (as Calcium Pantothenate) 110 mg. Choline Citrate 80 mg.



on September 02, 2013
at 02:12 PM

Whats your homocysteine, the B12 might not reach your cells very well.

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