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Will Autoimmune Vaccines Be the Next Big Thing?

Answered on August 19, 2014
Created November 14, 2010 at 3:00 AM

Looks like they are working on a 'vaccine' for autoimmune induced (ie type I) diabetes: http://www.businessweek.com/lifestyle/content/healthday/637852.html Already I see the potential for this to be the next medication that much of America will end up taking for life. If this tech works, it will most likely be extended to all kinds of autoimmune diseases like hypothyroid and arthritis. Might even work for poison ivy! But will it work as directed? Will it really be as precisely targeted as advertised? What kind of side effects should we expect from this nanotechnology? And as much as those suffering from autoimmune problems may need this right now, won't this direction also in many ways potentially distract us from targeting prevention or cure of the problem instead of just lifetime containment? But of course, big pharma does so love to develop medications that are required for the lifetime of the individual!

62ed65f3596aa2f62fa1d58a0c09f8c3

(20807)

on November 14, 2010
at 06:12 AM

Diamyd is already in phase III trials on humans. Earlier human trials have shown strong benefits plus supposedly no major side effects. So far, it's looking interesting

62ed65f3596aa2f62fa1d58a0c09f8c3

(20807)

on November 14, 2010
at 04:19 AM

Well, the body could easily generate more so I don't think it would be permanent alteration, but I do agree that any intervention would probably alter immunity for other things. On the flip side, immune system of the body overlap and if the therapy is specific enough, then it may be that other immune functions could mostly make up for the weakness in the one area targeted. Maybe.

5841391284e7af8c495c54bd90d3a795

(2764)

on November 14, 2010
at 04:13 AM

Oy! Sounds like it's time to invest. Sheesh! If the immune system cells that are targeted are removed what will take their place in our defenses or what will afflict us that they would have protected us from?

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205ee1b02dc8252a50edd5508adbad49

on November 14, 2010
at 05:02 AM

Let's hope something comes of this cure.

Or this one-- http://www.lctglobal.com/Product-Pipeline/Diabecell/

Or this one-- http://www.faustmanlab.org/

Every couple years there is news for a new Type 1 diabetes cure.. But nothing ever seems to come of it. Sadly, there is no money in curing us T1D.. But lots of money in treating us!

By the way, today (14 Nov) is World Diabetes Day! Will shamelessly plug my blog, since there is some interesting diabetes related stuff there-- www.andariegoblog.blogspot.com

62ed65f3596aa2f62fa1d58a0c09f8c3

(20807)

on November 14, 2010
at 06:12 AM

Diamyd is already in phase III trials on humans. Earlier human trials have shown strong benefits plus supposedly no major side effects. So far, it's looking interesting

0
1145a340276b66b7765d7808128062ea

(80)

on November 21, 2011
at 01:52 PM

Looks like Diamyd did not work out in this trial, and further trials were stopped.

http://www.diamyd.com/docs/diamydType1.aspx?section=products

That being said, vaccines have promise. Here is an recent article describing 10 promising vaccines, all cancer oriented (alas).

http://www.fiercevaccines.com/special-reports/10-promising-therapeutic-vaccines

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