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Acetate as fuel in heavy drinkers?

Commented on June 29, 2014
Created June 28, 2014 at 12:40 AM

According to latest research, acetate is used as primary fuel in heavy drinkers.

Here are details: Science! They say, dependence on alcohol raises because of acetate circulating the body which is really easily available fuel for the body.

My question is: what if acetate is introduced into bloodstream of a heavy drinker? This should trigger the same reaction except acetaldehyde poisoning. This could help fighting alcoholism.

What do you think?

96440612cf0fcf366bf5ad8f776fca84

(19463)

on June 29, 2014
at 05:22 PM

Fair enough

0ba891d22837788c4d5ccf3f33f60329

(30)

on June 28, 2014
at 05:52 PM

Actually acetate is a 2 carbon carboxylic acid, while acetone is a 3 carbon ketone whose anion would be different than acetate. Acetone's anion would have a CH2 group where acetic acid has an O group. Just sayin'.

F291857fa12a0291688ea994343156dc

(720)

on June 28, 2014
at 05:25 PM

Because some people have a hard understanding a simple question & formulating a cogent response? :(

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on June 28, 2014
at 01:21 PM

Why didn't you address my question? Because it's off-topic?

568a63417a8ab71b711630072ae8c602

(0)

on June 28, 2014
at 02:09 AM

This is so stupid that you closed the question!

Alcohol metabolism is vital for anybody. And alcohol is paleo too.

Tell me what was the real reason for closing my question?

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on June 28, 2014
at 01:50 AM

Ok, now, why is this on-topic for Paleohacks? Feel free to edit your post above… if it's on topic, we can reopen it.

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on June 28, 2014
at 01:00 AM

Fix your link. :)

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3 Answers

0
F291857fa12a0291688ea994343156dc

(720)

on June 28, 2014
at 05:22 PM

The metabolism of alcohol is WAY outside my areas of expertise...

Here's some anecdotal info

I have a friend who drinks a LOT.

Between beer (beer or malt liquor), vodka & red wine.. in a typical day he consumes the equivalent of about 22 - 1oz servings of 60 proof alcohol.

He also eats a modest lunch (maybe a sandwich) & a reasonable dinner (meat & more salads & veggies since he's tried to eat more like me)

He's a big guy 6' 3" ~260.... (huge gut).

I got him squeezing lemons & limes into his beer & vodka drinks. He consumes the juice of ~4 or 5 lemons per day.

He functions well...until maybe after dinner when he's pretty drunk. We used to share the same internist who seemed to theorise that "some people can just run on alcohol". YMMV

0
96440612cf0fcf366bf5ad8f776fca84

(19463)

on June 28, 2014
at 01:14 PM

I'm reopening this since what the OP asks is actually a hack in the spirit of paleohacks, and interestingly enough acetate is an anion of acetone, which is a ketone. So perhaps alcoholics are indirectly using a ketone.

0ba891d22837788c4d5ccf3f33f60329

(30)

on June 28, 2014
at 05:52 PM

Actually acetate is a 2 carbon carboxylic acid, while acetone is a 3 carbon ketone whose anion would be different than acetate. Acetone's anion would have a CH2 group where acetic acid has an O group. Just sayin'.

0
56c28e3654d4dd8a8abdb2c1f525202e

(1822)

on June 28, 2014
at 01:28 AM

One wonders then if a high resistant starch diet (or high inulin, or high pectin) is useful for detox.

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