1

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Retinol and Acne

Answered on August 19, 2014
Created February 24, 2013 at 4:47 AM

I took a spectracell test and was found to be deficient in glutathione and retinol. I have begun taking retinol drops (10000 units per day) and also N-acetylcysteine. I was wondering if the vitamin a would clear up my acne, and if so after how long? Anybody have any similar experience?

F20af1e0c77eff221d556e3db0fc5684

(248)

on June 09, 2013
at 03:41 AM

hardeepsura, I'm in the camp that suspects vitamin A dosage varies with metabolic rate, light exposure, etc. That said, I'm experimenting with 2-3 pills of NOW Foods Vitamin A daily, which obviously wouldn't be recommended due to toxicity.

Adb6852b4f2f42904da67708ffcd59f5

(501)

on May 30, 2013
at 08:30 PM

I agree +1 how much retinol?

Adb6852b4f2f42904da67708ffcd59f5

(501)

on May 30, 2013
at 08:27 PM

Sorry but when did keratosis form by vitamin A toxicity. From what i heard, a lot of hackers claim increasing vitamin A has helped control it/clear it up?

F20af1e0c77eff221d556e3db0fc5684

(248)

on February 26, 2013
at 12:05 AM

I've gone on/off retinol several times, and never had an initial breakout. I just had fewer new pimples.

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 25, 2013
at 03:32 AM

i take plenty of zinc and i wasnt deficient, although im not sure about my stomach acid.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on February 25, 2013
at 03:07 AM

as you mentioned acne, it may be worth you doing a zinc taste test (tally test) to see if you are deficient in zinc. if you are low in zinc you may also have low stomach acid. more info here, http://digitalnaturopath.com/cond/C288489.html & http://digitalnaturopath.com/cond/C42513.html

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 25, 2013
at 03:00 AM

That being said, I do think it is good for my skin so far, as it seems smoother. Would there be an initial breakout for vit. A?

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 25, 2013
at 02:59 AM

Its been 4 days so far, not much improvement, but ill keep your experience in mind.

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 25, 2013
at 02:50 AM

my vitamin k levels are very high, that is a good point though. I will make sure to supplement vit d as i always have.

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 24, 2013
at 05:33 AM

And maybe you misunderstood my question, according to the Spectracell test I am DEFICIENT. I am not jacking up my vitamin a to reduce acne but simply to have normal levels of retinol in my body. That may or may not clear my acne, that was my question. I get pretty tired of people saying go to a doc who knows only slightly more about the condition than I do. I went to a dermatologist last week, but the guy knew nothing about vitamin deficiencies and acne, and also he knew nothing about antioxidant function as it relates to acne... Nice guy though

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 24, 2013
at 05:27 AM

I dont know about that... what if my retinol levels become normal? Will I see improvement at that point? I did do accutane, it worked for the time being but not for long. No point in trying that again unless it was at a long term low dose.

4bd4e2fe6a095663f80c69656936e487

(744)

on February 24, 2013
at 05:16 AM

See what happens in a week.

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3 Answers

1
543a65b3004bf5a51974fbdd60d666bb

(4493)

on February 25, 2013
at 02:39 AM

Make sure your Vitamin D3 level is good as well, or supplement.

Supposedly (all refs listed below) Vitamin D is protective against Vitamin A toxicity (& vice versa).
Its all one big balancing act, Vitamin K is part of the equation as well.

Refs:
Is Vitamin A Toxicity a Concern
Tufts University Confirms That Vitamin A Protects Against Vitamin D Toxicity
Vitamin D Protects Against the Toxicity of Vitamin A
New Evidence of Synergy Between Vitamins A and D
Is Vitamin D Safe? Still Depends on Vitamins A and K
Imbalances Between Vitamins A and D Lead To Toxicity

543a65b3004bf5a51974fbdd60d666bb

(4493)

on February 25, 2013
at 03:07 AM

as you mentioned acne, it may be worth you doing a zinc taste test (tally test) to see if you are deficient in zinc. if you are low in zinc you may also have low stomach acid. more info here, http://digitalnaturopath.com/cond/C288489.html & http://digitalnaturopath.com/cond/C42513.html

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 25, 2013
at 02:50 AM

my vitamin k levels are very high, that is a good point though. I will make sure to supplement vit d as i always have.

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 25, 2013
at 03:32 AM

i take plenty of zinc and i wasnt deficient, although im not sure about my stomach acid.

1
F20af1e0c77eff221d556e3db0fc5684

on February 25, 2013
at 01:47 AM

Keeping PaleoGreyhound's warning in mind, I find that I notice acne severity lessening within a week of increasing retinol.

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 25, 2013
at 03:00 AM

That being said, I do think it is good for my skin so far, as it seems smoother. Would there be an initial breakout for vit. A?

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 25, 2013
at 02:59 AM

Its been 4 days so far, not much improvement, but ill keep your experience in mind.

F20af1e0c77eff221d556e3db0fc5684

(248)

on February 26, 2013
at 12:05 AM

I've gone on/off retinol several times, and never had an initial breakout. I just had fewer new pimples.

Adb6852b4f2f42904da67708ffcd59f5

(501)

on May 30, 2013
at 08:30 PM

I agree +1 how much retinol?

F20af1e0c77eff221d556e3db0fc5684

(248)

on June 09, 2013
at 03:41 AM

hardeepsura, I'm in the camp that suspects vitamin A dosage varies with metabolic rate, light exposure, etc. That said, I'm experimenting with 2-3 pills of NOW Foods Vitamin A daily, which obviously wouldn't be recommended due to toxicity.

0
62442eec80b7d248ccfa08f98f736748

on February 24, 2013
at 05:10 AM

in general, the amount of retinol needed to diminish acne puts u at risk for vit A toxicity...which can be pretty nasty -> keratosis, hepatotoxicity -> cirrhosis or hepatitis, alopecia... that's why isoretinoin was designed as a RX drug. it is a vit a derivative that is prescribed to tx acne. it's mech of action is still unclear but probably related to specific targeting of sebaceous gland epithelium. in general though, vit a induces differentiation of epithelial cells which is what led to the development of all trans retinoic acid which is FDA-approved for acute promyelocytic leukemia treatment...and why vit a in general shows activity against acne. go to ur doc and get a RX. jacking up the vit A to try to clear your acne doesn't seem like a very smart idea...

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 24, 2013
at 05:33 AM

And maybe you misunderstood my question, according to the Spectracell test I am DEFICIENT. I am not jacking up my vitamin a to reduce acne but simply to have normal levels of retinol in my body. That may or may not clear my acne, that was my question. I get pretty tired of people saying go to a doc who knows only slightly more about the condition than I do. I went to a dermatologist last week, but the guy knew nothing about vitamin deficiencies and acne, and also he knew nothing about antioxidant function as it relates to acne... Nice guy though

5dbc84fc8a8e78e4db7293b58efdde32

(120)

on February 24, 2013
at 05:27 AM

I dont know about that... what if my retinol levels become normal? Will I see improvement at that point? I did do accutane, it worked for the time being but not for long. No point in trying that again unless it was at a long term low dose.

Adb6852b4f2f42904da67708ffcd59f5

(501)

on May 30, 2013
at 08:27 PM

Sorry but when did keratosis form by vitamin A toxicity. From what i heard, a lot of hackers claim increasing vitamin A has helped control it/clear it up?

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