2

votes

First-15-months-of-Paleo labs ... TSH, Cholesterol, C-RP better; Liver, Kidney, Glucose, Vit D worse?

Answered on August 19, 2014
Created June 13, 2012 at 2:46 AM

Hello, I'm a longtime lurker, first-time asker.

15 months ago, as I was starting my experiment with Paleo, I had some labs done; figured I was overdue for a follow-up.

Here are the highlights, or anything Out Of Range (OOR), either then or now. (I can share any other numbers if requested.):


3/20/2011 (11:30 am) -> 6/7/2012 (10:00 am) (Both fasted at least 14 hours.)

Glucose 84 -> 91

BUN 10 -> 10 Creatinine 0.84 -> 0.87 eGFR >59 -> 114 Calcium 9.6 -> 9.6

Phosphorus 3.5 -> 4.7 (OOR)

Bilirubin 1.3 (OOR) -> 1.6 (more OOR)

AST 25 -> 30 ALT 15 -> 27

Cholesterol, Total 150 -> 263 Triglycerides 53 -> 52 HDL 45 -> 92 LDL Calc 94 -> 161

TSH 7.76 (OOR) -> 3.6 ... T4, T3 Uptake, FTI all within range both times, but just a tick lower now.

Thyroxine (T4) 6.4 -> 6.1 T3 Uptake 38 -> 36 Free Thy Index 2.4 -> 2.2

Urine Ketones 3+ (OOR) -> 3+ (To be expected, I think.)

Vitamin D 28.6 (OOR) -> 25.4 (more OOR!)

C-Reactive Protein, Cardiac 0.74 -> 0.16

Hemoglobin A1c 5.5 (111 est. avg) -> [didn't test]

Iron w TIBC All in range -> [didn't test]

All else was and is within range.


VAP

LDL 164 (OOR) HDL 81 VLDL 14

T Cholesterol 259 (OOR) Triglycerides 56 Non HDL Chol 178 (OOR)

apoB100-calc 111 (OOR)

LDL-R (Real)-C 139 (OOR) Lp(a) C 16.0 (OOR)

IDL C 9 Remnant Lipo 17 Probably Metabolic Syndrome No

HDL-2 30 HDL-3 52 VLDL-3 8

LDL1 A 20.8 LDL2 A 55.1 LDL3 B 57.2 LDL4 B 5.7

LDL Density Pattern A


About Me

Male 6' 32yo 140lbs (yes, pretty thin, but have always been towards the bottom of BMI scale, but newly determined to put on weight.)

Question

Any general/specific feedback is appreciated. Just wondering if there's anything one can infer from these results. Any advice? Lab tests to consider in the future? Symptoms, etc., to watch out for?

Particularly in regards to:

  • Thyroid. I think TSH is still OOR by Paleo standards, but I assume improvement without medication or much iodine to speak of (as it exacerbated acne) is a good sign, or not?

  • Liver Enzymes. I think elevated by Paleo standards. Worth further examination? Any ideas why Paleo would increase them? Gallstones?

  • Kidney. What's up with elevated Phosphorus? A fluke? My records show I've been getting ~90% of RDA, and I don't supplement.

  • Glucose. I bought a glucose meter and will be testing fasted and postprandial numbers in the coming days.

  • Balanced approach going further. Given results, current ailments (particularly acne) and objective of gaining weight, what's my best course of action to balance all these things?


Background

After a few weeks' transition into Paleo, and as of a few days before 3/2011 labs, I was basically full-fledged Paleo, consuming:

  • 1900 calories
  • 40g carbs
  • 100g of protein
  • 150g of fat (mostly cream, chicken, 4x egg yolks; 40g saturated)
  • BP: ~112/72

Between 3/2011 and 3/2012

There was plenty of experimentation (in many cases for the worse), but roughly averaged:

  • 1900 calories
  • 75g carbs (mostly banana, berries, coconut milk, veggies, leafy greens)
  • 80-100g protein (primarily from 8oz GF beef, 4x pastured egg yolks)
  • >190g (65%) fat (mostly coconut milk (~1 can/day), coconut oil, egg yolks; 2-3g O3; <8g O6; >90g saturated)
  • 4,0000 IU Vitamin D
  • B Complex (Vitamin Shoppe liquid, probably not best quality)
  • Fermented Cod Liver Oil
  • No: nightshades, dairy, mushrooms, egg whites
  • started drinking a few cups of coffee in January; stopped in March

As of 3/2012 (last three months)

  • 2500 calories
  • 75g carbs (mostly white rice; got rid of FODMAPs)
  • 80-100g protein (primarily from 8oz GF beef, 6x egg yolks, some chicken)
  • >200g (75%) fat (mostly coconut oil, egg yolks, beef; 2-3g O3; <7g O6; >130g saturated)
  • strength training 3x/week; 30min noontime walks a few times a week
  • stopped: coconut milk (replaced with more coconut oil via homemade mayo)
  • added: homemade bone broth (from chicken feet), 4oz beef liver/week and water kefir, vitamin c, magnesium citrate, zinc picolinate
  • 2,000 IU Vitamin D (I thought I might've been overdoing it, but apparently not.)
  • Body Temp (sublingual): ~36.35/97.43 waking; ~36.61/97.89 daytime average (random times/days); high of 36.9/98.42

In the last three months, I've gained back 1lb/wk after realizing I was quite underweight (127 lbs) due to not wanting to overdo anything. Now planning to maintain this trajectory (3x/wk workouts, 500 addition calories per day) until I hit 180lb, hopefully.

In the last week, I have:

  • day before blood draw:
  • started a targeted ketogenic diet; ~20g carbs four times a week; 55g (difference from honey pre-workout) on workout days
  • eliminated: fermented cod liver oil; white rice replaced with fewer carbs via leafy greens, carrots, garlic
  • after blood draw:
  • added: 1/2tsp dulse to get 100% iodine; i will proceed with caution from here without a full thyroid panel, but so far pretty good
  • upped: Vitamin D to 2x 5,000IU doses
  • BP: 124/75

I've since seen my body temp jump a notch: 36.9/98.42 (+0.55/0.9) waking (only measured once so far), high of 37.05/98.69; 37/98.6 daytime average from three random readings.

Ailments (motivators to try Paleo) and results thus far

  • acne (with rosacea perhaps?) - drastically improved and diminished, but still a nuisance and healing; worse with more carbs, fruit or dairy
  • dandruff - gone, but reappears, likewise, with more carbs, fruit or dairy
  • brittle, yellow big toenails, esp. left - much healthier, stronger; ridged, but improving still
  • also some neuropathy in left leg (at least partially caused by benign brain thing and sedentary lifestyle) - much improved with workouts and walks

Thanks for reading! If you didn't, that's OK. If you have a question, just ask if you don't want to hunt down a possible answer above.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 24, 2012
at 03:08 PM

Interesting; thanks, Mambo.

5e92edc5a180787a60a252a8232006e9

(345)

on June 20, 2012
at 02:40 AM

http://www.ncbi.nlm.nih.gov/pubmed/7760967

5e92edc5a180787a60a252a8232006e9

(345)

on June 19, 2012
at 02:27 PM

Here's an article, a bit dated, showing that short-term hypothyroidism which lowers T3 can increase both LDL AND LP(a). The T3 angle looks promising.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 15, 2012
at 04:21 AM

Thanks, Mambo. I'll look further into the things you mentioned, and do a more thorough thyroid panel next time around. Getting ~100mcg selenium and 100% iodine currently, but will add a supplemental ~125mcg of selenium starting tomorrow, and double iodine once per month.

5e92edc5a180787a60a252a8232006e9

(345)

on June 14, 2012
at 11:15 PM

I'd definitely get the straight dope on your HT, check FT3 and RT3. Ur already on selenium so start Iodine very slowly in small increments like PHD says and then see whether your LDL and Lpa fall. I have a feeling it might.

5e92edc5a180787a60a252a8232006e9

(345)

on June 14, 2012
at 11:13 PM

That LP(a) range can be very confusing. For VAP tests, I believe you have to multiply by 3 or 4; the ranges are different for VAP and independent LP(a) testing, meaining your LPa could be as high as 48-64 if converted for non-VAP. I also don't think LPa is related to LDL; it has to do with coagulation and is supposed to be an independent risk factor for CVD but the most potent one. However, there is some thinking that low FT3 and high RT3 caused by Hypo could also elevate Lp(a) unnaturally. Google Lpa and T3.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 14, 2012
at 08:04 PM

By the way, the reason for just enough carbs pre-workout, I believe, is to avoid breaking down muscle to fuel anaerobic exercise, and also to have ketosis kick back in soon thereafter.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 14, 2012
at 03:27 PM

As for carbs before workout, got idea from http://www.free-workout-plans-for-busy-people.com/targeted-ketogenic-diet-plan.html That'd be 2tbsp of honey. Wanted something fast-acting and not digestively burdensome before workout.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 14, 2012
at 03:21 PM

Had been following PHD before starting Keto diet, but hadn't read that article. Very helpful, thanks!

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 14, 2012
at 03:17 PM

Any way to narrow down the Vit D absorption problem? The fact that I've gained 13 lbs (from 70% fat diet) in the last 3 months suggest anything in this regard? Also, before March, I took Vit D with Coconut Milk smoothie; guar gum perhaps play a role in absorption? And, since March, have only been taking 2,000 IU. Have now upped to 10k. Thanks, again!

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 14, 2012
at 03:16 PM

Thanks, Mambo. In Kresser video http://vimeo.com/12515512 he has an LP(a) of 19 and suggests <30mgdl is OK if it's composed of large, buoyant LDL. I suspected Gilbert's from a bit of Googling around; will get this diagnosed eventually. Will stop Calcium supps, already taking Mg (80mg from supps at night; 625mg/160%RDA total) and K2 (comes with my D3) in the morning/afternoon.

5e92edc5a180787a60a252a8232006e9

(345)

on June 14, 2012
at 02:30 PM

34g of carbs from honey? How many tbsp is that? I don't think that's necessary. How about 100g of yams after a workout? But by PSIR, all that means is you're IR to some degree because you normally don't ingest carbs, but you'll become more insulin sensitive once you start eating carbs. Could fail OGTT without prepping. But not a concern if you're eating low carbs.

5e92edc5a180787a60a252a8232006e9

(345)

on June 14, 2012
at 01:59 PM

Your LP(a) is high; it should be under 10. Not sure if fish oil would be good at that level. I also noticed that your Bilirubin is high and it's probably Gilbert's, which is harmless. Have someone look into your retinae after you work out to see yellow residue. You could ask your doc or GI to confirm your high Bilirubin is due to Gilbert's. Other than that, I'd not supplement with Calcium, even in small doses. You seem to have an absorption issue with Vit D; take Mg and Vit K-2.

B8592e62f9804ddabae73c1103d6bcb9

(1956)

on June 13, 2012
at 09:22 PM

Glad I could help. Here's the TSH stuff: http://perfecthealthdiet.com/2010/07/thyroid-more-evidence-that-%E2%80%9Cnormal%E2%80%9D-is-unhealthy/

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 08:04 PM

Thanks, DePaw! Glad to get confirmation on lipids. As for selenium, I've been getting between 125-150% RDA, which I think is roughly 80-110mcg. I shall boost this up a bit via supplementation (avoiding nuts for the time being). On the iodine front, taking it slow at the moment, but as I ramp up I'll incorporate Lugol's Solution. Thanks, again!

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 03:58 PM

By the way, added VAP results.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 03:50 PM

And, finally, I'm having difficulty finding information on how "physiological insulin resistance" might negatively affect my targeted ketogenic diet routine. Could 34g carbs from honey 30-60 minutes pre-workout do more harm than good, or does the workout burn them before they can do much damage? I will be testing BG nonetheless. Thanks, again!

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 03:48 PM

Thanks, Mambo. I'm not sure if this makes a difference, but I started supplementing Calcium Citrate (100-400mg, no more than 200mg at a time) a couple of weeks before my last lab, although have dropped this down to a single, consistent 100mg dose with 80mg of magnesium citrate at night. You think this may be doing more harm than good? Any recommendation on Vit D supplement levels? Do you think I should re-test phosphorus levels ASAP, or six months from now OK?

5e92edc5a180787a60a252a8232006e9

(345)

on June 13, 2012
at 01:40 PM

Your kidney functions are fine: no need for protein restriction. Retest your phosphorus and if you're still high I'd go see an endo/nephrologist to test your PTH given high normal calcium. Also tell them about the Vit D level you're taking.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:53 AM

Mambo, just saw re-read and noticed "if your BUN is too high and GFR too low." So, I think I'm safe!

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:42 AM

Mambo, quick correction: eGFR >59 -> 114

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:41 AM

By the way, Mambo, the GF beef I consume is 78% lean, so it's a little fattier than the usual 85-90%; and, actually, on non-workout days I often cut it down to 6oz, and 8oz on workout days. Also, I've got a detailed food log itemizing all consumption, so 80-100g/d total should be reasonably accurate. And I shall look further into "physiological insulin resistance" and how this affects my honey consumption on workout days. If you got any advice on this, please share. Now I'm worried I may be overloading my system. Next workout day, I will test blood glucose levels after honey.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:27 AM

Thanks, Crowlover. Good point. I added to OP: Thyroxine (T4) 6.4 -> 6.1 T3 Uptake 38 -> 36 Free Thy Index 2.4 -> 2.2

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:27 AM

Thanks, Mambo. I've added the info to the OP: BUN 10 -> 10 Creatinine 0.84 -> 0.87 eGFR >59 -> 114 Calcium 9.6 -> 9.6 So, if Phosphorus isn't a biggie, I guess my kidneys are ok? You mean my Vit D levels last year? 28.6 Wow, protein down to 90% of LBM in kg for me would be about 55g. Seems low, but will definitely seek further reading on this. Please send me anything you got.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:15 AM

No, neuropathy was not formally diagnosed. Basically, it's weakness in my left leg. There was a phase where I'd wake up with pretty significant pain in the leg, but much, much better now. The benign brain thing was formally diagnosed: an arachnoid cyst on the right side of my brain, producing "clonus" in my left leg. this, i assume, caused me to favor my right leg just enough to snowball from there.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on June 13, 2012
at 05:46 AM

Please tell us the exact Thyroid lab values. "in range" is meaningless pretty much since the lab reference ranges are not optimal. Your TSH is higher then it would be, although good improvement.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on June 13, 2012
at 05:44 AM

I too am wondering why more Thyroid testing wasn't done with such a high TSH (now and historically). Maybe that is pending?

5e92edc5a180787a60a252a8232006e9

(345)

on June 13, 2012
at 04:50 AM

What's the benign brain thing causing neuropathy? Is neuropathy formally diagnosed? Someone's gonnan say your fungal toes are a result of candida resulting from leaky gut. I'm not quite sure if they are but you might wanna soak them in apple cider vinegar everyday for 10 minutes and see if they go away.

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2 Answers

1
B8592e62f9804ddabae73c1103d6bcb9

(1956)

on June 13, 2012
at 05:48 PM

Great improvement of the lipids!

Although your total cholesterol has increased and the doctor will regard it 'high, 200-~260mg/dl is actually best for all cause mortality risk (see: http://3.bp.blogspot.com/-pttFtp8eZx0/T3IFYTDzEwI/AAAAAAAAAQ8/Grmm-gHD1yI/s1600/CholesterolMortality.jpg)

Your LDL is also considered 'high' or 'OOR', but looking at your VAP test we see that it pattern A; that is your LDL are nice and fluffy. This LDL is not dangerous, even when the number is a little high, in fact as sex hormones are made from LDL, this is ideal.

Your HDL has increased greatly, due to your increased saturated fat intake. This is great.

Your triglycerides are nice and low, this is good too.


Regards thyroid, you need to ensure adequate selenium as well as iodine. Best sources for selenium are brazil nuts (no more than 2/day), and kidneys. The RDA for both selenium and iodine are a joke, they are the bare minimum to avoid goitre; much better is 200-300ug selenium, and up to 14mg iodine (which the Japanese get). Seaweeds are hard to digest (the Japanese have enzymes others don't), you may find using something like lugol's solution more effective.

You are right thinking 3.6 TSH is a little high, under 1.5 is ideal. But it is much improved from last time and may still be decreasing. Keep an eye on it.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 08:04 PM

Thanks, DePaw! Glad to get confirmation on lipids. As for selenium, I've been getting between 125-150% RDA, which I think is roughly 80-110mcg. I shall boost this up a bit via supplementation (avoiding nuts for the time being). On the iodine front, taking it slow at the moment, but as I ramp up I'll incorporate Lugol's Solution. Thanks, again!

B8592e62f9804ddabae73c1103d6bcb9

(1956)

on June 13, 2012
at 09:22 PM

Glad I could help. Here's the TSH stuff: http://perfecthealthdiet.com/2010/07/thyroid-more-evidence-that-%E2%80%9Cnormal%E2%80%9D-is-unhealthy/

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 14, 2012
at 03:21 PM

Had been following PHD before starting Keto diet, but hadn't read that article. Very helpful, thanks!

1
5e92edc5a180787a60a252a8232006e9

(345)

on June 13, 2012
at 04:35 AM

Your phosphorus is high but not that high. How's your calcium? I don't think it's due to kidney failure but you should check your BUN, creatinine and calculate GFR. I wouldn't be surprised if your BUN is >25 and your creatinine >1 given your heavy meat intake but you shouldn't have any CKD at your age.

Vit D could also be involved, too. But the bioavailability and absorption of Vit D is highly individual. What were your levels before?

Your TC and LDL increase could be due to your thyroid and/or your genetic factor (Apo E4). But in your case, you seem to have low inflammation (CRP) and high HDL that was achieved via exercise, I assume, so I would think your CVD risk is not very high. But you could further assess CVD risk by testing your BP, other inflammation markers, blood stickiness, and LDL particle size.

Your liver enzymes are just a little bit high given your very low CRP but the increase could just be a snapshot, just like your FBG. Your slight FBG increase could be due to physiological insulin resistance, which shouldn't affect your insulin resistance long-term. Get another HbA1C if you think your BG control is failing.

In short, you seem pretty healthy except your thyroid (need T3, T4, RT3 levels and might want to test for HT antibodies). Cut down on protein to your lean body mass level (or about 90% of your LBM in kg) if your BUN is too high and GFR too low. I think your undercounting your total protein intake.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 03:58 PM

By the way, added VAP results.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:41 AM

By the way, Mambo, the GF beef I consume is 78% lean, so it's a little fattier than the usual 85-90%; and, actually, on non-workout days I often cut it down to 6oz, and 8oz on workout days. Also, I've got a detailed food log itemizing all consumption, so 80-100g/d total should be reasonably accurate. And I shall look further into "physiological insulin resistance" and how this affects my honey consumption on workout days. If you got any advice on this, please share. Now I'm worried I may be overloading my system. Next workout day, I will test blood glucose levels after honey.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:53 AM

Mambo, just saw re-read and noticed "if your BUN is too high and GFR too low." So, I think I'm safe!

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:42 AM

Mambo, quick correction: eGFR >59 -> 114

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:27 AM

Thanks, Mambo. I've added the info to the OP: BUN 10 -> 10 Creatinine 0.84 -> 0.87 eGFR >59 -> 114 Calcium 9.6 -> 9.6 So, if Phosphorus isn't a biggie, I guess my kidneys are ok? You mean my Vit D levels last year? 28.6 Wow, protein down to 90% of LBM in kg for me would be about 55g. Seems low, but will definitely seek further reading on this. Please send me anything you got.

5e92edc5a180787a60a252a8232006e9

(345)

on June 13, 2012
at 01:40 PM

Your kidney functions are fine: no need for protein restriction. Retest your phosphorus and if you're still high I'd go see an endo/nephrologist to test your PTH given high normal calcium. Also tell them about the Vit D level you're taking.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on June 13, 2012
at 05:44 AM

I too am wondering why more Thyroid testing wasn't done with such a high TSH (now and historically). Maybe that is pending?

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 06:27 AM

Thanks, Crowlover. Good point. I added to OP: Thyroxine (T4) 6.4 -> 6.1 T3 Uptake 38 -> 36 Free Thy Index 2.4 -> 2.2

5e92edc5a180787a60a252a8232006e9

(345)

on June 14, 2012
at 01:59 PM

Your LP(a) is high; it should be under 10. Not sure if fish oil would be good at that level. I also noticed that your Bilirubin is high and it's probably Gilbert's, which is harmless. Have someone look into your retinae after you work out to see yellow residue. You could ask your doc or GI to confirm your high Bilirubin is due to Gilbert's. Other than that, I'd not supplement with Calcium, even in small doses. You seem to have an absorption issue with Vit D; take Mg and Vit K-2.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 14, 2012
at 03:16 PM

Thanks, Mambo. In Kresser video http://vimeo.com/12515512 he has an LP(a) of 19 and suggests <30mgdl is OK if it's composed of large, buoyant LDL. I suspected Gilbert's from a bit of Googling around; will get this diagnosed eventually. Will stop Calcium supps, already taking Mg (80mg from supps at night; 625mg/160%RDA total) and K2 (comes with my D3) in the morning/afternoon.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 03:48 PM

Thanks, Mambo. I'm not sure if this makes a difference, but I started supplementing Calcium Citrate (100-400mg, no more than 200mg at a time) a couple of weeks before my last lab, although have dropped this down to a single, consistent 100mg dose with 80mg of magnesium citrate at night. You think this may be doing more harm than good? Any recommendation on Vit D supplement levels? Do you think I should re-test phosphorus levels ASAP, or six months from now OK?

4ef079c57d2140bba4dbf4e30240a645

(4413)

on June 13, 2012
at 05:46 AM

Please tell us the exact Thyroid lab values. "in range" is meaningless pretty much since the lab reference ranges are not optimal. Your TSH is higher then it would be, although good improvement.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 13, 2012
at 03:50 PM

And, finally, I'm having difficulty finding information on how "physiological insulin resistance" might negatively affect my targeted ketogenic diet routine. Could 34g carbs from honey 30-60 minutes pre-workout do more harm than good, or does the workout burn them before they can do much damage? I will be testing BG nonetheless. Thanks, again!

5e92edc5a180787a60a252a8232006e9

(345)

on June 14, 2012
at 11:13 PM

That LP(a) range can be very confusing. For VAP tests, I believe you have to multiply by 3 or 4; the ranges are different for VAP and independent LP(a) testing, meaining your LPa could be as high as 48-64 if converted for non-VAP. I also don't think LPa is related to LDL; it has to do with coagulation and is supposed to be an independent risk factor for CVD but the most potent one. However, there is some thinking that low FT3 and high RT3 caused by Hypo could also elevate Lp(a) unnaturally. Google Lpa and T3.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 14, 2012
at 03:27 PM

As for carbs before workout, got idea from http://www.free-workout-plans-for-busy-people.com/targeted-ketogenic-diet-plan.html That'd be 2tbsp of honey. Wanted something fast-acting and not digestively burdensome before workout.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 14, 2012
at 03:17 PM

Any way to narrow down the Vit D absorption problem? The fact that I've gained 13 lbs (from 70% fat diet) in the last 3 months suggest anything in this regard? Also, before March, I took Vit D with Coconut Milk smoothie; guar gum perhaps play a role in absorption? And, since March, have only been taking 2,000 IU. Have now upped to 10k. Thanks, again!

5e92edc5a180787a60a252a8232006e9

(345)

on June 14, 2012
at 02:30 PM

34g of carbs from honey? How many tbsp is that? I don't think that's necessary. How about 100g of yams after a workout? But by PSIR, all that means is you're IR to some degree because you normally don't ingest carbs, but you'll become more insulin sensitive once you start eating carbs. Could fail OGTT without prepping. But not a concern if you're eating low carbs.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 14, 2012
at 08:04 PM

By the way, the reason for just enough carbs pre-workout, I believe, is to avoid breaking down muscle to fuel anaerobic exercise, and also to have ketosis kick back in soon thereafter.

5e92edc5a180787a60a252a8232006e9

(345)

on June 14, 2012
at 11:15 PM

I'd definitely get the straight dope on your HT, check FT3 and RT3. Ur already on selenium so start Iodine very slowly in small increments like PHD says and then see whether your LDL and Lpa fall. I have a feeling it might.

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 15, 2012
at 04:21 AM

Thanks, Mambo. I'll look further into the things you mentioned, and do a more thorough thyroid panel next time around. Getting ~100mcg selenium and 100% iodine currently, but will add a supplemental ~125mcg of selenium starting tomorrow, and double iodine once per month.

5e92edc5a180787a60a252a8232006e9

(345)

on June 19, 2012
at 02:27 PM

Here's an article, a bit dated, showing that short-term hypothyroidism which lowers T3 can increase both LDL AND LP(a). The T3 angle looks promising.

5e92edc5a180787a60a252a8232006e9

(345)

on June 20, 2012
at 02:40 AM

http://www.ncbi.nlm.nih.gov/pubmed/7760967

A66cef2c4440ce1d7113dfcf33ae5f52

(10)

on June 24, 2012
at 03:08 PM

Interesting; thanks, Mambo.

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