4

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Anyone tried 5-HTP for sleep?

Answered on August 19, 2014
Created November 12, 2011 at 1:07 AM

And is so, how did it work or not work for you?

Thanks

Jeff

A141571ee2453db572c9d3222657bf6b

(756)

on November 18, 2011
at 02:53 AM

daz, agreed, however I did not mention this route because it is commonly argued that excessive melatonin supplementation can be problematic, approaching dependence, and this is an easy trap to fall into. if melatonin is used directly it should be limited to three weeks or so just like any other artificial intervention to allow oneself to address the underlying issue.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on November 12, 2011
at 04:55 AM

or could bypass tryptophan, 5-htp & serotonin & go straight for melatonin (in sub milligram amount). But none of these will work imo, unless you are actually deficient in melatonin; confirm by doing a midnight melatonin saliva test. In fact if you are already producing adequate night-time melatonin, any of these supps may worsen your sleep (updated comment to fix typo).

543a65b3004bf5a51974fbdd60d666bb

(4493)

on November 12, 2011
at 02:20 AM

or could bypass tryptophan, 5-htp & serotonin & go straight for melatonin (in sub gram amount). But none of these will work imo, unless you are actually deficient in melatonin; confirm by doing a midnight melatonin saliva test. In fact if you are already producing adequate night-time melatonin, any of these supps may worsen your sleep

543a65b3004bf5a51974fbdd60d666bb

(4493)

on November 12, 2011
at 02:12 AM

or could bypass 5-htp & serotonin & go straight for melatonin (in sub gram amount). But none of these will work imo, unless you are actually deficient in melatonin; confirm by doing a midnight melatonin saliva test. In fact if you are already producing adequate night-time melatonin, any of these supps may worsen your sleep.

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6 Answers

1
A141571ee2453db572c9d3222657bf6b

(756)

on November 12, 2011
at 01:28 AM

this hits on the individual chemistry angle where people are often different. have you tried taking 5-htp already? if you have, did you notice any cognitive effect? did you notice any digestive effect?

5-htp makes me manic and I can discern no benefit for sleep. while in some people the pathway can be slow or broken, 5-htp bypasses the hydroxylation mechanism resulting in a relatively unregulated bump of serotonin. even if a generous amount gets converted to melatonin, you still might have too much serotonin floating around to effectively fall asleep.

as a stop-gap for correcting your sleep issue, I encourage taking l-tryptophan instead. 5-htp is converted from l-tryptophan, so your body will use what it needs. 500-1000mg about an hour before bedtime should suffice.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on November 12, 2011
at 02:12 AM

or could bypass 5-htp & serotonin & go straight for melatonin (in sub gram amount). But none of these will work imo, unless you are actually deficient in melatonin; confirm by doing a midnight melatonin saliva test. In fact if you are already producing adequate night-time melatonin, any of these supps may worsen your sleep.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on November 12, 2011
at 02:20 AM

or could bypass tryptophan, 5-htp & serotonin & go straight for melatonin (in sub gram amount). But none of these will work imo, unless you are actually deficient in melatonin; confirm by doing a midnight melatonin saliva test. In fact if you are already producing adequate night-time melatonin, any of these supps may worsen your sleep

543a65b3004bf5a51974fbdd60d666bb

(4493)

on November 12, 2011
at 04:55 AM

or could bypass tryptophan, 5-htp & serotonin & go straight for melatonin (in sub milligram amount). But none of these will work imo, unless you are actually deficient in melatonin; confirm by doing a midnight melatonin saliva test. In fact if you are already producing adequate night-time melatonin, any of these supps may worsen your sleep (updated comment to fix typo).

A141571ee2453db572c9d3222657bf6b

(756)

on November 18, 2011
at 02:53 AM

daz, agreed, however I did not mention this route because it is commonly argued that excessive melatonin supplementation can be problematic, approaching dependence, and this is an easy trap to fall into. if melatonin is used directly it should be limited to three weeks or so just like any other artificial intervention to allow oneself to address the underlying issue.

0
D061ae1ab11248b415e3e8062cd79038

on November 12, 2011
at 10:49 AM

I tried 5-HTP for better sleep. I started with 50mg and went up to 400mg taken right before bed. Unfortunately, it didn't help me fall asleep quicker, which was my main problem. I did notice a considerable effect on sleep quality, though. My sleep was a lot deeper, my dreams were extremely vivid and I was feeling refreshed in the morning even though I didn't sleep for more than 7 hours.

0
Medium avatar

on November 12, 2011
at 07:39 AM

Yes, I tried it. But can't say much about results, for the following reasons.

I wasn't having sleep problems. Was more interested to sleep more deeply. Was doing well, wanted to do better.

So I explored melatonin, theanine, GABA, and 5-HTP. In various doses, and various combinations. No way to know which had any particular effect.

I kept sleeping well. As I do today.

Main thing I would say: make sure your sleeping room is dark. Regardless, wear eye shades. Minimize caffeine late in day. Don't be stupid with alcohol, day or night. Get exercise. Consider practicing meditation of some form, or various methods of relaxation that may not be "sleep" per se but are very much appreciated by CNS (central nervous system).

And when you find yourself awake late at night, don't add worry to the mix. Reclining quietly is way, way more restful than reclining with agitation.

If intense emotional and/or mental issues keep you awake, that's different. Get a good therapist, and get to work.

0
Fe87afa634afe26f4f6fd956abe0b46a

(565)

on November 12, 2011
at 03:05 AM

I have found that it has a calming effect for me. I've used it for sleep purposes and also a few times for high anxiety days at work. It didn't make me doze off during the day, but it did lessen anxiety. As such it definitely helps me fall asleep easier as well. It does not necessarily keep me asleep though.

0
8496289baf18c2d3e210740614dc9082

on November 12, 2011
at 01:33 AM

The action of 5-HTP in promoting sleep is to increase CNS serotonin production. As such, it is typically not effective except in situations of chronic insomnia. That being said, I haven't personally tried it.

0
Df7cf48be85c91165f9f39f1fe462e41

on November 12, 2011
at 01:16 AM

I have tried 5-Htp for sleep, and for me, melatonin seems to work better. I have had friends be the exact opposite and had the 5-Htp work better. I think it's just one of those things that you'll have to try to see how you like it.

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