For MTHFR, are the B12, folate found in liver or egg yolks already methylated? And does cooking damage them? Or are supplements needed? I started on methylfolate in the AM and methyl B12 at night, and have noticed some improvements in sleep... (more)
I'v spent an enormous amount of time and read all kinds of theoretical info about methylation causing excess sulfur and ammonia. Does anyone here have that issue or is this all ivory tower theoretical stuff? Ever since going paleo and... (more)
This may be a bit of a long post. Apologies in advance: I wanted to just get it out there. I began taking B12 (methylcobalamin) and folate (methylfolate), & ~2,500 IU D3/ 500mg K2 recently. While the symptoms & dramatic... (more)
Pasted below is the lab result for some genetic testing I had done. What the heck does this mean (in plain english please), and Could it have any potential relevance to someone who seems to be having issues with amines/salicylates? Here's the... (more)
I am homozygous recessive for MTRR a66g, which is methionine synthase reductase. According to 23 and me i have lots of methylation problems, but none with the MTHFR gene. Does anybody have a good understanding of this and what I should do given... (more)
Hi Guys, I'm about 2 months into a strict primal diet that does include raw dairy and nuts, but does not include starchy veggies. I look and feel better already and I'm really excited to watch my progression in the upcoming year. One thing I've... (more)
After 10-15 years of on and off smoking, I'm done done done. We're getting ready to start a family, and with the switch to paleo, I'm focusing on healing my body after all the damage I've done. Are there any supplements or foods I should focus... (more)
I recently found out (from 23andme) that I am heterogeneous (one copy of the "bad" gene) for the MTHFR C677T polymorphism. This means that my body has reduced ability to convert folate into the active form of folate (5-methyltetrahydrafolate).... (more)
While trying to further optimize my diet, I recently noticed that I have a homozygous C677T (TT genotype) MTHFR enzyme. Homozygous rs1801133(T;T) individuals have ~30% of the expected MTHFR enzyme activity, and rs1801133(C;T) heterozygotes... (more)
Do you agree with paleo-censorship?
Fun article about fermented foods in the Arctic circle
Who wants to do Whole30 with me?