4

votes

Alzheimer and Ketosis

Answered on September 12, 2014
Created December 15, 2010 at 8:32 PM

My grandad was just diagnosed with alzheimer. My mom is now on a frantic search to learn as much about the disease as possible. I've heard a good about of noise about ketosis helping alzheimer's but haven't found too much of substance. Does a ketogenic diet help relieve alzheimer's symptoms?

D31a2a2d43191b15ca4a1c7ec7d03038

(4134)

on January 14, 2011
at 12:08 PM

Thank you for posting the links to Dr. Newport's blog. Her posts are most useful.

82166cc32b6cf26de33b69f58fb583b1

on December 16, 2010
at 06:47 PM

Yes, Dr. Newport's websites are the place to go on this subject. She put her husband on a ketogenic diet (using MCT oil and coconut oil) and his dementia improved a great deal.

47a42b6be94caf700fce9509e38bb6a4

(9647)

on December 16, 2010
at 12:32 AM

Yes, that looks really good. The first link in the dementia section -- http://evolutionarypsychiatry.blogspot.com/2010/09/alzheimers-and-hyperglycemia.html -- will direct you back to the chapter in Taubes that talks about Alzheimer's, probably another good place to start; will get you some studies to look at also.

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7 Answers

5
3020fb359dfbedaf90f1611b036d3432

(1138)

on December 15, 2010
at 09:49 PM

I've recently become addicted (pun intended) to reading the Evolutionary Psychiatry blog by Dr. Emily Deans. The link provided breaks down her post archive by condition, so just scroll down to the 'Dementia' section and you can find all the posts on Alzheimer's.

47a42b6be94caf700fce9509e38bb6a4

(9647)

on December 16, 2010
at 12:32 AM

Yes, that looks really good. The first link in the dementia section -- http://evolutionarypsychiatry.blogspot.com/2010/09/alzheimers-and-hyperglycemia.html -- will direct you back to the chapter in Taubes that talks about Alzheimer's, probably another good place to start; will get you some studies to look at also.

3
0d2dec01a5ed9363a9915e111ae13f7e

on December 15, 2010
at 08:46 PM

Dig into this blog, Dr Newport has some good info on ketosis and Alzheimer's:

http://coconutketones.blogspot.com/

http://coconutketones.blogspot.com/2009_05_01_archive.html to get you hooked on the idea.

82166cc32b6cf26de33b69f58fb583b1

on December 16, 2010
at 06:47 PM

Yes, Dr. Newport's websites are the place to go on this subject. She put her husband on a ketogenic diet (using MCT oil and coconut oil) and his dementia improved a great deal.

D31a2a2d43191b15ca4a1c7ec7d03038

(4134)

on January 14, 2011
at 12:08 PM

Thank you for posting the links to Dr. Newport's blog. Her posts are most useful.

2
D31a2a2d43191b15ca4a1c7ec7d03038

on January 17, 2011
at 11:16 AM

Yes, this study might be of interest.

http://www.nutritionandmetabolism.com/content/2/1/28

Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that primarily strikes the elderly. Studies in both humans and animal models have linked the consumption of cholesterol and saturated fats with amyloid-?? (A??) deposition and development of AD. Yet, these studies did not examine high fat diets in combination with reduced carbohydrate intake. Here we tested the effect of a high saturated fat/low carbohydrate diet on a transgenic mouse model of AD.

Conclusion: Previous studies have suggested that diets rich in cholesterol and saturated fats increased the deposition of A?? and the risk of developing AD. Here we demonstrate that a diet rich in saturated fats and low in carbohydrates can actually reduce levels of A??. Therefore, dietary strategies aimed at reducing A?? levels should take into account interactions of dietary components and the metabolic outcomes, in particular, levels of carbohydrates, total calories, and presence of ketone bodies should be considered.


This article at the "Pediatric Journal" is an overview of current uses for ketogenic diets. It contains reference links to many studies, including the one above.

http://pediatrics.aappublications.org/cgi/content/full/119/3/535


I, too, recommend reading Dr. Mary Newport's blog:

http://coconutketones.blogspot.com/

All the best to you.

1
B1525054ecd4ce6c616a8a829b725f75

on December 16, 2010
at 06:14 PM

A person with alzheimers is experiencing insulin resistance in the brain. This starves the brain of fuel and so you need to get a different fuel to the brain. A ketogenic diet will do this.

1
4781cf8ae1bfcb558dfb056af17bea94

(4359)

on December 16, 2010
at 02:03 AM

  1. There was a lot of buzz about coconut oil and MCTs on the theory that brain cells in the AD brain lose the ability to uptake glucose (so-called 3rd form of diabetes), so having some ketones floating around allows them to eat... A full ketosis diet is hard to do and may not be warranted (the beauty of MCTs). I haven't heard any updates in the past year or two though... Hopefully, that's not a sign that the method isn't sound.

  2. Similar story for methylene blue (blue acquarium die)... A UK company was trying to lauch a drug called Rember that was basicaly just methylene blue. There was a lot of buzz a while back and then nothing... You can buy mehtylene blue in a pet store and, if you are smart and careful, figure out how to titrate it to the proper dose... I don't know anything about side effects or safety issues so you should definitely do your research before trying something like this.

  3. I've also heard good things about high dose B vitamins... Claims that it can stop progression in its tracks.

The basic anti-inflammatories like vit D, fish oil (or better yet, actual fish; like wild salmon), turmeric, etc may also help slow progression a bit.

Go to the imminst forums for more and much better info that you will find here.

1
083db595dab64306570b02c6e021bbf0

on December 15, 2010
at 09:30 PM

Also, check out Phosphatidlyserine.

1
Ce57a94251224f9696faf47f9ca630a0

(858)

on December 15, 2010
at 09:03 PM

I heard daily doses of coconut oil (extra virgin, of course) helps. I have no links to back that up, but I bet there are some out there.

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