7

votes

Protein and IGF1

Commented on November 22, 2014
Created August 19, 2012 at 8:26 PM

I'm watching the documentary someone else posted on here about fasting and it says that eating fair amounts of protein is like driving your car with your foot on the peddle; it causes your body to go into 'go go' mode which makes you more susceptible to some cancers and diabetes because 'you're cells are growing too fast for damage to be efficiently repaired'

The show says that you should fast but also restrict your intake of protein replacing it with 'more plant based food.' I thought protein was the good guy?? Their not talking about loads of protein either, they're saying you shouldn't eat much of it but what about body composition etc? Does anyone fast for this reason or restrict their protein?

http://www.youtube.com/watch?v=Pfna7nV7WaM

141171c0810650168d82601d85cfa5a3

(415)

on May 15, 2013
at 08:10 PM

"If the body produces its own IGF1 does that still increase cancer risks." All the studies of low carb diets on animals and humans show it slows, stops or reverses cancer growth. Possibly by lowering serum IGF-1 but lets not forget insulin too. Insulin is also a growth factor which is lowered best by carbohydrate restriction.

Medium avatar

(115)

on April 06, 2013
at 06:24 PM

a lot of research is just BS and made on the wrong persons and in the wrong intervals.

6b365c14c646462210f3ef6b6fecace1

(1784)

on August 21, 2012
at 02:41 PM

i agree that it does have great benefits, but one of the main concerns is it's non selective for normal and damaged cells in the body. promoting the growth of damaged cells is not desired, and if a person has consistently elevated levels of IGF-1, this is a "recipe for disaster" ( sorry for the corny idiom - it's early here)

Bb3d1772b28c02da2426e40dfcb533f5

(5391)

on August 20, 2012
at 02:49 AM

^ I think this is part of why rosedales diet is very low carb, medium protein, high fat, at least from his more recent blog post I got this impression.

7a6529ea25b655132fe58d793f95547a

(2030)

on August 19, 2012
at 09:12 PM

Cool, thanks for the link RawNut

1edb06ded9ccf098a4517ca4a7a34ebc

(14932)

on August 19, 2012
at 08:58 PM

+1 for linking ergo-log.com. My favorite fitness/health website.

1edb06ded9ccf098a4517ca4a7a34ebc

(14932)

on August 19, 2012
at 08:34 PM

I have read conflicting reports on protein and IGF-1 elevation. Plus, IGF-1 is not really the demon it is made out to be either. Seems like a red herring to me. Plus, I'd rather die at 50 while being athletic and productive than live to 100 with alzheimer's and a limp dick. But that's just me.

1edb06ded9ccf098a4517ca4a7a34ebc

(14932)

on August 19, 2012
at 08:32 PM

I have read conflicting reports on protein and IGF-1 elevation. Plus, IGF-1 is not really the demon it is made out to be either. I do not know whey protein would cause EXCESSIVE IGF-1 only in humans, but not in other animals either. Seems like a red herring to me. Plus, I'd rather die at 50 while being athletic and productive than live to 100 with alzheimer's and a limp dick. But that's just me.

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6 Answers

5
141171c0810650168d82601d85cfa5a3

(415)

on August 19, 2012
at 08:53 PM

It depends on the context of the diet. If you're eating low protein, adding protein will increase serum IGF-1 levels. If you're low carb, adding carbs will raise it. The The nice thing about low carb is your serum IGF-1 will be low but your muscle cells will start to produce their own IGF-1.

This article explains the study in more detail. http://www.ergo-log.com/lowcarbwithouttraining.html

1edb06ded9ccf098a4517ca4a7a34ebc

(14932)

on August 19, 2012
at 08:58 PM

+1 for linking ergo-log.com. My favorite fitness/health website.

Bb3d1772b28c02da2426e40dfcb533f5

(5391)

on August 20, 2012
at 02:49 AM

^ I think this is part of why rosedales diet is very low carb, medium protein, high fat, at least from his more recent blog post I got this impression.

7a6529ea25b655132fe58d793f95547a

(2030)

on August 19, 2012
at 09:12 PM

Cool, thanks for the link RawNut

1
77877f762c40637911396daa19b53094

(78447)

on August 21, 2012
at 02:12 PM

You've raised an important point that is very relevant to paleo - feeding frequency.

Intermittent fasting is consistent with what would occur in ancestral dietary practices.

Modern diet IGF-1 levels are abnormally high.

Protein should not be a concern provided you practice intermittent fasting as per the BBC Horizon program you watched.

1
1edb06ded9ccf098a4517ca4a7a34ebc

on August 19, 2012
at 08:37 PM

I have read conflicting reports on protein and IGF-1 elevation. Plus, IGF-1 is not really the demon it is made out to be either. In fact, if you google "IGF-1 health benefits performance," you'll find a lot of interesting links.

"According to researchers, IGF-1 increases lean body mass, reduces fat, builds bone, muscle, and nerves. By taking it directly you bypass the pituitary gland which may be burnt out by the aging process."

When they say "by taking it" they're referring to a deer antler, which contains large amounts of it. From what I recall, deer antler is a historical delicacy.

Sounds good to me.

6b365c14c646462210f3ef6b6fecace1

(1784)

on August 21, 2012
at 02:41 PM

i agree that it does have great benefits, but one of the main concerns is it's non selective for normal and damaged cells in the body. promoting the growth of damaged cells is not desired, and if a person has consistently elevated levels of IGF-1, this is a "recipe for disaster" ( sorry for the corny idiom - it's early here)

Medium avatar

(115)

on April 06, 2013
at 06:24 PM

a lot of research is just BS and made on the wrong persons and in the wrong intervals.

0
393a548661f15649ab59f332e70c4d46

on September 03, 2013
at 02:05 PM

Marcus can you post the link for info regarding carbs and IGF-1 promotion. It's exactly what I am searching for.

99a65959b498d9a5335c3ef710e2214f

on November 22, 2014
at 01:51 PM

The studies I've seen show that carbs don't raise IGF-1.

0
1d08c3f2ce3bd72528ccf957d422d976

on April 24, 2013
at 11:21 AM

HI there, I'm in Australia and just saw the documentary 'Eat, Fast and Live Longer' as was struck too by the comment by the researcher about the association between IGF1 and cancer and that protein stimulates IGF1 levels. I'd never even seen IGF1 mentioned much in my readings about Paleo or low-carb. I partially understand your explanation Rawnut but am still wondering if a higher protein diet will raise the IGF1 levels and a low carb diet will not reduce the level. If the body produces its own IGF1 does that still increase cancer risks. It would be great to see some discussion of this issue in the many low carb or Paleo blogs. Has anyone seen any more discussion since the original question was posted above. Thanks all.

141171c0810650168d82601d85cfa5a3

(415)

on May 15, 2013
at 08:10 PM

"If the body produces its own IGF1 does that still increase cancer risks." All the studies of low carb diets on animals and humans show it slows, stops or reverses cancer growth. Possibly by lowering serum IGF-1 but lets not forget insulin too. Insulin is also a growth factor which is lowered best by carbohydrate restriction.

0
082418f5a6a97580ba2f4780f911fe62

on December 23, 2012
at 12:10 PM

They ignore that fact that carbohydratges promote IGF-1 the most...replacing protein with more carbs makes no sesnse. THe best way to lower IGF is actually lowering both protein and carbs and increasing fat consumption.

99a65959b498d9a5335c3ef710e2214f

on November 22, 2014
at 01:53 PM

Which study?

 

the studies I've seen show that carbs don't raise IGF-1

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