5

votes

Antioxidants (Vitamin C) stop exercise induced increased insulin sensitivity

Answered on September 12, 2014
Created September 11, 2012 at 9:41 AM

http://www.ncbi.nlm.nih.gov/m/pubmed/19433800/

As we know, exercise increases insulin sensitivity. This study says vitamin C and antioxidants negate that effect.

Apparently it shuts down the benefits of autophagy too. http://metamodern.com/2010/09/26/antioxidants-block-cell-repair/

So does this mean we should not take Vit C?

Or should we time intake appropriately? The study doesn't mention timing. I wonder if taking Vit C at night, long after exercise, and not during the autophagy phase of a fast, would help?

Cf08ad26759fdd206a2c9f9385080a57

(995)

on April 03, 2014
at 05:50 AM

You generally want a diet high in antioxidants if you exercise regularly. You'll still get the same benefits (possibly with greater performance metrics) with less damage to your body, so you can get up and do it again the next day.

8b9c2dcd3dfc929a0428d3d6dac4918e

(70)

on April 03, 2014
at 04:11 AM

Makes sense. Its stressed based, same as the adaptions in the liver. Just don't take artificially high dose supplements right before exercise. Is there not any vit c in your food?

510bdda8988ed0d4b0ec0b738b4edb73

(20898)

on November 07, 2012
at 04:12 PM

I would inagine there no/little effect. The hormetic stress of exercise is the oxidative damage that results from all of the free radicals created during combustion. That's what the antioxidants undo.

Medium avatar

(2417)

on November 07, 2012
at 06:00 AM

Without INSULIN (not insult, lol)

Medium avatar

(2417)

on November 07, 2012
at 05:59 AM

Do antioxidants stop the non-insulin mediated glucose uptake process which is stimulated by training? (GLUT is mobilized to the surface of muscle cells to take sugar in without insulin to stimulate the process) ??

6120c989fd5b69f42a0834b69b87955b

(24553)

on September 25, 2012
at 09:42 PM

Hey, so my German host father wasn't just being a controlling weirdo when he chastised me for eating my St. Nicolas Day mandarin orange as a late night snack, and suggested I save it for morning.

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3 Answers

1
510bdda8988ed0d4b0ec0b738b4edb73

(20898)

on November 06, 2012
at 11:33 PM

Yeah, this is pretty well known in the exercise community. Antioxidents blunt the hormetic stressor that exercise provides so you actually don't get the benefits from the exercise. Even ibuprofin PWO will limit the benefit you get from the workout.

Medium avatar

(2417)

on November 07, 2012
at 06:00 AM

Without INSULIN (not insult, lol)

Medium avatar

(2417)

on November 07, 2012
at 05:59 AM

Do antioxidants stop the non-insulin mediated glucose uptake process which is stimulated by training? (GLUT is mobilized to the surface of muscle cells to take sugar in without insulin to stimulate the process) ??

510bdda8988ed0d4b0ec0b738b4edb73

(20898)

on November 07, 2012
at 04:12 PM

I would inagine there no/little effect. The hormetic stress of exercise is the oxidative damage that results from all of the free radicals created during combustion. That's what the antioxidants undo.

Cf08ad26759fdd206a2c9f9385080a57

(995)

on April 03, 2014
at 05:50 AM

You generally want a diet high in antioxidants if you exercise regularly. You'll still get the same benefits (possibly with greater performance metrics) with less damage to your body, so you can get up and do it again the next day.

1
3846a3b61bc9051e4baebdef62e58c52

(18635)

on September 11, 2012
at 07:53 PM

Very interesting. I think this "I???m sure that there are further insights (and corrections) that can be extracted from the literature in place today, and I look forward to seeing that literature itself become half-obsolete next year." says it all though. For the time being I will stick to vitamin D and magnesium as my only supplements.

The problem with vitamin C at night is that ....well that is exactly when you are fasting. If you wanted to time it, it would seem taking it with your meals only is your best bet.

6120c989fd5b69f42a0834b69b87955b

(24553)

on September 25, 2012
at 09:42 PM

Hey, so my German host father wasn't just being a controlling weirdo when he chastised me for eating my St. Nicolas Day mandarin orange as a late night snack, and suggested I save it for morning.

0
Cf08ad26759fdd206a2c9f9385080a57

(995)

on April 03, 2014
at 05:58 AM

http://www.ncbi.nlm.nih.gov/pubmed/21325105

"Our results indicate that administration of antioxidants during strenuous endurance training has no effect on the training-induced increase in insulin sensitivity in healthy individuals."

The half life for supplemental vitamin c may be a short as 30 minutes.

I like the idea of taking it at night or after exercise to reduce cortisol, but anytime is a good time for vitamin c (unless you have the genetic mutations to store a ton of iron.)

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