As we know, exercise increases insulin sensitivity. This study says vitamin C and antioxidants negate that effect.
Apparently it shuts down the benefits of autophagy too. http://metamodern.com/2010/09/26/antioxidants-block-cell-repair/
So does this mean we should not take Vit C?
Or should we time intake appropriately? The study doesn't mention timing. I wonder if taking Vit C at night, long after exercise, and not during the autophagy phase of a fast, would help?
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Yeah, this is pretty well known in the exercise community. Antioxidents blunt the hormetic stressor that exercise provides so you actually don't get the benefits from the exercise. Even ibuprofin PWO will limit the benefit you get from the workout.
Very interesting. I think this "I???m sure that there are further insights (and corrections) that can be extracted from the literature in place today, and I look forward to seeing that literature itself become half-obsolete next year." says it all though. For the time being I will stick to vitamin D and magnesium as my only supplements.
The problem with vitamin C at night is that ....well that is exactly when you are fasting. If you wanted to time it, it would seem taking it with your meals only is your best bet.
"Our results indicate that administration of antioxidants during strenuous endurance training has no effect on the training-induced increase in insulin sensitivity in healthy individuals."
The half life for supplemental vitamin c may be a short as 30 minutes.
I like the idea of taking it at night or after exercise to reduce cortisol, but anytime is a good time for vitamin c (unless you have the genetic mutations to store a ton of iron.)